Výsledky vyhledávání - "Marju Tilly-Kiesi"

Modulated serum activities and concentrations of paraoxonase in high density lipoprotein deficiency states

Autor: Marie-Claude Blatter Garin, Laura Calabresi, Marja-Riitta Taskinen, Marju Tilly-Kiesi, Richard W. James, Gerd Assmann, Arnold von Eckardstein, Guido Franceschini, Roberto Miccoli

Publikováno v: Atherosclerosis. 139:77-82

Paraoxonase is a high density lipoprotein (HDL) associated enzyme with a hypothesised role in the protection of low density lipoproteins (LDL) from oxidative stress. The present study examined paraoxonase in several genetically distinct HDL deficienc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e30dc55636f8e82d75e38f2d2961cf19
https://doi.org/10.1016/s0021-9150(98)00058-6

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Subjects With ApoA-I(Lys 107 →0) Exhibit Enhanced Fractional Catabolic Rate of ApoA-I in Lp(AI) and ApoA-II in Lp(AI With AII)

Autor: Gregory G. Dolnikowski, Jose M. Ordovas, Marja-Riitta Taskinen, Ernst J. Schaefer, Raija Malmström, Alice H. Lichtenstein, Marju Tilly-Kiesi

Publikováno v: Arteriosclerosis, Thrombosis, and Vascular Biology. 17:873-880

Abstract Our purpose was to examine HDL metabolism in a Finnish kindred with a 3-bp deletion in the apolipoprotein (apo) A-I gene, resulting in a deletion of Lys 107 in the mature apoA-I. Patients with this mutation [apoA-I(Lys 107 →0)] have reduce

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https://doi.org/10.1161/01.atv.17.5.873

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In vivo metabolism of apo A-I and apo A-II in subjects with apo A-I(Lys107→0) associated with reduced HDL cholesterol and Lp(AI w AII) deficiency

Autor: Christopher J. Packard, Christian Ehnholm, James Shepherd, Marju Tilly-Kiesi, Juhani Kahri, Marja-Riitta Taskinen

Publikováno v: Atherosclerosis. 128:213-222

Apolipoprotein A-I (apo A-I) and apolipoprotein A-II (apo A-II) represent 80 90% of the protein content of high density lipoproteins (HDL). Previously we have identified a Finnish family with an apo A-I variant (Lys107-->0) associated with reduced pl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::667e5993078b20b8e43f07bfd2afd7ec
https://doi.org/10.1016/s0021-9150(96)05992-8

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A compound heterozygote for hepatic lipase gene mutations Leu334–>Phe and Thr383–>Met: correlation between hepatic lipase activity and phenotypic expression

Autor: Marju Tilly-Kiesi, P. Knudsen, Juhani Kahri, Marja-Riitta Taskinen, S. Lahdenperä, Christian Ehnholm, Antikainen M, H Tenkanen, A Bensadoun, M Uusi-Oukari, Ehnholm S

Publikováno v: Europe PubMed Central
Journal of Lipid Research, Vol 37, Iss 4, Pp 825-834 (1996)

We have characterized the molecular basis for familial hepatic lipase (HL) deficiency in a Finnish family. In the propositus, the HL deficiency results from compound heterozygosity for two rare HL gene mutations, a previously unknown missense mutatio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8cb9d1ccdafd4b69f3ae690bf5d6ab2
https://doi.org/10.1016/s0022-2275(20)37580-5

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Hyperinsulinemia and insulin resistance are associated with multiple abnormalities of lipoprotein subclasses in glucose-tolerant relatives of NIDDM patients. Botnia Study Group

Autor: Marju Tilly-Kiesi, P. Knudsen, Leif Groop, Marja-Riitta Taskinen

Publikováno v: Europe PubMed Central
Journal of Lipid Research, Vol 37, Iss 7, Pp 1569-1578 (1996)

We studied the subclasses of plasma lipoproteins in normolipidemic, glucose-tolerant male relatives of noninsulin dependent diabetic patients (NIDDM), who represented either the lowest (n = 14) or the highest (n = 18) quintiles of fasting plasma insu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d450ec0673aa282b6d1c0ac6e253c3ee
https://doi.org/10.1016/s0022-2275(20)39139-2

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LDL subclasses in IDDM patients: relation to diabetic nephropathy

Autor: Giancarlo Viberti, Marja-Riitta Taskinen, Per-Henrik Groop, S. Lahdenperä, Tom Elliott, Timo Kuusi, Marju Tilly-Kiesi

Publikováno v: Diabetologia. 37:681-688

To answer the question whether the elevation of LDL-cholesterol in IDDM patients with incipient and established diabetic nephropathy is accompanied by changes in LDL size or composition, we studied distribution of LDL particles in 57 normoalbuminuric

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59206e03160cbffc1695d8c3a5109733
https://doi.org/10.1007/bf00417692

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Effects of Gemfibrozil on Low-Density Lipoprotein Particle Size, Density Distribution, and Composition in Patients With Type II Diabetes

Autor: Marja-Riitta Taskinen, Timo Kuusi, Marju Tilly-Kiesi, Helena Vuorinen-Markkola, S. Lahdenperä

Publikováno v: Diabetes Care. 16:584-592

OBJECTIVE To study the effects of gemfibrozil treatment on LDL particle size, density distribution, and composition in NIDDM patients. RESEARCH DESIGN AND METHODS We performed LDL analyses on 16 NIDDM patients with stable glycemic control. They were

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https://doi.org/10.2337/diacare.16.4.584

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The effect of lovastatin treatment on low-density lipoprotein hydrated density distribution and composition in patients with intermittent claudication and primary hypercholesterolemia

Autor: Marju Tilly-Kiesi

Publikováno v: Metabolism. 40:623-628

The effects of lovastatin treatment on density distribution and composition of low-density lipoproteins (LDL) were studied using a density gradient ultracentrifugation method in 35 hypercholesterolemic patients with severe peripheral vascular disease

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https://doi.org/10.1016/0026-0495(91)90054-z

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Lipoprotein metabolism in subjects with hepatic lipase deficiency

Autor: P. Knudsen, Marju Tilly-Kiesi, Ernst J. Schaefer, Marja-Riitta Taskinen, Gregory G. Dolnikowski, Francine K. Welty, Alice H. Lichtenstein

Publikováno v: Metabolism: clinical and experimental. 53(4)

A heritable deficiency of hepatic lipase (HL) provides insights into the physiologic function of HL in vivo. The metabolism of apolipoprotein B (apoB)-100 in very-low-density lipoprotein (VLDL), intermediate-density lipoprotein (IDL), and low-density

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b25e9d8b96ec66f524f6670dca3744c6
https://pubmed.ncbi.nlm.nih.gov/15045702

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Postprandial responses of plasma lipids and lipoproteins in subjects with apoA-I(Lys107--0)

Autor: Marju Tilly-Kiesi, J Rintarahko, Alice H. Lichtenstein, Marja-Riitta Taskinen

Publikováno v: Atherosclerosis. 137(1)

Subjects with apoA-I(Lys107--0) deletion mutation have reduced levels of plasma HDL cholesterol, apoA-I, apoA-II and Lp(AI:AII). In the present study were describe the postprandial responses of apoA-I(Lys107--0) subjects (n=6) to the ingestion of a f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd5b9876ba8ecdbcfb7d25aa4578bf67
https://pubmed.ncbi.nlm.nih.gov/9568735

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