Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Markéta Bébarová"'
Autor:
Samuel Lietava, Milan Sepsi, Jana Zidkova, Iva Synkova, Milan Kozak, Lubomir Krivan, Jitka Vlasinova, Svatopluk Richter, Jan Rehor, Petr Kala, Marketa Bebarova, Tomas Novotny
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-8 (2024)
Abstract Traditionally, aborted cardiac arrest (ACA) due to documented ventricular fibrillation (VF) in the absence of structural heart disease has been termed idiopathic VF. By careful evaluation, a specific etiology can be found in a substantial pr
Externí odkaz:
https://doaj.org/article/dee66629a0ec44f787a7e8cc05de5805
Autor:
Canan Celiker, Stefan Zelenak, Samuel Lietava, Jiri Pachernik, Marketa Bebarova, Jana Zidkova, Tomas Novotny, Tomas Barta
Publikováno v:
Stem Cell Research, Vol 81, Iss , Pp 103541- (2024)
Human induced pluripotent stem cell (iPSC) lines were generated from peripheral blood mononuclear cells (PBMCs) isolated from two related patients diagnosed with either idiopathic ventricular fibrillation or catecholaminergic polymorphic ventricular
Externí odkaz:
https://doaj.org/article/77ac4ee2b2ac4b0a95245b0f8e25dc88
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Sildenafil (Viagra), the first approved and widely used oral drug for the treatment of erectile dysfunction, was occasionally associated with life-threatening ventricular arrhythmias in patients. Since inward rectifier potassium current (IK1) may con
Externí odkaz:
https://doaj.org/article/b1861e74910d4693ba4e49759f037afe
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
The transverse-axial tubular system (t-tubules) plays an essential role in excitation-contraction coupling in cardiomyocytes. Its remodelling is associated with various cardiac diseases. Numerous attempts were made to analyse characteristics essentia
Externí odkaz:
https://doaj.org/article/668d4176bc62458f988676adfa93ae6e
Autor:
Iva Synková, Markéta Bébarová, Irena Andršová, Larisa Chmelikova, Olga Švecová, Jan Hošek, Michal Pásek, Pavel Vít, Iveta Valášková, Renata Gaillyová, Rostislav Navrátil, Tomáš Novotný
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract The variant c.926C > T (p.T309I) in KCNQ1 gene was identified in 10 putatively unrelated Czech families with long QT syndrome (LQTS). Mutation carriers (24 heterozygous individuals) were more symptomatic compared to their non-affected relati
Externí odkaz:
https://doaj.org/article/78136d3d7b394d9da2840cbe7a5654c8
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Sildenafil (Viagra) is a vasodilator mainly used in the treatment of erectile dysfunction. Atrial or ventricular fibrillation may rarely occur as a side effect during sildenafil therapy. Although changes in inward rectifier potassium currents includi
Externí odkaz:
https://doaj.org/article/bb2d4d2babf14c94a80ed28ee439110f
Autor:
Iva Synková, Markéta Bébarová, Irena Andršová, Larisa Chmelikova, Olga Švecová, Jan Hošek, Michal Pásek, Pavel Vít, Iveta Valášková, Renata Gaillyová, Rostislav Navrátil, Tomáš Novotný
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-3 (2021)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/7c77c1c50fb8444f9500e1f8d6f47bde
Publikováno v:
PLoS ONE, Vol 14, Iss 10, p e0223448 (2019)
Recent experimental work has revealed unusual features of the effect of certain drugs on cardiac inwardly rectifying potassium currents, including the constitutively active and acetylcholine-induced components of acetylcholine-sensitive current (IKAc
Externí odkaz:
https://doaj.org/article/cb23b234a90d4e2fb64cc7428d404a91
Autor:
Katarzyna Anna Radaszkiewicz, Dominika Sýkorová, Lucia Binó, Jana Kudová, Markéta Bébarová, Jiřina Procházková, Hana Kotasová, Lukáš Kubala, Jiří Pacherník
Publikováno v:
PLoS ONE, Vol 12, Iss 3, p e0173140 (2017)
The differentiation of pluripotent embryonic stem (ES) cells into various lineages in vitro represents an important tool for studying the mechanisms underlying mammalian embryogenesis. It is a key technique in studies evaluating the molecular mechani
Externí odkaz:
https://doaj.org/article/4c24f865053945c683e5f4b9f4f65f94
Publikováno v:
Progress in Biophysics and Molecular Biology. 157:11-17
The distribution of data presented in many electrophysiological studies is presumed to be normal without any convincing evidence. To test this presumption, the cell membrane capacitance and magnitude of inward rectifier potassium currents were record