Zobrazeno 1 - 1
of 1
pro vyhledávání: '"Mark, Ator"'
Autor:
Sheila J, Miknyoczki, Susan, Jones-Bolin, Sonya, Pritchard, Kathryn, Hunter, Hugh, Zhao, Weihua, Wan, Mark, Ator, Ronald, Bihovsky, Robert, Hudkins, Sankar, Chatterjee, Andres, Klein-Szanto, Craig, Dionne, Bruce, Ruggeri
Publikováno v:
Molecular cancer therapeutics. 2(4)
Poly(ADP-ribose) polymerase 1 (PARP-1) is a nuclear zinc finger DNA-binding protein that is implicated in the repair of DNA damage. Inhibition of PARP-1 through genetic knockouts causes cells to become hypersensitive to various chemotherapeutic agent