Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Mark, Bonyhadi"'
Autor:
Eric Robinet, Mélanie Couturier, Christophe Ferrand, Nicolas Montcuquet, Patricia Mercier-Letondal, Sylvain Perruche, Abdelghani Bouchekioua, Pierre Tiberghien, Anne Duperrier, Mark Bonyhadi
Publikováno v:
Immunology
Immunology, Wiley, 2008, 125 (3), pp.320-30. ⟨10.1111/j.1365-2567.2008.02843.x⟩
Immunology, Wiley, 2008, 125 (3), pp.320-30. ⟨10.1111/j.1365-2567.2008.02843.x⟩
International audience; CD3- and CD28-activated T cells expanded for 12 days ex vivo to produce suicide gene-modified T cells are hyporesponsive to alloantigens. To investigate whether this impaired alloreactivity is a result of preferential expansio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e36bf5594c259a026350d6fa8da2af9
https://doi.org/10.1111/j.1365-2567.2008.02843.x
https://doi.org/10.1111/j.1365-2567.2008.02843.x
Autor:
Lynn Csontos, Jennifer Solomon, Claudia Zylberberg, Robert J. Deans, Ian K. McNiece, Mark Bonyhadi, Rosemarie Bell, Joanne Kurtzberg, Dominic Clarke
Publikováno v:
Cytotherapy. 18(1)
Continued growth in the cell therapy industry and commercialization of cell therapies that successfully advance through clinical trials has led to increased awareness around the need for specialized and complex materials utilized in their manufacture
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcc74d3dd08ff44792c13251fa4bcb53
https://pubmed.ncbi.nlm.nih.gov/26596503
https://pubmed.ncbi.nlm.nih.gov/26596503
Publikováno v:
The Journal of Immunology. 177:1451-1459
An increasing number of studies indicate that a subset of CD4+ T cells with regulatory capacity (regulatory T cells; Tregs) can function to control organ-specific autoimmune disease. To determine whether abnormalities of thymic-derived Tregs play a r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8438fc47ab09451c7b72a83d55aed9a0
https://doi.org/10.4049/jimmunol.177.3.1451
https://doi.org/10.4049/jimmunol.177.3.1451
Autor:
Sylvie Grégoire, Sébastien Maury, David Klatzmann, Benoît L. Salomon, Muriel Sudres, José L. Cohen, Frédéric Charlotte, Mark Bonyhadi, Aurélie Trenado, Qizhi Tang
Publikováno v:
The Journal of Immunology. 176:1266-1273
CD4+CD25+ immunoregulatory T cells (Tregs) can be administered to inhibit graft-vs-host disease (GVHD) while preserving graft-vs-leukemia activity after allogeneic bone marrow transplantation in mice. Preclinical studies suggest that it is necessary
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28fbf5e16d684db0ae44035f67096321
https://doi.org/10.4049/jimmunol.176.2.1266
https://doi.org/10.4049/jimmunol.176.2.1266
Autor:
Hyam I. Levitsky, Katie Whartenby, Ivan Borrello, William Matsui, Paolo Serafini, Gladys Tan, Jahan Khalili, Rebecca Carbley, Mark Bonyhadi, Kimberly A. Noonan
Publikováno v:
Cancer Research. 65:2026-2034
A major limitation of adoptive immunotherapy is the availability of T cells specific for both terminally differentiated tumor cells and their clonogenic precursors. We show here that marrow-infiltrating lymphocytes (MILs) recognize myeloma cells afte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7024d938e93a23869e82027242a7f82
https://doi.org/10.1158/0008-5472.can-04-3337
https://doi.org/10.1158/0008-5472.can-04-3337
Autor:
S. A. Long, Ruth Taniguchi, Jane H. Buckner, Ronald J. Berenson, Mark Bonyhadi, Dale Kalamasz
Publikováno v:
Journal of Immunotherapy. 27:405-418
T-cell receptor engagement and accompanying costimulatory signals control the level of activation and functional potential of individual T cells. The authors previously developed a novel technology in which human T cells are activated and expanded in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8c82641ad34197997ea46ce6445417f
https://doi.org/10.1097/00002371-200409000-00010
https://doi.org/10.1097/00002371-200409000-00010
Autor:
Greg Szot, Jianqin Ye, Jeffrey A. Bluestone, Qizhi Tang, Mingying Bi, Kammi J. Henriksen, Mark Bonyhadi, Erik B. Finger, Hugh O. McDevitt, Emma L. Masteller
Publikováno v:
The Journal of Experimental Medicine
The low number of CD4+ CD25+ regulatory T cells (Tregs), their anergic phenotype, and diverse antigen specificity present major challenges to harnessing this potent tolerogenic population to treat autoimmunity and transplant rejection. In this study,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f0f03f182a2f8598a556386a763d87c
https://doi.org/10.1084/jem.20040139
https://doi.org/10.1084/jem.20040139
Autor:
Eric Robinet, Alexis Collette, Christophe Ferrand, Mark Bonyhadi, Anne Duperrier, Klaus Kuehlcke, Delphine Sauce, Sylvie Coito, Pierre Tiberghien, Patrick Hervé, Jean-Marie Certoux
Publikováno v:
Stem Cells and Development. 13:71-81
In a clinical trial that we recently reported, a suicide gene transfer in human primary T cells required 12 days of ex vivo culture, including activation of peripheral blood mononuclear cells (PBMC) with CD3 monoclonal antibody (CD3 mAb), retrovirus-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f303f65a93e133877cca2db66641dc0
https://doi.org/10.1089/154732804773099272
https://doi.org/10.1089/154732804773099272
Publikováno v:
The Journal of Immunology. 164:3500-3505
The cellular and humoral immune system is critically dependent upon CD40-CD154 (CD40 ligand) interactions between CD40 expressed on B cells, macrophages, and dendritic cells, and CD154 expressed primarily on CD4 T cells. Previous studies have shown t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f5832771c195845e5f0f9be43d30aaa
https://doi.org/10.4049/jimmunol.164.7.3500
https://doi.org/10.4049/jimmunol.164.7.3500
Autor:
Robert Lee, Bin Du, Andrea Wolf, Lishan Su, Jennifer Auten, Linda Rabin, Ernest F. Terwilliger, Hideto Kaneshima, Joseph M. McCune, Mark Bonyhadi, Beatrice H. Hahn
Publikováno v:
Virology. 227:45-52
Pathogenic organisms are frequently attenuated after long-term culture in vitro. The mechanisms of the attenuation process are not clear, but probably involve mutations of functions required for replication and pathogenicity in vivo. To identify thes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::279975598e13019d24490db6e9e427f3
https://doi.org/10.1006/viro.1996.8338
https://doi.org/10.1006/viro.1996.8338