Výsledky vyhledávání - "Mark A, Dayton"

Free insulin‐like growth factor‐I and breast cancer risk

Autor: Mylinh Smith, M. Javad Khosravi, Herbert Yu, Anastasia Diamandi, Benjamin D.L. Li, Mark A. Dayton, Hans J. Berkel

Publikováno v: International Journal of Cancer. 91:736-739

Insulin-like growth factor-I (IGF-I) has mitogenic and anti-apoptotic effects on breast cancer cells. Epidemiologic studies have shown that high plasma levels of IGF-I and low levels of IGF binding protein (BP)-3 are associated with increased risk of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f9db00c2c04381b8c358fb40c8c361db
https://doi.org/10.1002/1097-0215(200002)9999:9999<::aid-ijc1111>3.0.co

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Acute Mixed Lineage Leukemia With an inv(8)(p11q13) Resulting in Fusion of the Genes for MOZ and TIF2

Autor: Jian Liang, Leonard Prouty, B. Jill Williams, Mark A. Dayton, Kerry L. Blanchard

Publikováno v: Blood. 92:2118-2122

Chromosomal abnormalities in acute leukemia have led to the discovery of many genes involved in normal hematopoiesis and in malignant transformation. We have identified the fusion partners in an inv(8)(p11q13) from a patient with acute mixed lineage

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3a5c5679973f974b9c90951ce13b5ffc
https://doi.org/10.1182/blood.v92.6.2118.418k09_2118_2122

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Human B cell lines express the interferon gamma gene

Autor: Thomas J. Knobloch, David Benjamin, Mark A. Dayton

Publikováno v: Cytokine. 4:454-460

Interferon gamma (IFN-gamma) production has been attributed exclusively to activated T cells and NK cells. We sought to determine whether human B cells express IFN-gamma. We studied 28 B cell lines including Epstein-Barr virus (EBV)+ normal lymphobla

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c3361efa2b2612a5401189a5c5f580c
https://doi.org/10.1016/1043-4666(92)90005-c

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Human B-cell interleukin-10: B-cell lines derived from patients with acquired immunodeficiency syndrome and Burkitt's lymphoma constitutively secrete large quantities of interleukin-10 [see comments]

Autor: Mark A. Dayton, Thomas J. Knobloch, David Benjamin

Publikováno v: Blood. 80:1289-1298

A recent addition to the lymphokine network is human IL-10 (hIL-10). This novel lymphokine has striking homology to BCRF1 protein, the product of a previously uncharacterized open-reading frame in the Epstein-Barr virus (EBV) genome. To date, IL-10 e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ff0e8d231c24db4da18cf62b853c915e
https://doi.org/10.1182/blood.v80.5.1289.1289

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Phase I studies of interleukin (IL)-2 and rituximab in B-cell non-hodgkin's lymphoma: IL-2 mediated natural killer cell expansion correlations with clinical response

Autor: William Larry, Gluck, Deborah, Hurst, Alan, Yuen, Alexandra M, Levine, Mark A, Dayton, Jon P, Gockerman, Jennifer, Lucas, Kimberly, Denis-Mize, Barbara, Tong, Dawn, Navis, Anita, Difrancesco, Sandra, Milan, Susan E, Wilson, Maurice, Wolin

Publikováno v: Clinical cancer research : an official journal of the American Association for Cancer Research. 10(7)

Expansion and activation of natural killer (NK) cells with interleukin-2 (IL-2) may enhance antibody-dependent cellular cytotoxicity (ADCC), an important mechanism of rituximab activity. Two parallel Phase I studies evaluated combination therapy with

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7a26f8b39e42234dcba5d7ecdad20f9f
https://pubmed.ncbi.nlm.nih.gov/15073100

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Modulation of CD4 cell cytokine production by colon cancer-associated mucin

Autor: Pierre L. Triozzi, Julian A. Kim, Mark A. Dayton, Wayne Aldrich

Publikováno v: Cancer immunology, immunotherapy : CII. 48(9)

Mucins have been implicated in tumor-associated immunosuppression. The possibility that colon cancer mucin (CCM) may modulate T-helper 1 (TH1) activity was evaluated by investigating its effect on the production of interleukin-2 (IL-2) by CD4+ cells,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cc3eb681815640ecf3fda0710601b8c
https://pubmed.ncbi.nlm.nih.gov/10602890

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Isotretinoin and recombinant interferon alfa-2a therapy of metastatic malignant melanoma

Autor: Pierre L. Triozzi, Arthur E. Pellegrini, Michael J. Walker, Mark A. Dayton

Publikováno v: Cancer investigation. 14(4)

Twenty-five patients with metastatic malignant melanoma were treated with isotretinoin (13-cis-retinoic acid) orally at 1 mg/kg daily and recombinant interferon alfa-2a (INF-alpha) subcutaneously at 3 million units daily for 16-48 weeks. Therapy was

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97b5995a72bf2eeb0b5ce83bdf1f5bce
https://pubmed.ncbi.nlm.nih.gov/8689422

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Preleukemic state preceding adult acute lymphoblastic leukemia

Autor: Ronald Hoffman, G Tricot, Mark A. Dayton, Koen van Besien

Publikováno v: The American journal of medicine. 89(5)

A cute lymphoblastic leukemia (ALL) in adults typically presents fulminantly. However, there are numerous examples in the literature where ALL developed from an antecedent hematologic disorder. These preceding disorders include chronic granulocytic l

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::486fc95101d320d310fc0cf4cb6b899f
https://pubmed.ncbi.nlm.nih.gov/2239985

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