Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Mark, Grossetete"'
Autor:
Elaine Edmonds, Charles Gasparovic, John C. Adair, N. Jon Shah, John Wills, Clifford Qualls, Mark Grossetete, Gary A. Rosenberg, Branko N. Huisa, Saeid Taheri, Jillian L. Prestopnik
Publikováno v:
Stroke. 42:2158-2163
Background and Purpose— Disruption of the blood–brain barrier has been proposed to be important in vascular cognitive impairment. Increased cerebrospinal fluid albumin and contrast-enhanced MRI provide supporting evidence, but quantification of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd0044cf90535f33074b263fc43581f7
https://doi.org/10.1161/strokeaha.110.611731
https://doi.org/10.1161/strokeaha.110.611731
Autor:
Mark Grossetete, Gary A. Rosenberg
Publikováno v:
Journal of Cerebral Blood Flow & Metabolism. 28:752-763
Intracerebral hemorrhage (ICH) initiates an inflammatory response with secondary growth of hemorrhage and cell death. Matrix metalloproteinase (MMP) gelatinolytic activity is increased in ICH, and synthetic inhibitors to MMPs reduce edema and hemorrh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6618c7b0789470cc6b4ab9107a5a669c
https://doi.org/10.1038/sj.jcbfm.9600572
https://doi.org/10.1038/sj.jcbfm.9600572
Autor:
Mark Grossetete, Saeid Taheri, Eduardo Candelario-Jalil, Eduardo Y. Estrada, Yi Yang, Bernd L. Fiebich, Gary A. Rosenberg, Rohit Sood
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 323:488-498
Increased permeability of the blood-brain barrier (BBB) is important in neurological disorders. Neuroinflammation is associated with increased BBB breakdown and brain injury. Tumor necrosis factor (TNF)-alpha is involved in BBB injury and edema forma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::443e62ce059cce76498e636538d71521
https://doi.org/10.1124/jpet.107.127035
https://doi.org/10.1124/jpet.107.127035
Autor:
Gary A. Rosenberg, K.M. Miller, Edward Y. Estrada, Lee Anna Cunningham, Andrew J. H. Gearing, James A. Wallace, Mark Grossetete, Susan Alexander, Abbas Razhagi
Publikováno v:
Brain Research. 893:104-112
Reperfusion damages the blood–brain barrier (BBB). Matrix metalloproteinases (MMPs) are associated with the opening of the BBB, but their cellular localization and activation mechanisms are uncertain. We used immunohistochemistry to determine the c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2847e0960fe104b79246c393f15848af
https://doi.org/10.1016/s0006-8993(00)03294-7
https://doi.org/10.1016/s0006-8993(00)03294-7
Autor:
Eduardo Candelario-Jalil, Jeffrey Thompson, Mark Grossetete, Gary A. Rosenberg, Elaine Edmonds, John C. Adair, John Wills, Saeid Taheri, Jillian L. Prestopnik
Background and Purpose— Subcortical ischemic vascular disease (SIVD) is a major form of vascular cognitive impairment (VCI) due to small vessel disease. Matrix metalloproteinases (MMPs) are neutral proteases that disrupt the blood–brain barrier a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f113e53795b032b8c62509fbbe72a83
https://europepmc.org/articles/PMC3119779/
https://europepmc.org/articles/PMC3119779/
Publikováno v:
Neurosurgery. 65(4)
OBJECTIVE: Traumatic brain injury (TBI) causes an increase in matrix metalloproteinases (MMPs), which are associated with neuroinflammation, blood-brain barrier disruption, hemorrhage, and cell death. We hypothesized that patients with TBI have an in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b0a444ed7b2006514584fe9882c393d
https://pubmed.ncbi.nlm.nih.gov/19834375
https://pubmed.ncbi.nlm.nih.gov/19834375
Autor:
Mark Grossetete, Gary A. Rosenberg
Publikováno v:
Cerebral Hemorrhage ISBN: 9783211094686
Intracerebral hemorrhage (ICH) leads to delayed cell death in the regions around the hemorrhagic mass. Apoptosis has been identified in the dying cells, but the mechanism involved is unclear. Others and us have shown that matrix metalloproteinases (M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d1f6724f994a8be35951dce025133495
https://doi.org/10.1007/978-3-211-09469-3_18
https://doi.org/10.1007/978-3-211-09469-3_18
Autor:
Mark Grossetete, Gary A. Rosenberg
Publikováno v:
Springer Protocols Handbooks ISBN: 9781603271844
Intracerebral hemorrhage (ICH) has been modeled in the laboratory with the intracerebral injection of autologous blood, injection of emboli, or proteolysis of the basal lamina surrounding cerebral capillaries by bacterial collagenase (BC). Selection
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4f91b25516ed65405330de01877893d8
https://doi.org/10.1007/978-1-60327-185-1_29
https://doi.org/10.1007/978-1-60327-185-1_29
Publikováno v:
Handbook of clinical neurology. 92
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d820b000d7c6a0bfaa98f43d1e6169d4
https://pubmed.ncbi.nlm.nih.gov/18790281
https://pubmed.ncbi.nlm.nih.gov/18790281
Publisher Summary This chapter presents the experimental models in intracerebral hemorrhage. Intracerebral hemorrhage is a major cause of death and disability in patients with stroke. The occurrence of an intracerebral hemorrhage depends on the ruptu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6f691db52ab1813d6c6d9eb18af4ff64
https://doi.org/10.1016/s0072-9752(08)01915-5
https://doi.org/10.1016/s0072-9752(08)01915-5