Zobrazeno 1 - 10
of 451
pro vyhledávání: '"Mark Lunt"'
Autor:
Mark Lunt, R B Warren, Zenas Z N Yiu, Mahmoud Zureik, Ignacio García-Doval, Emilie Sbidian, Duc Binh Phan, Hugo Jourdain, Alicia González-Quesada, Raquel Rivera-Díaz, Antonio Sahuquillo-Torralba, Miguel Angel Descalzo-Gallego
Publikováno v:
BMJ Open, Vol 13, Iss 7 (2023)
Introduction Psoriasis is a chronic inflammatory skin disease. Adalimumab is an effective but previously expensive biological treatment for psoriasis. The introduction of biosimilars following the patent expiry of the originator adalimumab Humira has
Externí odkaz:
https://doaj.org/article/60aab70842c345ee8113bc6926dca620
Modelling and classifying joint trajectories of self-reported mood and pain in a large cohort study.
Publikováno v:
PLOS Digital Health, Vol 2, Iss 3, p e0000204 (2023)
It is well-known that mood and pain interact with each other, however individual-level variability in this relationship has been less well quantified than overall associations between low mood and pain. Here, we leverage the possibilities presented b
Externí odkaz:
https://doaj.org/article/272d8f6cd1a24e908be019d5dd08cccd
Autor:
Will Dixon, Mark Lunt, Jamie C Sergeant, Arani Vivekanantham, Terence W O'Neill, Matthew J Parkes, David Selby
Publikováno v:
BMJ Open, Vol 13, Iss 3 (2023)
Objective To assess the feasibility of using smartwatches in people with knee osteoarthritis (OA) to determine the day-to-day variability of pain and the relationship between daily pain and step count.Design Observational, feasibility study.Setting I
Externí odkaz:
https://doaj.org/article/a5e5a69e5c2949dbbcc04106bb3b85cd
Publikováno v:
PLoS ONE, Vol 18, Iss 6, p e0287037 (2023)
BackgroundThe past decade has seen an explosion of research in causal mediation analysis. However, most analytic tools developed so far rely on frequentist methods which may not be robust in the case of small sample sizes. In this paper, we propose a
Externí odkaz:
https://doaj.org/article/7f2b4e341b174f839155ee1ab2c38608
Autor:
John A. Reynolds, Jennifer Prattley, Nophar Geifman, Mark Lunt, Caroline Gordon, Ian N. Bruce, on behalf of the MASTERPLANS Consortium
Publikováno v:
Arthritis Research & Therapy, Vol 23, Iss 1, Pp 1-12 (2021)
Abstract Background Systemic lupus erythematosus (SLE) is a heterogeneous systemic autoimmune condition for which there are limited licensed therapies. Clinical trial design is challenging in SLE due at least in part to imperfect outcome measures. Im
Externí odkaz:
https://doaj.org/article/7b076ac86d794548ad060875f096af9b
Autor:
Neil Solomons, Ian N Bruce, Paul Emery, Caroline Gordon, Edward Vital, David Jayne, David Isenberg, Neil McHugh, Miriam Wittmann, Stephen Young, John Reynolds, Niels Peek, Mark Lunt, Li Su, Sean Gavan, Katherine Payne, Michael Ehrenstein, Vern Farewell, Timothy Vyse, Marina Botto, David Lester Morris, D D’Cruz, Nophar Geifman, Angela Midgley, Matt Truman, Stephen McDonald, Sean Yiu, Laura Lisk, Gillian Armitt, Jennifer Prattley, Narges Azadbakht, Angela Papazian, Helen Le Sueur, Carmen Farrelly, Clare Richardson, Zunnaira Shabbir, Lauren Hewitt, Matthew Pickering, Elizabeth Lightstone, Alyssa Gilmore, Michael Beresford, Christian Hedrich, Jenna Gritzfeld, Mariea Parvaz, Jane Dunnage, Jane Batchelor, E Holland, Pauline Upsall
Publikováno v:
Lupus Science and Medicine, Vol 9, Iss 1 (2022)
Objectives To identify predictors of overall lupus and lupus nephritis (LN) responses in patients with LN.Methods Data from the Aspreva Lupus Management Study (ALMS) trial cohort was used to identify baseline predictors of response at 6 months. Endpo
Externí odkaz:
https://doaj.org/article/e8abdf0db45c48c2bc679943283668a8
Autor:
John McBeth, William G Dixon, Susan Mary Moore, Bruce Hellman, Ben James, Simon D Kyle, Mark Lunt, Lis Cordingley, Belay Birlie Yimer, Katie L Druce
Publikováno v:
Journal of Medical Internet Research, Vol 24, Iss 4, p e32825 (2022)
BackgroundSleep disturbances and poor health-related quality of life (HRQoL) are common in people with rheumatoid arthritis (RA). Sleep disturbances, such as less total sleep time, more waking periods after sleep onset, and higher levels of nonrestor
Externí odkaz:
https://doaj.org/article/0e297ca7be4747dba0bd2d734d7d5482
Autor:
Lis Cordingley, Pauline A Nelson, Linda Davies, Darren Ashcroft, Christine Bundy, Carolyn Chew-Graham, Anna Chisholm, Jamie Elvidge, Matthew Hamilton, Rachel Hilton, Karen Kane, Christopher Keyworth, Alison Littlewood, Karina Lovell, Mark Lunt, Helen McAteer, Dionysios Ntais, Rosa Parisi, Christina Pearce, Martin Rutter, Deborah Symmons, Helen Young, Christopher EM Griffiths
Publikováno v:
Programme Grants for Applied Research, Vol 10, Iss 3 (2022)
Background: Psoriasis is a common, lifelong inflammatory skin disease, the severity of which can range from limited disease involving a small body surface area to extensive skin involvement. It is associated with high levels of physical and psychosoc
Externí odkaz:
https://doaj.org/article/7e81afa6e3424642b30b0b724c0a417f
Autor:
Belay B. Yimer, David M. Schultz, Anna L. Beukenhorst, Mark Lunt, Huai L. Pisaniello, Thomas House, Jamie C. Sergeant, John McBeth, William G. Dixon
Publikováno v:
PAIN Reports, Vol 7, Iss 1, p e963 (2022)
Abstract. Introduction:. Previous studies on the association between weather and pain severity among patients with chronic pain have produced mixed results. In part, this inconsistency may be due to differences in individual pain responses to the wea
Externí odkaz:
https://doaj.org/article/7c595066c26c4556a301c68f3e7a8c89
Publikováno v:
Diagnostic and Prognostic Research, Vol 4, Iss 1, Pp 1-16 (2020)
Abstract Background Clinical prediction models (CPMs) predict the risk of health outcomes for individual patients. The majority of existing CPMs only harness cross-sectional patient information. Incorporating repeated measurements, such as those stor
Externí odkaz:
https://doaj.org/article/b6691ac2a5f84ba688bc0ec3eaff3aec