Expression of the plasma membrane citrate carrier (pmCiC) in human cancerous tissues—correlation with tumour aggressiveness

Autor: Barbara Schwertner, George Dahdal, Wolfgang Jagla, Luis Grossmann, Konstantin Drexler, Michael P. Krahn, Katja Evert, Mark Berneburg, Sebastian Haferkamp, Christine Ziegler, Eric K. Parkinson, Grit Zahn, Maria E. Mycielska, Andreas Gaumann

Publikováno v: Frontiers in Cell and Developmental Biology, Vol 12 (2024)

We have recently shown that cancer cells of various origins take up extracellular citrate through the plasma membrane citrate carrier (pmCiC), a specific plasma membrane citrate transporter. Extracellular citrate is required to support cancer cell me

Externí odkaz: https://doaj.org/article/0e8a6ba44376475d8a649d023b9f0b09

In Vitro Safety Study on the Use of Cold Atmospheric Plasma in the Upper Respiratory Tract

Autor: Sigrid Karrer, Petra Unger, Michael Gruber, Lisa Gebhardt, Robert Schober, Mark Berneburg, Anja Katrin Bosserhoff, Stephanie Arndt

Publikováno v: Cells, Vol 13, Iss 17, p 1411 (2024)

Cold atmospheric plasma (CAP) devices generate reactive oxygen and nitrogen species, have antimicrobial and antiviral properties, but also affect the molecular and cellular mechanisms of eukaryotic cells. The aim of this study is to investigate CAP t

Externí odkaz: https://doaj.org/article/c9afa79e1fd1417084deef98fe626a89

Effect of the addition of a mental health specialist for evaluation of undiagnosed patients in centres for rare diseases (ZSE-DUO): a prospective, controlled trial with a two-phase cohort designResearch in context

Autor: Helge Hebestreit, Anne-Marie Lapstich, Lilly Brandstetter, Christian Krauth, Jürgen Deckert, Kirsten Haas, Lisa Pfister, Stefanie Witt, Christopher Schippers, Jan Dieris-Hirche, Tim Maisch, Oliver Tüscher, Lavinia Bârlescu, Alexandra Berger, Mark Berneburg, Vanessa Britz, Anna Deibele, Holm Graeßner, Harald Gündel, Gereon Heuft, Thomas Lücke, Christine Mundlos, Julia Quitmann, Frank Rutsch, Katharina Schubert, Jörg Bernhard Schulz, Susann Schweiger, Cornelia Zeidler, Lena Zeltner, Martina de Zwaan, Federica Akkaya, Christine Babka, Lisa Bannert, Anja Bärsch-Michelmann, Leonie Böhm, Folke Brinkmann, Monika Bullinger, Holger Cario, Moritz de Greck, Klaus-Michael Debatin, Katrin Dillmann-Jehn, Jutta Eymann, Julia Frisch, Anja Glode, Vega Gödecke, Corinna Grasemann, Eva Grauer, Astrid Haas, Lea Haisch, Isabell, Heinrich, Melissa Held, Julia Hennermann, Stephan Herpertz, Anne Herrmann-Werner, Julian Hett, Peter Heuschmann, Bettina Hilbig, Laura Holthöfer, Christiane Imhof, Florian Junne, Jan Kassubek, Kevin-Thomas Koschitzki, Heike Krassort, Birgit Kropff, Julia Kuhn, Philipp Latzko, Thomas Loew, Albert C. Ludolph, Torsten Meyer, Isabell Meyer dos Santos, Klaus Mohnike, Martina Monninger, Martin Mücke, Susanne Müller, Thomas Musacchio, Margret Nießen, Mariel Nöhre, Stephan Ott, Andrea Petermann-Meyer, Christina Pfeifer-Duck, Lea-Sophie Piduhn, Carina Rampp, Olaf Rieß, Kristina Schaubert, Annika Schmidt, Simone Schneider, Ludger Schoels, Martina Schwalba, Udo Selig, Alexandra Sroka, Toni Steinbüchel, Sebastian Stösser, Steffi Suchant, Kathrin Ungethüm, Matthias Vogel, Daniela Volk, Christoph Vollmuth, Solange Volnov, Thomas O.F. Wagner, Sabrina Walter, Bodo Warrings, Kamil Zajt, Karola Zenker, David Zhang, Stephan Zipfel, Lavinia Aurelia Bârlescu, Julia Hannah Quitmann, Jörg B. Schulz, Lena Margarete Zeltner

Publikováno v: EClinicalMedicine, Vol 65, Iss , Pp 102260- (2023)

Summary: Background: People with complex symptomatology but unclear diagnosis presenting to a centre for rare diseases (CRD) may present with mental (co-)morbidity. We hypothesised that combining an expert in somatic medicine with a mental health spe

Externí odkaz: https://doaj.org/article/7104fbd316dd40be90da99c4bb8c26c0

Dual guidance structure for evaluation of patients with unclear diagnosis in centers for rare diseases (ZSE-DUO): study protocol for a controlled multi-center cohort study

Autor: Helge Hebestreit, Cornelia Zeidler, Christopher Schippers, Martina de Zwaan, Jürgen Deckert, Peter Heuschmann, Christian Krauth, Monika Bullinger, Alexandra Berger, Mark Berneburg, Lilly Brandstetter, Anna Deibele, Jan Dieris-Hirche, Holm Graessner, Harald Gündel, Stephan Herpertz, Gereon Heuft, Anne-Marie Lapstich, Thomas Lücke, Tim Maisch, Christine Mundlos, Andrea Petermann-Meyer, Susanne Müller, Stephan Ott, Lisa Pfister, Julia Quitmann, Marcel Romanos, Frank Rutsch, Kristina Schaubert, Katharina Schubert, Jörg B. Schulz, Susann Schweiger, Oliver Tüscher, Kathrin Ungethüm, Thomas O. F. Wagner, Kirsten Haas, ZSE-DUO working group

Publikováno v: Orphanet Journal of Rare Diseases, Vol 17, Iss 1, Pp 1-12 (2022)

Abstract Background In individuals suffering from a rare disease the diagnostic process and the confirmation of a final diagnosis often extends over many years. Factors contributing to delayed diagnosis include health care professionals' limited know

Externí odkaz: https://doaj.org/article/e133f2dc7c254cdaa0e70f98011f467c

Degree of Actinic Elastosis Is a Surrogate of Exposure to Chronic Ultraviolet Radiation and Correlates More Strongly with Cutaneous Squamous Cell Carcinoma than Basal Cell Carcinoma

Autor: Konstantin Drexler, Hans Drexler, Sigrid Karrer, Michael Landthaler, Sebastian Haferkamp, Florian Zeman, Mark Berneburg, Dennis Niebel

Publikováno v: Life, Vol 13, Iss 3, p 811 (2023)

(1) Background: Keratinocyte cancer (KC) is associated with exposure to ultraviolet (UV) radiation. However, data are controversial as to whether chronic UV exposure or high intermittent UV exposure are key drivers of carcinogenesis in cutaneous squa

Externí odkaz: https://doaj.org/article/4ec660c8d15e40a28c9566efc1432b88