Zobrazeno 1 - 10
of 416
pro vyhledávání: '"Mark Krailo"'
Autor:
Frances Chow, Michael Berens, Sharon Tamir, Yosef Landesman, Christopher Walker, Mark Krailo, Steven Gore, Jana Portnow
Publikováno v:
Journal of Clinical and Translational Science, Vol 7, Pp 126-126 (2023)
OBJECTIVES/GOALS: Selinexor is a novel XPO1 inhibitor that blocks nuclear export, thus impairing DNA repair and causing apoptosis. Our goal was to conduct preclinical and clinical studies to test our hypothesis that selinexor’s efficacy is boosted
Externí odkaz:
https://doaj.org/article/3b387fb5faa140c6aeea72dc7a79b29e
Autor:
Lori M. Minasian, A. Lindsay Frazier, Lillian Sung, Ann O’Mara, Joseph Kelaghan, Kay W. Chang, Mark Krailo, Brad H. Pollock, Gregory Reaman, David R. Freyer
Publikováno v:
Cancer Medicine, Vol 7, Iss 7, Pp 2951-2959 (2018)
Abstract Cisplatin is an essential chemotherapeutic agent in the treatment of many pediatric cancers. Unfortunately, cisplatin‐induced hearing loss (CIHL) is a common, clinically significant side effect with life‐long ramifications, particularly
Externí odkaz:
https://doaj.org/article/7b1f627d4f434d8ea2a66c7a68b0d1e1
Publikováno v:
Journal of Cancer Survivorship. 17:4-16
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::11fa8a009714cfb511af08a5525553bd
https://doi.org/10.1007/s11764-022-01312-x
https://doi.org/10.1007/s11764-022-01312-x
Autor:
Pooja Hingorani, Mark Krailo, Allen Buxton, Paul Hutson, Paul M. Sondel, Mitchell Diccianni, Alice Yu, Carol D. Morris, Richard B. Womer, Brian Crompton, R Lor Randall, Lisa A. Teot, Steven G. DuBois, Katherine A. Janeway, Richard G. Gorlick, Michael S. Isakoff
Publikováno v:
European Journal of Cancer. 172:264-275
Novel effective therapies are urgently needed in recurrent osteosarcoma. GD2 is expressed in human osteosarcoma tumours and cell lines. This study evaluated the disease control rate (DCR) in patients with recurrent osteosarcoma treated with the anti-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf1b79debd29d05d14c7846de1615a2c
https://doi.org/10.1016/j.ejca.2022.05.035
https://doi.org/10.1016/j.ejca.2022.05.035
Autor:
Nirmish Singla, Justin Wong, Shyamli Singla, Mark Krailo, Li Huang, Furqan Shaikh, Deborah Billmire, Frederick Rescorla, Jonathon Ross, Bryan Dicken, James F. Amatruda, A. Lindsay Frazier, Aditya Bagrodia
Publikováno v:
Journal of Pediatric Urology. 18:505-511
Patients with clinical stage I (CS I: cN0M0) testicular germ cell tumors (TGCT) exhibit favorable oncologic outcomes. While prognostic features can help inform treatment in adults with CS I TGCT, we lack reliable means to predict relapse among pediat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bd464cdfc602de7749b995bd526bdba
https://doi.org/10.1016/j.jpurol.2022.04.022
https://doi.org/10.1016/j.jpurol.2022.04.022
Autor:
Katherine E. Warren, Gilbert Vezina, Mark Krailo, Linda Springer, Allen Buxton, Cody J. Peer, William D. Figg, Chris William-Hughes, Sandy Kessel, Maryam Fouladi, Amar Gajjar, Daniel Bowers
Publikováno v:
Journal of Clinical Oncology.
PURPOSE Children with low-grade glioma often require long-term therapy and suffer from treatment morbidity. Although targeted agents are promising, tumor targets often encompass normal developmental pathways and long-term effects of inhibition are un
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::500ee00913a708afa43f72b0ecb4cc29
https://doi.org/10.1200/jco.22.01777
https://doi.org/10.1200/jco.22.01777
Autor:
Shannon S. Cigan, John J. Meredith, Ava C. Kelley, Tianzhong Yang, Erica K. Langer, Anthony J. Hooten, John A. Lane, Benjamin R. Cole, Mark Krailo, A. Lindsay Frazier, Nathan Pankratz, Jenny N. Poynter
Publikováno v:
Br J Cancer
BACKGROUND: Genetically predicted leukocyte telomere length (LTL) has been evaluated in several studies of childhood and adult cancer. We test whether genetically predicted longer LTL is associated with germ cell tumours (GCT) in children and adults.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8910d2d5a2068856539cdbe4bb7015a
https://doi.org/10.1038/s41416-022-01798-3
https://doi.org/10.1038/s41416-022-01798-3
Autor:
Brenda J. Weigel, Susan M. Blaney, Stacey L. Berg, Stephan D. Voss, Mark Krailo, Donald A. Barkauskas, David Hall, Malcolm A. Smith, Peter J. Houghton, Richard B. Lock, Hernan Carol, Stephanie L. Safgren, Joel M. Reid, David T. Teachey, Elizabeth Fox, Yael P. Mossé
Purpose:Aurora A kinase (AAK) plays an integral role in mitotic entry, DNA damage checkpoint recovery, and centrosome and spindle maturation. Alisertib (MLN8237) is a potent and selective AAK inhibitor. In pediatric preclinical models, antitumor acti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f1dc91e84c94f88674693e3c59af6cb
https://doi.org/10.1158/1078-0432.c.6527514.v1
https://doi.org/10.1158/1078-0432.c.6527514.v1
Autor:
Tsz-Kwong Man, John M. Hicks, Donald A. Barkauskas, Mark Krailo, Ching C. Lau, Aaron J. Kelly, Manjula Nakka, Yiting Li
This file contains Supplementary Table S1. The clinical information of the cohort collected from Texas Children's Hospital and the cohort collected from the Children's Oncology Group Supplementary Table S2. Autoantibody candidates showed higher inten
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bd04f833beb58dc3c9c712ad18e19b1
https://doi.org/10.1158/0008-5472.22411964.v1
https://doi.org/10.1158/0008-5472.22411964.v1
Autor:
Tsz-Kwong Man, John M. Hicks, Donald A. Barkauskas, Mark Krailo, Ching C. Lau, Aaron J. Kelly, Manjula Nakka, Yiting Li
This file contains the legends of the supplementary figures.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a54610a8b60871773a64e6a14bdd023
https://doi.org/10.1158/0008-5472.22411970
https://doi.org/10.1158/0008-5472.22411970