Zobrazeno 1 - 10
of 78
pro vyhledávání: '"Mark, Ayers"'
Autor:
Torben Steiniche, Jeanette Baehr Georgsen, Peter Meldgaard, Anne C. Deitz, Mark Ayers, M. Catherine Pietanza, Ke Zu
Publikováno v:
Frontiers in Oncology, Vol 13 (2024)
ObjectivesPrevalence of tumor PD-L1 expression in extensive-stage small-cell lung cancer (ES-SCLC) is variable, and data on PD-L2 expression are limited. The prognostic values of these biomarkers are not well understood. The current study was conduct
Externí odkaz:
https://doaj.org/article/0e341a629a114946a42908cbc65c32ea
Autor:
David G. Pfister, Robert I. Haddad, Francis P. Worden, Jared Weiss, Ranee Mehra, Laura Q. M. Chow, Stephen V. Liu, Hyunseok Kang, Nabil F. Saba, Lori J. Wirth, Ammar Sukari, Erminia Massarelli, Mark Ayers, Andrew Albright, Andrea L. Webber, Robin Mogg, Jared Lunceford, Lingkang Huang, Razvan Cristescu, Jonathan Cheng, Tanguy Y. Seiwert, Joshua M. Bauml
Publikováno v:
Cancer Medicine, Vol 12, Iss 6, Pp 6603-6614 (2023)
Abstract Background We performed an integrated biomarker evaluation in pembrolizumab‐treated patients with R/M HNSCC enrolled in KEYNOTE‐012 or KEYNOTE‐055. The relationship between biomarkers and HPV status was explored. Methods We evaluated P
Externí odkaz:
https://doaj.org/article/41ead9902e374b769caeb779819059f4
Autor:
Marina C. Garassino, MD, Shirish Gadgeel, MD, Silvia Novello, MD, PhD, Balazs Halmos, MD, Enriqueta Felip, MD, Giovanna Speranza, MD, Rina Hui, PhD, Edward B. Garon, MD, Hidehito Horinouchi, MD, PhD, Shunichi Sugawara, MD, PhD, Delvys Rodriguez-Abreu, MD, PhD, Martin Reck, MD, Razvan Cristescu, PhD, Deepti Aurora-Garg, PhD, Andrey Loboda, PhD, Jared Lunceford, PhD, Julie Kobie, PhD, Mark Ayers, MS, Bilal Piperdi, MD, M. Catherine Pietanza, MD, Luis Paz-Ares, MD, PhD
Publikováno v:
JTO Clinical and Research Reports, Vol 4, Iss 1, Pp 100431- (2023)
Introduction: We evaluated tissue tumor mutational burden (tTMB) and mutations in STK11, KEAP1, and KRAS as biomarkers for outcomes with pembrolizumab plus platinum-based chemotherapy (pembrolizumab-combination) for NSCLC among patients in the phase
Externí odkaz:
https://doaj.org/article/5b31e33aa86a4148993ed9fca9e915ac
Autor:
Makoto Tahara, Ranee Mehra, Kei Muro, Bhumsuk Keam, Mark Ayers, Robin Mogg, Razvan Cristescu, Jared Lunceford, Andrew Albright, Jonathan Cheng, Barbara Burtness, Shilpa Gupta, Hyunseok Kang, Laura Q M Chow, Lingkang Huang, Joseph P Eder, Jared Weiss, Robert I Haddad, Tanguy Y Seiwert, Iris Gluck
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 2 (2022)
Background To characterize genomic determinants of response to pembrolizumab in recurrent/metastatic (R/M) head and neck squamous cell carcinoma (HNSCC) in the KEYNOTE-012 study.Methods Associations between biomarkers (tumor mutational burden (TMB),
Externí odkaz:
https://doaj.org/article/05117fe7797641be9fc4bdea2cd680a3
Autor:
Takashi Kojima, Sung-Bae Kim, Ken Kato, Antoine Hollebecque, Per Pfeiffer, Florian Lordick, Masahiro Tajika, Mark Ayers, Jared Lunceford, Manish Shah, Daniel Hochhauser, Peter Enzinger, Judith Raimbourg, Heung Tae Kim, A Craig Lockhart, Hendrick-Tobias Arkenau, Farid El-Hajbi, Pooja Bhagia, Z Alexander Cao, Shailaja Suryawanshi, Matt Marton
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Externí odkaz:
https://doaj.org/article/df03b38851d04671bfca314d3e6727c1
Autor:
Manish A Shah, Takashi Kojima, Daniel Hochhauser, Peter Enzinger, Judith Raimbourg, Antoine Hollebecque, Florian Lordick, Sung-Bae Kim, Masahiro Tajika, Albert Craig Lockhart, Hendrick-Tobias Arkenau, Farid El-Hajbi, Mukul Gupta, Per Pfeiffer, Pooja Bhagia, Zhu Alexander Cao, Jared Lunceford, Shailaja Suryawanshi, Mark Ayers, Matthew J Marton, Ken Kato
Publikováno v:
Future Oncology. 18:2783-2790
Aim: Investigate the relationship between response to pembrolizumab and expression of the 18-gene T cell-inflamed gene expression profile (TcellinfGEP) or PD-L1 combined positive score (CPS) in esophageal cancer. Materials & methods: This analysis in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0968c9a4709802993be2af484ebd32e
https://doi.org/10.2217/fon-2021-1134
https://doi.org/10.2217/fon-2021-1134
Autor:
Lajos Pusztai, Gabriel N. Hortobagyi, Jeffrey S. Ross, Islam Rabiul, Chang Fan, Paolo Morandi, Peter Wagner, Mark Ayers, James Stec, Kenneth R. Hess, Keith Anderson, Massimo Cristofanilli, Nuhad Ibrahim, W. Fraser Symmans, Charles M. Perou, Roman Rouzier
Supplementary Table S1 from Breast Cancer Molecular Subtypes Respond Differently to Preoperative Chemotherapy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4619efdcaeb74616e9619ccfdac75997
https://doi.org/10.1158/1078-0432.22441762.v1
https://doi.org/10.1158/1078-0432.22441762.v1
Autor:
Andrey Loboda, Jared Lunceford, Mark Ayers, Alexandra Snyder, Terrill K. McClanahan, David W. Cescon, Petros Grivas, Antoni Ribas, Michael Morrissey, Z. Alexander Cao, Hua Ma, Anran Wang, Qing Zhao, Lingkang Huang, Julie Kobie, Andrew Albright, Chunsheng Zhang, Michael Nebozhyn, Razvan Cristescu
Supplementary Figure from Transcriptomic Determinants of Response to Pembrolizumab Monotherapy across Solid Tumor Types
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1059a802b7d1f57e86f1a41f898438ff
https://doi.org/10.1158/1078-0432.22486263.v1
https://doi.org/10.1158/1078-0432.22486263.v1
Autor:
Andrey Loboda, Jared Lunceford, Mark Ayers, Alexandra Snyder, Terrill K. McClanahan, David W. Cescon, Petros Grivas, Antoni Ribas, Michael Morrissey, Z. Alexander Cao, Hua Ma, Anran Wang, Qing Zhao, Lingkang Huang, Julie Kobie, Andrew Albright, Chunsheng Zhang, Michael Nebozhyn, Razvan Cristescu
Purpose:To explore relationships between biological gene expression signatures and pembrolizumab response.Experimental Design:RNA-sequencing data on baseline tumor tissue from 1,188 patients across seven tumor types treated with pembrolizumab monothe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00587b182395db4c35151b9dce75c329
https://doi.org/10.1158/1078-0432.c.6532281.v1
https://doi.org/10.1158/1078-0432.c.6532281.v1
Autor:
Andrey Loboda, David R. Kaufman, Jonathan D. Cheng, Eric Rubin, Rodolfo Perini, Terrill K. McClanahan, Razvan Cristescu, Michael Nebozhyn, Mark Ayers
Supplementary Tables S1, S2; Supplementary Figures S1, S2, S3, S4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bcc74b79737fc4aebcc7bdefb4455f6
https://doi.org/10.1158/1078-0432.22472192.v1
https://doi.org/10.1158/1078-0432.22472192.v1