Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Mark, Turlington"'
Autor:
Erin E. Ramey, Elizabeth L. Whitman, Cole E. Buller, James R. Tucker, Charles S. Jolly, Kjersti G. Oberle, Austin J. Becksvoort, Mark Turlington, Christopher R. Turlington
Publikováno v:
Polymers, Vol 15, Iss 9, p 2052 (2023)
Biodegradable polymers are desirable to mitigate the environmental impact of plastic waste in the environment. Over the past several decades, the development of organocatalytic ring-opening polymerization (OROP) has made the synthesis of many new typ
Externí odkaz:
https://doaj.org/article/83453457817d447baaa23971a8ab5100
Autor:
Kjersti G. Oberle, Elizabeth L. Whitman, Charles S. Jolly, Katherine A. Webster, Benjamin S. Marx, Christopher M. Howard, Clara A. Hanger, Erin E. Ramey, Yutong Zou, Jared C. Lowe, Mark Turlington, Christopher R. Turlington
Publikováno v:
Polymer Chemistry. 13:4747-4751
Organocatalytic ring-opening polymerization of cyclic carbonate monomers derivatized with metallocenes is described for the rapid synthesis of high Mn metallopolymers.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8e5c1052aeafb330210e69689e5f17d2
https://doi.org/10.1039/d2py00747a
https://doi.org/10.1039/d2py00747a
Autor:
Harrison M. Hill, Charles S. Jolly, Savannah J. Post, Emma Kochanowski, Mark Turlington, Cayden J. Dodd
Publikováno v:
The Journal of Organic Chemistry. 86:2667-2681
The stereoselective synthesis of terminal bromo-substituted propargylamines via in situ generation of lithium bromoacetylide from 1,2-dibromoethene and addition to Ellman chiral N-tert-butanesulfinyl aldimines is reported. Modest to good yields (43-8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::477418d162f58abb5039b0303c38576b
https://doi.org/10.1021/acs.joc.0c02697
https://doi.org/10.1021/acs.joc.0c02697
Autor:
Han Zhou, Tomaya Carpenter, Xuan Fu, Bo Jin, Britton Ody, Mohammad Sazid Hassan, Savannah E. Jacobs, Jenny Cheung, Eve M. Nicholson, Mark Turlington, Bo Zhao, Sonja Lorenz, T. Ashton Cropp, Jun Yin
Publikováno v:
ChemBioChem. 23
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9e52fa9ff3b9c41ad74cd7c47ce01153
https://doi.org/10.1002/cbic.202200226
https://doi.org/10.1002/cbic.202200226
Autor:
Han Zhou, Tomaya Carpenter, Xuan Fu, Bo Jin, Britton Ody, Mohammad Sazid Hassan, Savannah E. Jacobs, Jenny Cheung, Eve M. Nicholson, Mark Turlington, Bo Zhao, Sonja Lorenz, T. Ashton Cropp, Jun Yin
Publikováno v:
Chembiochem
Di-ubiquitin (diUB) conjugates of defined linkages are useful tools to probe the functions of UB ligases, UB-binding proteins and deubiquitinating enzymes (DUBs) in coding, decoding and editing the signals carried by the UB chains. Here we developed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6471e46d8d79a879936afcc31eb607c8
https://pubmed.ncbi.nlm.nih.gov/35567288
https://pubmed.ncbi.nlm.nih.gov/35567288
Autor:
Kenneth L. Martin, Mark Turlington, Jake E. Doiron, Stephen G. Aller, Gary W. Breton, John Bacsa, Christina A. Le
Publikováno v:
ChemMedChem. 15:1720-1730
Although the 1,2,3-triazole is a commonly used amide bioisostere in medicinal chemistry, the structural implications of this replacement have not been fully studied. Employing X-ray crystallography and computational studies, we report the spatial and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb48cfb8491ca9fda7b1fe09420a98b8
https://doi.org/10.1002/cmdc.202000220
https://doi.org/10.1002/cmdc.202000220
Autor:
Charles S, Jolly, Emma, Kochanowski, Cayden J, Dodd, Savannah J, Post, Harrison M, Hill, Mark, Turlington
Publikováno v:
The Journal of organic chemistry. 86(3)
The stereoselective synthesis of terminal bromo-substituted propargylamines via
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5a7fd029448139d67578e5758d88db3a
https://pubmed.ncbi.nlm.nih.gov/33448846
https://pubmed.ncbi.nlm.nih.gov/33448846
Publikováno v:
Tetrahedron Letters. 58:470-473
A general approach for the stereoselective synthesis of 2-substituted 1,2,5,6-tetrahydropyridines and piperidines is described. The addition of 4-chloro-1-butyne to Ellman sulfinimines to produce chloro-containing propargylamines, reduction with Lind
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::342e186945508e987559947d976dd903
https://doi.org/10.1016/j.tetlet.2016.12.061
https://doi.org/10.1016/j.tetlet.2016.12.061
Autor:
Savannah J. Post, Liping Tang, Matthew J. Mulder, Christina A. Le, Mark Turlington, Stephen G. Aller, Steven M. Rowe, Gary W. Breton, Sichen Chang, Britton K. Ody, Jonathon B. Brace, Jake E. Doiron, Harrison M. Hill, Wei Wang, Nathan L. Thacker, Thomas M. Bridges
Publikováno v:
Chemistry (Weinheim an der Bergstrasse, Germany). 25(14)
The 1,2,3-triazole has been successfully utilized as an amide bioisostere in multiple therapeutic contexts. Based on this precedent, triazole analogues derived from VX-809 and VX-770, prominent amide-containing modulators of the cystic fibrosis trans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3e74072f169b81c8dc63a7e650da7af
https://pubmed.ncbi.nlm.nih.gov/30650214
https://pubmed.ncbi.nlm.nih.gov/30650214
Autor:
José Manuel Bartolomé-Nebreda, Thomas Steckler, Susana Conde-Ceide, Colleen M. Niswender, Chrysa Malosh, María Piedrafita, Meredith J. Noetzel, Claire Mackie, Paige N. Vinson, Jerri M. Rook, Gregor James Macdonald, M. Rosa Sánchez-Casado, P. Jeffrey Conn, Shaun R. Stauffer, Carlos M. Martínez-Viturro, Hilde Lavreysen, J. Scott Daniels, Carrie K. Jones, Mark Turlington, Thomas M. Bridges, Craig W. Lindsley
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 25:5115-5120
We report the optimization of a series of metabotropic glutamate receptor 5 (mGlu5) positive allosteric modulators (PAMs) from an acyl dihydropyrazolo[1,5-a]pyrimidinone class. Investigation of exocyclic amide transpositions with this unique 5,6-bicy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b8088322559a22014da4ba8a0d907b9
https://doi.org/10.1016/j.bmcl.2015.10.009
https://doi.org/10.1016/j.bmcl.2015.10.009