Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Markéta Rinnová"'
Publikováno v:
Tetrahedron. 65:862-876
trans-4-Hydroxy- l -proline has been used as a starting material for the synthesis of prolinol-based nucleotide analogues with an N-phosphonomethyl moiety attached to the prolinol ring nitrogen atom. The synthetic methodology based on the inversion o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f9f7676a460737733bc46e71bba1e898
https://doi.org/10.1016/j.tet.2008.11.035
https://doi.org/10.1016/j.tet.2008.11.035
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 12:3175-3178
Modulation of opioid activity was accomplished for analogues of Leu-enkephalin through incorporation of a 4-imidazolidinone moiety. The peptide backbone was constrained via a methylene bridge between two neighboring amides within its regular peptide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5812c55e534ef1e8d0da998829361fa0
https://doi.org/10.1016/s0960-894x(02)00678-9
https://doi.org/10.1016/s0960-894x(02)00678-9
Publikováno v:
Tetrahedron Letters. 43:4103-4106
The formation of α-amino phosphonate functionalities on the amino terminus of peptides utilizing solid-phase methodology is presented. The described method enables incorporation of diverse N-phosphonoalkyl and aryl moieties.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::29f8ad4d562b990134ca2541ecda0803
https://doi.org/10.1016/s0040-4039(02)00695-0
https://doi.org/10.1016/s0040-4039(02)00695-0
Publikováno v:
Tetrahedron Letters. 43:2343-2346
An efficient method for the incorporation of an imidazolidinone moiety into peptide sequences via an alkylidene bridge between two neighboring amide bonds is presented. A benzotriazole-mediated reaction of aldehydes with resin-bound peptides provides
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e5a6e93dd90cbf85de9ee82013691ee
https://doi.org/10.1016/s0040-4039(02)00263-0
https://doi.org/10.1016/s0040-4039(02)00263-0
Autor:
Pavol Kois, Jan Snášel, Šárka Králíková, Ivan Rosenberg, Markéta Rinnová, Ondřej Pačes, Radek Liboska, Dominik Rejman, Zdeněk Točík
Publikováno v:
Nucleosides, Nucleotides and Nucleic Acids. 20:819-823
Several types of isopolar modified oligothymidylates and oligoadenylates (15 mers) with the phosphonate -O-P-CH2-O- internucleotide linkage were prepared. The modified oligonucleotides were subjected to the study of their hybridization properties, re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87c8b796d170b68d91c6d66bf03441e3
https://doi.org/10.1081/ncn-100002437
https://doi.org/10.1081/ncn-100002437
Side reactions during photochemical cleavage of an ?-methyl-6-nitroveratryl-based photolabile linker
Publikováno v:
Journal of Peptide Science. 6:355-365
The mechanisms of reactions causing irreversible inhibition of the activity of enzymes when irradiated in the presence of the recently developed alpha-methyl-6-nitroveratryl-based photolinker [Holmes CP. J. Org. Chem. 1997; 62: 2370-2380] have been i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f8e1d9d4cd5382f94a24d46b9016cf0b
https://doi.org/10.1002/1099-1387(200008)6:8<355::aid-psc261>3.0.co
https://doi.org/10.1002/1099-1387(200008)6:8<355::aid-psc261>3.0.co
Publikováno v:
Letters in Peptide Science. 6:15-22
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4506f0d8580284f391f5648957f41c63
https://doi.org/10.1007/bf02443614
https://doi.org/10.1007/bf02443614
Publikováno v:
Letters in Peptide Science. 6:15-22
The condensation of short peptides to resin-bound fragments was examined with respect to high coupling yields with only a small molar excess of a peptide in the reaction solution. The best results were achieved by the addition of reactants (C-unprote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e2f2bd5dce28860c5ac3ac5a5333ea87
https://doi.org/10.1023/a:1008859225833
https://doi.org/10.1023/a:1008859225833
Autor:
Pavel Majer, Camilo Rojas, Markéta Rinnová, Pavel Šácha, Barbara S. Slusher, Jan Konvalinka, Cyril Barinka, Petra Mlčochová
Publikováno v:
Journal of Neurochemistry. 81:25-27
Glutamate carboxypeptidase II (GCPII, EC 3.4.17.21) is a membrane peptidase expressed in a number of tissues such as kidney, prostate and brain. The brain form of GCPII (also known as N-acetylated-α-linked-acidic dipeptidase, NAALADase) cleaves N-ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2e14d645d799ebe7ea182e4c0f5fc1f9
https://doi.org/10.1046/j.1471-4159.81.s1.11_1.x
https://doi.org/10.1046/j.1471-4159.81.s1.11_1.x
Autor:
Markéta Rinnová, Michal Lebl
Publikováno v:
Collection of Czechoslovak Chemical Communications. 61:171-231
Library, or molecular diversity, approaches are a progressive tool in contemporary investigation of biological interactions and drug discovery. All library approaches include certain degree of rationality and cannot be therefore classified as random
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cee9fb029296bf700bc08537eba480c3
https://doi.org/10.1135/cccc19960171
https://doi.org/10.1135/cccc19960171