Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Mark, Good"'
Autor:
Tara Canonica, Emma J. Kidd, Dorota Gibbins, Eva Lana-Elola, Elizabeth M. C. Fisher, Victor L. J. Tybulewicz, Mark Good
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 18 (2024)
BackgroundTrisomy of human chromosome 21 (Hsa21) results in a constellation of features known as Down syndrome (DS), the most common genetic form of intellectual disability. Hsa21 is orthologous to three regions in the mouse genome on mouse chromosom
Externí odkaz:
https://doaj.org/article/b395bf2008984e8eba2831c22e885ced
Autor:
Mariana Neuparth-Sottomayor, Carolina C. Pina, Tatiana P. Morais, Miguel Farinha-Ferreira, Daniela Sofia Abreu, Filipa Solano, Francisco Mouro, Mark Good, Ana Maria Sebastião, Giuseppe Di Giovanni, Vincenzo Crunelli, Sandra H. Vaz
Publikováno v:
Neurobiology of Disease, Vol 186, Iss , Pp 106275- (2023)
Typical absence seizures (ASs) are brief periods of lack of consciousness, associated with 2.5–4 Hz spike-wave discharges (SWDs) in the EEG, which are highly prevalent in children and teenagers. The majority of probands in these young epileptic coh
Externí odkaz:
https://doaj.org/article/d8a29053597b48ac852afe512322526d
Autor:
Phillip M. Muza, Daniel Bush, Marta Pérez-González, Ines Zouhair, Karen Cleverley, Miriam L. Sopena, Rifdat Aoidi, Steven J. West, Mark Good, Victor L.J. Tybulewicz, Matthew C. Walker, Elizabeth M.C. Fisher, Pishan Chang
Publikováno v:
iScience, Vol 26, Iss 2, Pp 106073- (2023)
Summary: The Dp(10)2Yey mouse carries a ∼2.3-Mb intra-chromosomal duplication of mouse chromosome 10 (Mmu10) that has homology to human chromosome 21, making it an essential model for aspects of Down syndrome (DS, trisomy 21). In this study, we inv
Externí odkaz:
https://doaj.org/article/3fbb7b3045ba4d09b1a49b9bef3ec9e9
Autor:
Eva Lana-Elola, Heather Cater, Sheona Watson-Scales, Simon Greenaway, Jennifer Müller-Winkler, Dorota Gibbins, Mihaela Nemes, Amy Slender, Tertius Hough, Piia Keskivali-Bond, Cheryl L. Scudamore, Eleanor Herbert, Gareth T. Banks, Helene Mobbs, Tara Canonica, Justin Tosh, Suzanna Noy, Miriam Llorian, Patrick M. Nolan, Julian L. Griffin, Mark Good, Michelle Simon, Ann-Marie Mallon, Sara Wells, Elizabeth M. C. Fisher, Victor L. J. Tybulewicz
Publikováno v:
Disease Models & Mechanisms, Vol 14, Iss 10 (2021)
Down syndrome (DS), trisomy 21, results in many complex phenotypes including cognitive deficits, heart defects and craniofacial alterations. Phenotypes arise from an extra copy of human chromosome 21 (Hsa21) genes. However, these dosage-sensitive cau
Externí odkaz:
https://doaj.org/article/2e0de4e621364f88bbb0ae2f68e17fe9
Autor:
Pishan Chang, Daniel Bush, Stephanie Schorge, Mark Good, Tara Canonica, Nathanael Shing, Suzanna Noy, Frances K. Wiseman, Neil Burgess, Victor L.J. Tybulewicz, Matthew C. Walker, Elizabeth M.C. Fisher
Publikováno v:
Cell Reports, Vol 30, Iss 4, Pp 1152-1163.e4 (2020)
Summary: Altered neural dynamics in the medial prefrontal cortex (mPFC) and hippocampus may contribute to cognitive impairments in the complex chromosomal disorder Down syndrome (DS). Here, we demonstrate non-overlapping behavioral differences associ
Externí odkaz:
https://doaj.org/article/0726a09e79f942f28afb7ca0608d677c
Autor:
Luke D Roberts, Amanda K. Hornsby, Alanna Thomas, Martina Sassi, Aimee Kinzett, Nathan Hsiao, Bethan R David, Mark Good, Timothy Wells, Jeffrey Davies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::44e6c2b08f8b0fbca0222b205a47d274
https://doi.org/10.15252/rc.2023371152
https://doi.org/10.15252/rc.2023371152
Autor:
Phillip Muza, Daniel Bush, Marta Pérez-González, Ines Zouhair, Karen Cleverley, Miriam Llorian Sopena, Rifdat Aoidi, Steven J. West, Mark Good, Victor L.J. Tybulewicz, Matthew C. Walker, Elizabeth MC Fisher, Pishan Chang
Publikováno v:
SSRN Electronic Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5c3206ba2085dc7ed16e0d3fd2154027
https://doi.org/10.2139/ssrn.4266339
https://doi.org/10.2139/ssrn.4266339
Autor:
Mark Good
Publikováno v:
Psicológica, Vol 23, Iss 001 (2002)
The main aim of this paper is to provide an overview of current debates concerning the role of the mammalian hippocampus in learning with a particular emphasis on spatial learning. The review discusses recent debates on (1) the role of the primate
Externí odkaz:
https://doaj.org/article/2e4c1b18d9dd4a03885105bf1965dc84
Publikováno v:
Neurobiology of Learning and Memory
Successful retrieval of a memory for an entire pattern of stimulation by the presentation of a fragment of that pattern is a critical facet of memory function. We examined processes of pattern completion using novel sensory preconditioning procedures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7b806393dffd716746255283ea5200e7
https://pubmed.ncbi.nlm.nih.gov/26911788
https://pubmed.ncbi.nlm.nih.gov/26911788
Autor:
Jasper Ward-Robinson, Etienne Coutureau, Mark Good, R. C. Honey, A. S. Killcross, C. J. P. Oswald
Publikováno v:
Behavioral Neuroscience. 115:1357-1362
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d4aa20ac77c975b2c4880de733bc51f
https://doi.org/10.1037/0735-7044.115.6.1357
https://doi.org/10.1037/0735-7044.115.6.1357