Zobrazeno 1 - 10
of 148
pro vyhledávání: '"Mark, Nitz"'
Autor:
Erum Razvi, Benjamin R. DiFrancesco, Gregory A. Wasney, Zachary A. Morrison, John Tam, Anick Auger, Perrin Baker, Noor Alnabelseya, Jacquelyn D. Rich, Piyanka Sivarajah, Gregory B. Whitfield, Joe J. Harrison, Roman A. Melnyk, Mark Nitz, P. Lynne Howell
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 3 (2023)
ABSTRACT Biosynthesis of the Pel exopolysaccharide in Pseudomonas aeruginosa requires all seven genes of the pelABCDEFG operon. The periplasmic modification enzyme PelA contains a C-terminal deacetylase domain that is necessary for Pel-dependent biof
Externí odkaz:
https://doaj.org/article/b1f3f3737eb946da81f5127f4eeb2e68
Autor:
Roland Pfoh, Adithya S Subramanian, Jingjing Huang, Dustin J Little, Adam Forman, Benjamin R DiFrancesco, Negar Balouchestani-Asli, Elena N Kitova, John S Klassen, Régis Pomès, Mark Nitz, P Lynne Howell
Publikováno v:
PLoS Pathogens, Vol 18, Iss 8, p e1010750 (2022)
The synthesis of exopolysaccharides as biofilm matrix components by pathogens is a crucial factor for chronic infections and antibiotic resistance. Many periplasmic proteins involved in polymer processing and secretion in Gram-negative synthase depen
Externí odkaz:
https://doaj.org/article/a4e5e4ac72e544bdb741f717ccff0750
Autor:
Shuya Kate Huang, Omar Almurad, Reizel J Pejana, Zachary A Morrison, Aditya Pandey, Louis-Philippe Picard, Mark Nitz, Adnan Sljoka, R Scott Prosser
Publikováno v:
eLife, Vol 11 (2022)
Cholesterol is a major component of the cell membrane and commonly regulates membrane protein function. Here, we investigate how cholesterol modulates the conformational equilibria and signaling of the adenosine A2A receptor (A2AR) in reconstituted p
Externí odkaz:
https://doaj.org/article/7e161692e49f49248619e079af5b4977
Autor:
Loryn P. Arnett, Rahul Rana, Wilson Wai-Yip Chung, Xiaochong Li, Mahtab Abtahi, Daniel Majonis, Jay Bassan, Mark Nitz, Mitchell A. Winnik
Publikováno v:
Chemical Reviews. 123:1166-1205
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e06e0cc50649edd2a6803ceede2e950a
https://doi.org/10.1021/acs.chemrev.2c00350
https://doi.org/10.1021/acs.chemrev.2c00350
Autor:
Jay Bassan, Mark Nitz
Publikováno v:
PLoS ONE, Vol 14, Iss 9, p e0221714 (2019)
Imaging mass cytometry (IMC) is a technique allowing visualization and quantification of over 40 biological parameters in a single experiment with subcellular spatial resolution, however most IMC experiments are limited to endpoint analysis with anti
Externí odkaz:
https://doaj.org/article/8e9858db6e274b518bb72ae44d12470e
Autor:
Zachary A. Morrison, Alexander Eddenden, Adithya Shankara Subramanian, P. Lynne Howell, Mark Nitz
Publikováno v:
ACS Chemical Biology. 17:3036-3046
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d3855ae9529e1c665e9c9028309b782d
https://doi.org/10.1021/acschembio.1c00855
https://doi.org/10.1021/acschembio.1c00855
Autor:
Carmanah Hunter, Zhizeng Gao, Hong-Ming Chen, Nicole Thompson, Warren Wakarchuk, Mark Nitz, Stephen G. Withers, Lisa M. Willis
Publikováno v:
ACS chemical biology.
Sialic acids are key mediators of cell function, particularly with regards to cellular interactions with the surrounding environment. Reagents that modulate the display of specific sialyl glycoforms at the cell surface would be useful biochemical too
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fab363550b293c98614849dad5cf4ef
https://pubmed.ncbi.nlm.nih.gov/36577399
https://pubmed.ncbi.nlm.nih.gov/36577399
Autor:
Dustin J Little, Roland Pfoh, François Le Mauff, Natalie C Bamford, Christina Notte, Perrin Baker, Manita Guragain, Howard Robinson, Gerald B Pier, Mark Nitz, Rajendar Deora, Donald C Sheppard, P Lynne Howell
Publikováno v:
PLoS Pathogens, Vol 14, Iss 4, p e1006998 (2018)
Poly-β(1,6)-N-acetyl-D-glucosamine (PNAG) is a major biofilm component of many pathogenic bacteria. The production, modification, and export of PNAG in Escherichia coli and Bordetella species require the protein products encoded by the pgaABCD opero
Externí odkaz:
https://doaj.org/article/eb91361e84b14e24a860218a28db4e5a
Autor:
Mark Nitz, Petra Vlckova, Jahangir Sufi, Christopher J. Tape, Xiao Qin, Yong Jia Bu, Ferran Cardoso Rodriguez, María Ramos Zapatero
Publikováno v:
Nature Protocols. 16:4897-4918
Organoids are biomimetic tissue models comprising multiple cell types and cell states. Post-translational modification (PTM) signaling networks control cellular phenotypes and are frequently dysregulated in diseases such as cancer. Although signaling
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53a92bd2c0071785f025877718c7a5a2
https://doi.org/10.1038/s41596-021-00603-4
https://doi.org/10.1038/s41596-021-00603-4
Autor:
Daniel Lee, Simon Latour, Michael Emblem, Jobette Santos, Jaewan Jang, Alison McGuigan, Mark Nitz
Aldehydes are attractive bioorthogonal coupling partners. The ease of manipulation of aldehydes and their orthogonality to other classes of bioorthogonal reactions has inspired the exploration of chemistries which generate irreversible conjugates. Si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9d0529dda5ec0fb2a9b4650121f0ea87
https://doi.org/10.26434/chemrxiv-2022-bk73l-v2
https://doi.org/10.26434/chemrxiv-2022-bk73l-v2
