IL-1β and IL-1ra are key regulators of the inflammatory response to RNA vaccines

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Excessive systemic inflammation is characteristic to various acute conditions including sepsis, viral infections and immunotherapy-induced adverse events such as cytokine release syndrome (CRS). Recently, several clinical trials evaluating variants o

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https://doi.org/10.21203/rs.3.rs-378991/v1

183 Safe neurological services: how should we best measure safety in neurology practice in the UK?

Autor: Christopher Kipps, Lucy Kinton, Mark McCarron, Arani Nitkunan, Kate Petheram, Amy Ross-Russell, Anand Tripp, Graham Warner, Angelika Zarkali

Publikováno v: Journal of Neurology, Neurosurgery & Psychiatry. 93:A65.3-A65

Patient safety has been recognised as a top global priority. Safe neurological practice is crucial. Yet, how do we adequately measure safety in our services? A range of standpoints need to be considered including safety at clinician level, safety wit

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https://doi.org/10.1136/jnnp-2022-abn.212

268 Predicting large vessel occlusion using non-contrast CT brain in patients with acute stroke

Autor: Ferghal Mcverry, Gavin McCluskey, Elizabeth Best, Jacqueline McKee, Mark McCarron

Publikováno v: Journal of Neurology, Neurosurgery & Psychiatry. 93:A90.4-A91

IntroductionDetecting large vessel occlusion (LVO)is required to facilitate mechanical thrombectomy in stroke, but angiography is not always routinely available . Hyperdense vessel sign (HVS) and more recently conjugate eye deviation on CT brain have

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https://doi.org/10.1136/jnnp-2022-abn.295

Effects of antiplatelet therapy on stroke risk by brain imaging features of intracerebral haemorrhage and cerebral small vessel diseases: subgroup analyses of the RESTART randomised, open-label trial

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Publikováno v: BASE-Bielefeld Academic Search Engine
Al-Shahi Salman, R, Minks, D P, Mitra, D, Rodrigues, M A, Bhatnagar, P, du Plessis, J C, Joshi, Y, Dennis, M S, Murray, G D, Newby, D E, Sandercock, P A G, Sprigg, N, Stephen, J, Sudlow, C L M, Werring, D J, Whiteley, W N, Wardlaw, J M, White, P M 2019, ' Effects of antiplatelet therapy on stroke risk by brain imaging features of intracerebral haemorrhage and cerebral small vessel diseases : Subgroup analyses of the RESTART randomised, open-label trial ', Lancet Neurology, vol. 18, no. 7, pp. 643-652 . https://doi.org/10.1016/S1474-4422(19)30184-X
The Lancet Neurology, 18(7), 643. Lancet Publishing Group
RESTART collaboration & Njoku, K 2019, ' Effects of antiplatelet therapy on stroke risk by brain imaging features of intracerebral haemorrhage and cerebral small vessel diseases : subgroup analyses of the RESTART randomised, open-label trial ', The Lancet. Neurology, vol. 18, no. 7, pp. 643-652 . https://doi.org/10.1016/S1474-4422(19)30184-X

Background: Findings from the RESTART trial suggest that starting antiplatelet therapy might reduce the risk of recurrent symptomatic intracerebral haemorrhage compared with avoiding antiplatelet therapy. Brain imaging features of intracerebral haemo

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https://ora.ox.ac.uk/objects/uuid:66f71a54-b592-471a-bf9f-a98fc9be6fa5

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