Výsledky vyhledávání - "Mark, Smithies"

Clinically practical blood volume assessment with fluorescein-labeled HES

Autor: Ceri Phillips, G. P. Findlay, Edwin Massey, Paul Spark, Sanjoy Shah, Mark Smithies, C Wardrop, G.T. Robinson, Robert G. Newcombe, Pamela de Souza

Publikováno v: Transfusion. 44:151-157

BACKGROUND: Standard techniques for measuring blood volume (BV) entail administering radioactivity and human albumin. This is laborious, expensive, and impractical in acute settings. An alternative method suitable for widespread routine application w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3be82d3ffdb48a802b6b9c9b45b2147b
https://doi.org/10.1111/j.1537-2995.2004.00637.x

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Cardiovascular effects of the nitric oxide synthase inhibitor NG-methyl-l-arginine hydrochloride (546C88) in patients with septic shock: Results of a randomized, double-blind, placebo-controlled multicenter study (study no. 144-002)*

Autor: Kalpalatha K. Guntupalli, Rinaldo Bellomo, José A. Lorente, Mark Smithies, Jill Donaldson, Steven H. Grossman, Jean Roger Le Gall, David Watson, Antonio Anzueto, Robert Grover

Publikováno v: Critical Care Medicine. 32:13-20

Objective To assess the hemodynamic effects of the nitric oxide synthase inhibitor 546C88 in patients with septic shock, although this was not a stated aim of the protocol. The predefined primary efficacy objective of the protocol was resolution of s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8ee0561819b8b308e32be22f16d1ba67
https://doi.org/10.1097/01.ccm.0000104209.07273.fc

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Tracheal gas insufflation

Autor: John Dingley, Mark Smithies, R. King, Bernard A Foëx, G. P. Findlay, Roderick A. Little

Publikováno v: Anaesthesia. 56:433-440

Tracheal gas insufflation is a technique in which gas is injected intratracheally during positive pressure ventilation. The fresh gas rinses expired gas from the tracheal tube and anatomical dead space, aiding carbon dioxide elimination. This reduces

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4885a855246bbc0a58e32dfe3931f771
https://doi.org/10.1046/j.1365-2044.2001.01909.x

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The diagnosis of ventilator-associated pneumonia using non-bronchoscopic, non-directed lung lavages

Autor: Mark Smithies, J. T. Magee, A. Ionescu, Rosemary Ann Barnes, G. P. Findlay, P. G. Flanagan

Publikováno v: Intensive Care Medicine. 26:20-30

Objectives: (1)To assess the diagnostic utility of quantitative cultures of non-bronchoscopic lung lavage (NBL) in ventilator-associated pneumonia and evaluate the role of the Bacterial Index; (2) To assess the predictive value of NBL surveillance qu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45ec23588e2809e69b1308e22351feaa
https://doi.org/10.1007/s001340050007

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Inhalation of nitric oxide in acute lung injury: results of a European multicentre study

Autor: H. Mang, Stefan Lundin, Ola Stenqvist, Mark Smithies, Claes Frostell

Publikováno v: Intensive Care Medicine. 25:911-919

Objective: To determine whether inhalation of nitric oxide (INO) can increase the frequency of reversal of acute lung injury (ALI) in nitric oxide (NO) responders. Design: Prospective, open, randomised, multicentre, parallel group phase III trial. Se

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ad1f1e7874b0a8166337862dc1d7ee24
https://doi.org/10.1007/s001340050982

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ABC of intensive care: Organ dysfunction

Autor: Timothy W Evans, Mark Smithies

Publikováno v: BMJ. 318:1606-1609

Timothy W Evans is professor of intensive care medicine, Imperial College School of Medicine, Royal Brompton Hospital, London and Mark Smithies is director of intensive care, University Hospital of Wales, Cardiff.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9856223054c7f574b3a1d775073fdc37
https://doi.org/10.1136/bmj.318.7198.1606

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Cerebral blood flow is proportional to cardiac index in patients with septic shock

Autor: David Bihari, Mark Smithies, Kamran B. Modaresi, Stephen M. Smith, Soundrie Padayachee

Publikováno v: Journal of Critical Care. 13:104-109

Purpose: In patients with septic shock, the cardiac index is often increased. Maldistribution of blood flow and regional hypoperfusion has been implicated as a key factor in the pathogenesis of organ dysfunction in these patients. We have investigate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19563c5cab563092fe07afe6b066200e
https://doi.org/10.1016/s0883-9441(98)90013-2

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Liver Function and Splanchnic Ischemia in Critically III Patients

Autor: Mark Smithies, Nicholas Maynard, R. Neil Dalton, R C Mason, Richard Beale, David Bihari

Publikováno v: Chest. 111:180-187

To investigate the concept that splanchnic ischemia leads to hepatic dysfunction in the critically ill.Prospective study and analysis of patient data.A general ICU in an inner-city London teaching hospital.Twenty-seven consecutive critically ill pati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::864f7756a1bf37a91ec168d27aced594
https://doi.org/10.1378/chest.111.1.180

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