Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Mark, Rekhter"'
Autor:
Ming-Shang Kuo, J. Michael Kalbfleisch, Pamela Rutherford, Donetta Gifford-Moore, Xiao-di Huang, Robert Christie, Kwan Hui, Kenneth Gould, Mark Rekhter
Publikováno v:
Journal of Lipid Research, Vol 49, Iss 6, Pp 1353-1363 (2008)
Sensitive method for chemical analysis of free cholesterol (FC) and cholesterol esters (CE) was developed. Mouse arteries were dissected and placed in chloroform-methanol without tissue grinding. Extracts underwent hydrolysis of cholesteryl esters an
Externí odkaz:
https://doaj.org/article/28858096bce742e5a9c18b847f04ed72
Autor:
Kevin Duffin, Kwan Hui, Donetta Gifford-Moore, Xiao-di Huang, Pamela G Rutherford, Nancy K Jackson, John E Hale, Li-Chun Chio, Eugene Zhen, Richard E Higgs, Shuguang Huang, Chung-Wein Lee, Karen Cox, Eileen McCall, Birong Liao, Kenneth E Gould, Mark Rekhter
Publikováno v:
Biomarker Insights, Vol 3, Pp 147-157 (2008)
Background: Current drug therapy of atherosclerosis is focused on treatment of major risk factors, e.g. hypercholesterolemia while in the future direct disease modification might provide additional benefits. However, development of medicines targetin
Externí odkaz:
https://doaj.org/article/c60e5078af034c7d87387ef96cc610fb
Autor:
Birong Liao, Eileen McCall, Karen Cox, Chung-Wein Lee, Shuguang Huang, Richard E Higgs, Li-Chun Chio, Eugene Zhen, John E Hale, Nancy K Jackson, Pamela G Rutherford, Xiao-di Huang, Donetta Gifford-Moore, Kwan Hui, Kevin Duffin, Kenneth E Gould, Mark Rekhter
Publikováno v:
Biomarker Insights, Vol 3 (2008)
Background Current drug therapy of atherosclerosis is focused on treatment of major risk factors, e.g. hypercholesterolemia while in the future direct disease modification might provide additional benefits. However, development of medicines targeting
Externí odkaz:
https://doaj.org/article/77cc1c7dae3b422aab289767ebbbcbd2
Autor:
Christian Rask-Madsen, George L. King, Kyoungmin Park, Erica L. Buonomo, Qian Li, Allen C. Clermont, Oluwatobi Yerokun, Mark Rekhter
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 32:1124-1131
Objective— To determine the contribution of hyperinsulinemia to atherosclerosis development. Methods and Results— Apolipoprotein E ( Apoe ) null mice that had knockout of a single allele of the insulin receptor ( Insr ) gene were compared with li
Autor:
Mark Rekhter, Charles Reidy, Ming-Shang Kuo, Pamela Rutherford, Patricia S. Foxworthy, Nancy K Jackson, Kirk A. Staschke, Kwan Hui, Chris J. Vlahos, Michael Kalbfleisch, Donetta Gifford-Moore, Xiao-di Huang, Thomas B. Estridge, Raymond Gilmour
Publikováno v:
Biochemical and Biophysical Research Communications. 367:642-648
Inflammation is critically involved in atherogenesis. Signaling from innate immunity receptors TLR2 and 4, IL-1 and IL-18 is mediated by MyD88 and further by interleukin-1 receptor activated kinases (IRAK) 4 and 1. We hypothesized that IRAK4 kinase a
Autor:
Ryan E Feaver, Mark Rekhter, Sandi Walton, Nathan Day, Jorge Alsina-Fernandez, Mark Kowala, Brian Wamhoff, Brett Blackman
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 33
Glucagon-like peptide-1(GLP-1), an incretin hormone, has been shown to have atheroprotective effects on the cardiovascular system in animal models of atherosclerosis and diabetes, and in several clinical trials. These beneficial effects are presumed
Publikováno v:
Journal of biomedical optics. 12(5)
Structural proteins such as elastin and collagen can be readily imaged by using two-photon excitation and second-harmonic generation microscopic techniques, respectively, without physical or biochemical processing of the tissues. This time- and effor
Autor:
Mark, Rekhter, Kaarthik, Chandrasekhar, Donetta, Gifford-Moore, Xiao-di, Huang, Pamela, Rutherford, Jeffrey, Hanson, Raymond, Kauffman
Publikováno v:
Experimental and clinical cardiology. 12(4)
The pleiotropic antiatherosclerotic effects of statins are believed to be associated with the inhibition of Rho-kinase. However, a systematic analysis of Rho-kinase activation in atherosclerotic lesions is missing.To analyze the distribution and phos
Autor:
Li-Chun Chio, Shuguang Huang, Kevin L. Duffin, Xiao-di Huang, Kwan Hui, Chung-Wein Lee, Mark Rekhter, Eugene Zhen, Pamela Rutherford, Birong Liao, Eileen McCall, Donetta Gifford-Moore, Nancy K Jackson, Gould Kenneth Elliot, Karen Cox, Richard E. Higgs, John E. Hale
Publikováno v:
Biomarker Insights, Vol 3 (2008)
Biomarker Insights
Biomarker Insights, Vol 3, Pp 147-157 (2008)
Biomarker Insights
Biomarker Insights, Vol 3, Pp 147-157 (2008)
Background Current drug therapy of atherosclerosis is focused on treatment of major risk factors, e.g. hypercholesterolemia while in the future direct disease modification might provide additional benefits. However, development of medicines targeting
Autor:
Mark Rekhter
Publikováno v:
Current Opinion in Cardiology; Nov2002, Vol. 17 Issue 6, p626-632, 7p