Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Mark, de Caestecker"'
Autor:
Min Yang, Lauren N. Lopez, Maya Brewer, Rachel Delgado, Anna Menshikh, Kelly Clouthier, Yuantee Zhu, Thitinee Vanichapol, Haichun Yang, Raymond C. Harris, Leslie Gewin, Craig R. Brooks, Alan J. Davidson, Mark de Caestecker
Publikováno v:
JCI Insight, Vol 8, Iss 20 (2023)
Retinoic acid receptor (RAR) signaling is essential for mammalian kidney development but, in the adult kidney, is restricted to occasional collecting duct epithelial cells. We now show that there is widespread reactivation of RAR signaling in proxima
Externí odkaz:
https://doaj.org/article/1352fa0980e64b42b36f87f9d4c8e2ab
Autor:
Corina M. Borza, Gema Bolas, Fabian Bock, Xiuqi Zhang, Favour C. Akabogu, Ming-Zhi Zhang, Mark de Caestecker, Min Yang, Haichun Yang, Ethan Lee, Leslie Gewin, Agnes B. Fogo, W. Hayes McDonald, Roy Zent, Ambra Pozzi
Publikováno v:
JCI Insight, Vol 7, Iss 3 (2022)
Discoidin domain receptor 1 (DDR1), a receptor tyrosine kinase activated by collagen, contributes to chronic kidney disease. However, its role in acute kidney injury and subsequent development of kidney fibrosis is not clear. Thus, we performed a mod
Externí odkaz:
https://doaj.org/article/6f07acb1dfff4ac28df80270a5448e12
Autor:
Keith Long, Zoe Vaughn, Michael David McDaniels, Sipak Joyasawal, Aneta Przepiorski, Emily Parasky, Veronika Sander, David Close, Paul A. Johnston, Alan J. Davidson, Mark de Caestecker, Neil A. Hukriede, Donna M. Huryn
Publikováno v:
ACS Pharmacol Transl Sci
[Image: see text] Acute kidney injury (AKI), a sudden loss of kidney function, is a common and serious condition for which there are no approved specific therapies. While there are multiple approaches to treat the underlying causes of AKI, no targets
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bb62d77d60c78abb1266f29192965aa
https://doi.org/10.1021/acsptsci.1c00243
https://doi.org/10.1021/acsptsci.1c00243
Autor:
Janene Pierce, Andrew J. Murphy, Alexis Panzer, Christian de Caestecker, Gregory D. Ayers, David Neblett, Kenyi Saito-Diaz, Mark de Caestecker, Harold N. Lovvorn, III
Publikováno v:
Translational Oncology, Vol 7, Iss 6, Pp 800-811 (2014)
Wilms tumor (WT) blastema retains gene expression profiles characteristic of the multipotent nephron progenitor pool, or cap mesenchyme (CM), in the developing kidney. As a result, WT blastema and the CM are believed to represent contextual analogues
Externí odkaz:
https://doaj.org/article/2ecb52cfd93c45468736f3c586d7f5ba
Autor:
Maya Brewer, Jamie Allen, Carrie Romer, Elizabeth Neumann, Agnes Fogo, Raymond Harris, Danielle Gutierrez, Mark De Caestecker, Jeff Spraggins
Scope: Obtain kidney tissue and metadata about tissue location within the whole kidney for storage and analysis. Expected Outcome: A portion of kidney tissue and a series of images that provide information about the original location of the smaller t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::695a707cbea6ee2ea8a1e20812778295
https://doi.org/10.17504/protocols.io.buggnttw
https://doi.org/10.17504/protocols.io.buggnttw
Autor:
Elizabeth Neumann, Jamie Allen, Jennifer Harvey, Maya Brewer, Carrie Romer, Mark De Caestecker, Jeff Spraggins
Scope: The PAS stain is used to demonstrate polysaccharides such as glycogen, and mucosubstances such as glycoproteins, glycolipids and mucins in tissues. It is used as a replacement for the H&E in kidney pathology. Expected Outcome: Intermyofibrilla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::65e7dae68f4fa77f8b0e85ad77dedb0a
https://doi.org/10.17504/protocols.io.buaknscw
https://doi.org/10.17504/protocols.io.buaknscw
Autor:
Maya Brewer, Liz McDonough, Yuantee Zhu, Elizabeth Neumann, Mark De Caestecker, Danielle Gutierrez, Jeff Spraggins
Scope: To describe the procedure for multiple cycles of immunofluorescence on human kidney tissue embedded in carboxymethylcellulose. Expected Outcome: Kidney tissue sections that have been tagged with antibodies for imaging microscopy.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a915c5821a80d146a3fc67bd6827b1a4
https://doi.org/10.17504/protocols.io.bs68nhhw
https://doi.org/10.17504/protocols.io.bs68nhhw
Publikováno v:
Seminars in Nephrology. 42:151275
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d953da7b6648f811f9011e6b76e67fa
https://doi.org/10.1016/j.semnephrol.2022.10.001
https://doi.org/10.1016/j.semnephrol.2022.10.001
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e80319 (2013)
More than 200 heterozygous mutations in the type 2 BMP receptor gene, BMPR2, have been identified in patients with Heritable Pulmonary Arterial Hypertension (HPAH). More severe clinical outcomes occur in patients with BMPR2 mutations by-passing nonse
Externí odkaz:
https://doaj.org/article/7ecfeda5961f490b8caeca0d72db0060
Autor:
Elizabeth Neumann, Jamie Allen, Maya Brewer, David Anderson, Mark De Caestecker, Danielle Gutierrez, Jeff Spraggins
We aim to develop high resolution, chemically informative imaginig methodologies for building an atlas of human organs, such as the kidney. Scope: Provide an overview of the methods used by the Vanderbilt Tissue Mapping Center as part of the Human Bi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d0ef9cd795550e7b1186d4712a684655
https://doi.org/10.17504/protocols.io.bfskjncw
https://doi.org/10.17504/protocols.io.bfskjncw