Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Mark A, Greenough"'
Autor:
Mark A. Greenough, Darius J. R. Lane, Rachelle Balez, Helena Targa Dias Anastacio, Zhiwen Zeng, Katherine Ganio, Christopher A. McDevitt, Karla Acevedo, Abdel Ali Belaidi, Jari Koistinaho, Lezanne Ooi, Scott Ayton, Ashley I. Bush
Publikováno v:
Cell death and differentiation. 29(11)
Mutations in presenilin 1 and 2 (PS1 and PS2) cause autosomal dominant familial Alzheimer’s disease (FAD). Ferroptosis has been implicated as a mechanism of neurodegeneration in AD since neocortical iron burden predicts Alzheimer’s disease (AD) p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcbc3780876ccc741a9443de1092f9ae
https://pubmed.ncbi.nlm.nih.gov/35449212
https://pubmed.ncbi.nlm.nih.gov/35449212
Publikováno v:
Frontiers in Aging Neuroscience, Vol 6 (2014)
Copper is critical for the Central Nervous System (CNS) development and function. In particular, different studies have shown the effect of copper at brain synapses, where it inhibits Long Term Potentation (LTP) and receptor pharmacology. Paradoxical
Externí odkaz:
https://doaj.org/article/081ab00dc047408c92e1e3f2a00ee5d8
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e62811 (2013)
Dietary copper is essential for multicellular organisms. Copper is redox active and required as a cofactor for enzymes such as the antioxidant Superoxide Dismutase 1 (SOD1). Copper dyshomeostasis has been implicated in Alzheimer's disease. Mutations
Externí odkaz:
https://doaj.org/article/2d121f1c346242a79eeae9728a0b5428
Autor:
Alessandro Alimonti, Michael Aschner, Terry Jo V. Bichell, Stephen C. Bondy, Valentina Borghesani, Aaron B. Bowman, Sonia Brescianini, David R. Brown, Maria C. Buscarinu, Ashley I. Bush, Bárbara R. Cardoso, Benedetta Cerasoli, Jingyuan Chen, James R. Connor, Lucio G. Costa, Peter J. Crouch, Melisa del Barrio, David C. Dorman, Peter Faller, Michela Ferraldeschi, Arianna Fornasiero, Andreas M. Grabrucker, Stefanie Grabrucker, Mark A. Greenough, Timothy C. Halbesma, Dominic J. Hare, Christelle Hureau, Hong Jiang, Katja M. Kanninen, Henna Konttinen, Katarína Lejavová, Frank W. Lewis, Wenjing Luo, Tarja Malm, Dinamene Marques dos Santos, Ana P. Marreilha dos Santos, Carlo Mattei, Rosella Mechelli, Alexandra I. Mot, Anne M. Nixon, Carlos M. Opazo, George Perry, Anna Pino, Germán Plascencia-Villa, Alejandra Ramírez Muñoz, Giovanni Ristori, Silvia Romano, Per M. Roos, Carlo Salustri, Marco Salvetti, Mariacristina Siotto, Rosanna Squitti, Maria A. Stazi, Peng Su, David Tétard, K. Grace Tipps, Mariacarla Ventriglia, Anthony R. White, Miguel José-Yacamán
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::04a3bc5cee762b5d7442ae6192a9cf00
https://doi.org/10.1016/b978-0-12-804562-6.00025-7
https://doi.org/10.1016/b978-0-12-804562-6.00025-7
Autor:
Peter J, Crouch, Maria S, Savva, Lin W, Hung, Paul S, Donnelly, Alexandra I, Mot, Sarah J, Parker, Mark A, Greenough, Irene, Volitakis, Paul A, Adlard, Robert A, Cherny, Colin L, Masters, Ashley I, Bush, Kevin J, Barnham, Anthony R, White
Publikováno v:
Journal of neurochemistry. 119(1)
Impaired metal ion homeostasis causes synaptic dysfunction and treatments for Alzheimer's disease (AD) that target metal ions have therefore been developed. The leading compound in this class of therapeutic, PBT2, improved cognition in a clinical tri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d82cd39582042676c6770b29f449e479
https://pubmed.ncbi.nlm.nih.gov/21797865
https://pubmed.ncbi.nlm.nih.gov/21797865
Autor:
Mark K. Greenough
Publikováno v:
Civil War History. 31:5-23
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4d2786388f79b6ea46da0bdd9f152853
https://doi.org/10.1353/cwh.1985.0000
https://doi.org/10.1353/cwh.1985.0000