Zobrazeno 1 - 10
of 256
pro vyhledávání: '"Mark, Cline"'
Autor:
Isabel R. Barnet, Shannon R. Emerzian, Ramina Behzad, Daniel J. Brooks, Trinity Tedtsen, Marcela Granados, Sun Park, Joseph Moore, John D. Olson, Lamya Karim, Mary L. Bouxsein, J. Mark Cline, Jeffrey S. Willey
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Exposure to ionizing radiation for oncological therapy increases the risk for late-onset fractures in survivors. However, the effects of total body irradiation (TBI) on adult bone are not well-characterized. The primary aim of this study was
Externí odkaz:
https://doaj.org/article/df3ebdabc72b4be6b523528734f4c0e3
Autor:
Karthik Kanagaraj, Michelle A. Phillippi, Elizabeth H. Ober, Igor Shuryak, Norman J. Kleiman, John Olson, George Schaaf, J. Mark Cline, Helen C. Turner
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract There are currently no available FDA-cleared biodosimetry tools for rapid and accurate assessment of absorbed radiation dose following a radiation/nuclear incident. Previously we developed a protein biomarker-based FAST-DOSE bioassay system
Externí odkaz:
https://doaj.org/article/54ce1567c9eb483a953a551bb96d2cf9
Autor:
Simon Deycmar, Brendan J. Johnson, Karina Ray, George W. Schaaf, Declan Patrick Ryan, Cassandra Cullin, Brandy L. Dozier, Betsy Ferguson, Benjamin N. Bimber, John D. Olson, David L. Caudell, Christopher T. Whitlow, Kiran Kumar Solingapuram Sai, Emily C. Romero, Francois J. Villinger, Armando G. Burgos, Hannah C. Ainsworth, Lance D. Miller, Gregory A. Hawkins, Jeff W. Chou, Bruno Gomes, Michael Hettich, Maurizio Ceppi, Jehad Charo, J. Mark Cline
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-21 (2024)
Abstract Background Naturally occurring colorectal cancers (CRC) in rhesus macaques share many features with their human counterparts and are useful models for cancer immunotherapy; but mechanistic data are lacking regarding the comparative molecular
Externí odkaz:
https://doaj.org/article/30efa148afbb4e31af85e684a6b0f213
Autor:
Brendan J. Johnson, Megan E. Lipford, Richard A. Barcus, John D. Olson, George W. Schaaf, Rachel N. Andrews, Jeongchul Kim, Greg O. Dugan, Simon Deycmar, Colin A. Reed, Christopher T. Whitlow, J. Mark Cline
Publikováno v:
NeuroImage, Vol 285, Iss , Pp 120491- (2024)
Cerebrovascular reactivity (CVR) is a measure of cerebral small vessels’ ability to respond to changes in metabolic demand and can be quantified using magnetic resonance imaging (MRI) coupled with a vasoactive stimulus. Reduced CVR occurs with neur
Externí odkaz:
https://doaj.org/article/5389fffff8fd477487509fbadeb757c6
Autor:
Simon Deycmar, George W Schaaf, Brendan J Johnson, J Daniel Bourland, James D Ververs, Christopher T Whitlow, J Mark Cline
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/6445b5847ba84b179d1a9a01faea0a62
Publikováno v:
Research in Diagnostic and Interventional Imaging, Vol 5, Iss , Pp 100024- (2023)
Rationale and objectives: The accurate, non-invasive, and rapid measurement of renal cortical fibrosis is needed for well-defined benchmarks of permanent injury and for use of anti-fibrotic agents. It is also needed for non-invasive and rapid assessm
Externí odkaz:
https://doaj.org/article/12bdd5f479b14bd198dfd539e58883b6
[18F]KS1, a novel ascorbate-based ligand images ROS in tumor models of rodents and nonhuman primates
Autor:
Naresh Damuka, Nagaraju Bashetti, Akiva Mintz, Avinash H. Bansode, Mack Miller, Ivan Krizan, Cristina Furdui, Bhuvanachandra Bhoopal, Krishna Kumar Gollapelli, JV Shanmukha Kumar, Gagan Deep, Greg Dugan, Mark Cline, Kiran Kumar Solingapuram Sai
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 156, Iss , Pp 113937- (2022)
Over production of reactive oxygen species (ROS) caused by altered redox regulation of signaling pathways is common in many types of cancers. While PET imaging is recognized as the standard tool for cancer imaging, there are no clinically-approved PE
Externí odkaz:
https://doaj.org/article/9037725abf044ab3a4b3c63fe778673b
Autor:
Payel Kundu, Benjamin Zimmerman, Ruby Perez, Christopher T. Whitlow, J. Mark Cline, John D. Olson, Rachel N. Andrews, Jacob Raber
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract In the brain, apolipoprotein E (apoE) plays an important role in lipid transport and response to environmental and age-related challenges, including neuronal repair following injury. While much has been learned from radiation studies in rode
Externí odkaz:
https://doaj.org/article/047a7003c4d34c38abc37c50463033df
Autor:
Fitriya N. Dewi, J. Mark Cline
Publikováno v:
Laboratory Animal Research, Vol 37, Iss 1, Pp 1-10 (2021)
Abstract Research on breast cancer pathogenesis, prevention and drug development remains an important field as this disease is still one of the leading causes of cancer death worldwide. Nonhuman primates, particularly macaque species, may serve as a
Externí odkaz:
https://doaj.org/article/fdf1b58925864eebb5d16ffed2fa79c2
Publikováno v:
PLoS ONE, Vol 17, Iss 3 (2022)
Objective To identify distinctly regulated gene markers and enriched gene sets in breast tissue of cynomolgus monkeys (Macaca fascicularis) treated for six months with either conjugated equine estrogens (CEE) or estradiol (E2) by analysis of correspo
Externí odkaz:
https://doaj.org/article/4746d8c7bd074e8ab7c94a383d5ef679