Zobrazeno 1 - 10
of 367
pro vyhledávání: '"Mark, Simpson"'
Autor:
Sarah M. Hammoudeh, Yeap Ng, Bih-Rong Wei, Thomas D. Madsen, Mukesh P. Yadav, R. Mark Simpson, Roberto Weigert, Paul A. Randazzo
Publikováno v:
Cell Reports: Methods, Vol 4, Iss 7, Pp 100802- (2024)
Summary: PAX3/7 fusion-negative rhabdomyosarcoma (FN-RMS) is a childhood mesodermal lineage malignancy with a poor prognosis for metastatic or relapsed cases. Limited understanding of advanced FN-RMS is partially attributed to the absence of sequenti
Externí odkaz:
https://doaj.org/article/de21190a5a7242a48483a45be5f5303c
Publikováno v:
Frontiers in Neurology, Vol 15 (2024)
BackgroundAccelerometers are commonly used for the assessment of PA; however, these devices have not been validated in people with dystonia who experience movement limitations. To properly understand movement behaviors and deliver accurate exercise p
Externí odkaz:
https://doaj.org/article/8ec2ed880f02413cac3190d03f38f870
Autor:
Pooja Swali, Rick Schulting, Alexandre Gilardet, Monica Kelly, Kyriaki Anastasiadou, Isabelle Glocke, Jesse McCabe, Mia Williams, Tony Audsley, Louise Loe, Teresa Fernández-Crespo, Javier Ordoño, David Walker, Tom Clare, Geoff Cook, Ian Hodkinson, Mark Simpson, Stephen Read, Tom Davy, Marina Silva, Mateja Hajdinjak, Anders Bergström, Thomas Booth, Pontus Skoglund
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-9 (2023)
Abstract Extinct lineages of Yersinia pestis, the causative agent of the plague, have been identified in several individuals from Eurasia between 5000 and 2500 years before present (BP). One of these, termed the ‘LNBA lineage’ (Late Neolithic and
Externí odkaz:
https://doaj.org/article/2a08205a91084a63832f85f8236c0da5
Starting with an overview of the development of money laundering and the work of international organisations, International Guide to Money Laundering Law and Practice is a unique publication providing a detailed insight into the background of money l
Autor:
Mark Simpson, Melissa T Baysari, Steven M McPhail, Tim J Shaw, Adeola Bamgboje-Ayodele, David Brain, Richard Taggart, Mitchell Burger, Lenert Bruce, Caroline Holtby, Malcolm Pradhan
Publikováno v:
BMJ Open, Vol 13, Iss 11 (2023)
Objectives Digital health is now routinely being applied in clinical care, and with a variety of clinician-facing systems available, healthcare organisations are increasingly required to make decisions about technology implementation and evaluation.
Externí odkaz:
https://doaj.org/article/a9fc65e6b2ca49cc83f20a0740f0f0b9
Autor:
Corrinne Harol, Mark Simpson
In Literary/Liberal Entanglements, Corrinne Harol and Mark Simpson bring together ten essays by scholars from a wide range of fields in English studies in order to interrogate the complex, entangled relationship between the history of literature and
Autor:
Ruhul Amin, Anjali Shukla, Jacqueline Jufen Zhu, Sohyoung Kim, Ping Wang, Simon Zhongyuan Tian, Andy D. Tran, Debasish Paul, Steven D. Cappell, Sandra Burkett, Huaitian Liu, Maxwell P. Lee, Michael J. Kruhlak, Jennifer E. Dwyer, R. Mark Simpson, Gordon L. Hager, Yijun Ruan, Kent W. Hunter
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-23 (2021)
The involvement of nuclear pore proteins in cellular mechanosensing and metastasis is unclear. Here the authors identify that nuclear pore protein NUP210 promotes metastasis through the interaction with mechanotransducer LINC complex protein and chro
Externí odkaz:
https://doaj.org/article/53398503c4ff4121a84866fffaede387
Autor:
Bih-Rong Wei, Cody J. Peer, William J. Richardson, Stephen M. Hewitt, William D. Figg, R. Mark Simpson
Publikováno v:
Frontiers in Veterinary Science, Vol 9 (2022)
Activation of one or both the Ras/MAPK and PI3K/Akt/mTOR signal transduction pathways are known to mediate oncogenicity of several canine and human cancers, including mucosal melanomas. Reciprocal cross activation between the two pathways can be a so
Externí odkaz:
https://doaj.org/article/b3aa62de85994eb88e051c19e87a5dbd
Autor:
Tsung-Po Lai, Mark Simpson, Krunal Patel, Simon Verhulst, Jungsik Noh, Natalie Roche, Debra Heller, George Guirguis, Jerry W. Shay, Utz Herbig, Abraham Aviv
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Recent hypotheses propose that the human placenta and chorioamniotic membranes (CAMs) experience telomere length (TL)-mediated senescence. These hypotheses are based on mean TL (mTL) measurements, but replicative senescence is triggered by s
Externí odkaz:
https://doaj.org/article/13552a04d1b744908ff53b255f946d51
Autor:
Vanesa C Sanchez, Howard H Yang, Alayna Craig-Lucas, Wendy Dubois, Brandi L Carofino, Justin Lack, Jennifer E Dwyer, R Mark Simpson, Christophe Cataisson, Max P Lee, Ji Luo, Kent W Hunter, Stuart H Yuspa
Publikováno v:
PLoS Genetics, Vol 18, Iss 6, p e1010271 (2022)
The TGF-β-regulated Chloride Intracellular Channel 4 (CLIC4) is an essential participant in the formation of breast cancer stroma. Here, we used data available from the TCGA and METABRIC datasets to show that CLIC4 expression was higher in breast ca
Externí odkaz:
https://doaj.org/article/a8c9af69453d42e7a8a1e57bff679371