Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Marjorie Fanjul"'
Autor:
Rémi Samain, Alexia Brunel, Thibault Douché, Marjorie Fanjul, Stéphanie Cassant-Sourdy, Julia Rochotte, Jérôme Cros, Cindy Neuzillet, Jérôme Raffenne, Camille Duluc, Aurélie Perraud, Jérémy Nigri, Véronique Gigoux, Ivan Bieche, Matteo Ponzo, Gilles Carpentier, Ilaria Cascone, Richard Tomasini, Herbert A. Schmid, Muriel Mathonnet, Rémy Nicolle, Marie-Pierre Bousquet, Yvan Martineau, Stéphane Pyronnet, Christine Jean, Corinne Bousquet
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 5, Pp 1405-1436 (2021)
Background & Aims: Cancer-associated fibroblasts (CAFs) from pancreatic adenocarcinoma (PDA) present high protein synthesis rates. CAFs express the G-protein–coupled somatostatin receptor sst1. The sst1 agonist SOM230 blocks CAF protumoral features
Externí odkaz:
https://doaj.org/article/3238e1b3879f46d6aeb288a36e8653f9
Autor:
Claudie Bosc, Nicolas Broin, Marjorie Fanjul, Estelle Saland, Thomas Farge, Charly Courdy, Aurélie Batut, Rawand Masoud, Clément Larrue, Sarah Skuli, Nicolas Espagnolle, Jean-Christophe Pagès, Alice Carrier, Frédéric Bost, Justine Bertrand-Michel, Jérôme Tamburini, Christian Récher, Sarah Bertoli, Véronique Mansat-De Mas, Stéphane Manenti, Jean-Emmanuel Sarry, Carine Joffre
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
How autophagy supports tumor cell metabolism is not fully clear. Here, the authors show that autophagy regulates lipid availability to support mitochondrial oxidative metabolism through mitochondria-endoplasmic reticulum contact sites, necessary for
Externí odkaz:
https://doaj.org/article/8cc02f2742d84833a052afbcc115d3a3
Autor:
Cindy Neuzillet, Rémy Nicolle, Jérôme Raffenne, Annemilaï Tijeras‐Raballand, Alexia Brunel, Lucile Astorgues‐Xerri, Sophie Vacher, Floriane Arbateraz, Marjorie Fanjul, Marc Hilmi, Rémi Samain, Christophe Klein, Aurélie Perraud, Vinciane Rebours, Muriel Mathonnet, Ivan Bièche, Hemant Kocher, Jérôme Cros, Corinne Bousquet
Publikováno v:
The Journal of Pathology. 258:408-425
Cancer-associated fibroblasts (CAFs) are orchestrators of the pancreatic ductal adenocarcinoma (PDAC) microenvironment. Previously we described four CAF subtypes with specific molecular and functional features. Here, we have refined our CAF subtype s
Autor:
Manon Brunet, Claire Vargas, Marjorie Fanjul, Laetitia Pieruccioni, Damien Varry, Guillaume Labrousse, Hubert Lulka, Florence Capilla, Anne Couvelard, Véronique Gigoux, Julie Guillermet-Guibert, Jérôme Torrisani, Marlène Dufresne
Background & AimsAlthough specialized and dedicated to the production of digestive enzymes, pancreatic acinar cells harbor a high plasticity and are able to modify their identity. They undergo reversible acinar-to-ductal cell metaplasia (ADM) through
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::de152fff7bfc4aaa9f6da878c1b6b7a0
https://doi.org/10.1101/2023.03.08.531649
https://doi.org/10.1101/2023.03.08.531649
Autor:
Alexia Brunel, Jérôme Raffenne, Remy Nicolle, Ilse Rooman, Elisa Espinet, Marjorie Fanjul, Aurélie Perraud, Muriel Mathonnet, Sophie Vasseur, Nelson Dusetti, Yvan Martineau, Christine Jean, Corinne Bousquet
Publikováno v:
Cancer Research. 82:C034-C034
Pancreatic ductal adenocarcinoma (PDAC) aggressiveness results from its high metastatic and chemoresistance potential. Pancreatic cancer cells are immersed in an exuberant tumor microenvironment (or stroma), which represents up to 80% of PDAC tumor v
Autor:
Ilaria Cascone, Marjorie Fanjul, Véronique Gigoux, Marie Pierre Bousquet, Christine Jean, Jerome Raffenne, Stéphane Pyronnet, Julia Rochotte, Rémy Nicolle, Matteo Ponzo, Herbert A. Schmid, Cindy Neuzillet, Yvan Martineau, Richard Tomasini, Thibault Douché, Stéphanie Cassant-Sourdy, Jérôme Cros, Jérémy Nigri, Camille Duluc, Alexia Brunel, Corinne Bousquet, Aurélie Perraud, Ivan Bièche, Muriel Mathonnet, Gilles Carpentier, Rémi Samain
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Philadelphia, PA : American Gastroenterological Association, [2015]-, 2021, 11 (5), pp.1405-1436. ⟨10.1016/j.jcmgh.2021.01.008⟩
Cellular and Molecular Gastroenterology and Hepatology, 2021, 11 (5), pp.1405-1436. ⟨10.1016/j.jcmgh.2021.01.008⟩
Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 5, Pp 1405-1436 (2021)
Cellular and Molecular Gastroenterology and Hepatology, Philadelphia, PA : American Gastroenterological Association, [2015]-, 2021, 11 (5), pp.1405-1436. ⟨10.1016/j.jcmgh.2021.01.008⟩
Cellular and Molecular Gastroenterology and Hepatology, 2021, 11 (5), pp.1405-1436. ⟨10.1016/j.jcmgh.2021.01.008⟩
Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 5, Pp 1405-1436 (2021)
Background & Aims Cancer-associated fibroblasts (CAFs) from pancreatic adenocarcinoma (PDA) present high protein synthesis rates. CAFs express the G-protein–coupled somatostatin receptor sst1. The sst1 agonist SOM230 blocks CAF protumoral features
Autor:
Marie-Bernadette Delisle, A. Billon-Galés, Christiane Susini, S. Laval, S. Le Guellec, Mélanie Pucelle, Corinne Bousquet, Stéphane Pyronnet, Arnoud Sonnenberg, Hanane Laklai, Henrik Laurell, Marjorie Fanjul
Publikováno v:
Oncogene. 33:1934-1944
Given the failure of chemo- and biotherapies to fight advanced pancreatic cancer, one major challenge is to identify critical events that initiate invasion. One priming step in epithelia carcinogenesis is the disruption of epithelial cell anchorage t
Autor:
Marjorie Fanjul, Ginette Ratovo, Marlène Dufresne, Coralie Sengenès, Bruno Lefebvre, Etienne Hollande, Julie Kerr-Conte, Valery Gmyr
Publikováno v:
Journal of Histochemistry & Cytochemistry. 58:807-823
It has been shown that adult pancreatic ductal cells can dedifferentiate and act as pancreatic progenitors. Dedifferentiation of epithelial cells is often associated with the epithelial–mesenchymal transition (EMT). In this study, we investigated t
Autor:
Marie Bernadette Delisle, Stéphanie Cassant-Sourdy, Takeshi Shimaoka, Marlène Dufresne, Marjorie Fanjul, Florence Breibach, Stéphane Pyronnet, Mary Poupot, Mounira Chalabi-Dchar, Corinne Bousquet, Camille Duluc, Muriel Mathonnet, Hubert Lulka, Rémi Samain, Catherine Roche, Shin Yonehara
Publikováno v:
Gastroenterology
Gastroenterology, WB Saunders, 2015, 148 (7), pp.1452-1465. ⟨10.1053/j.gastro.2015.02.009⟩
Gastroenterology, 2015, 148 (7), pp.1452-1465. ⟨10.1053/j.gastro.2015.02.009⟩
Gastroenterology, WB Saunders, 2015, 148 (7), pp.1452-1465. ⟨10.1053/j.gastro.2015.02.009⟩
Gastroenterology, 2015, 148 (7), pp.1452-1465. ⟨10.1053/j.gastro.2015.02.009⟩
Comment inSomatostatin receptor subtype 2 as pancreatic tumorigenesis suppressor: identification of a new targetable signaling node. [Gastroenterology. 2015]; International audience; BACKGROUND & AIMS:The KRAS gene is mutated in most pancreatic ducta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d666786966c92c5ab6cba71041df290
https://www.hal.inserm.fr/inserm-02472216
https://www.hal.inserm.fr/inserm-02472216
Autor:
Corinne Bousquet, Lucien Pradayrol, Bernard Monsarrat, Elodie Archer-Lahlou, Christiane Susini, Daniel Fourmy, Marjorie Fanjul, Jean-Pierre Estève, Carole Pichereaux, Julie Guillermet-Guibert, Frédéric Lopez, Nathalie Saint-Laurent, Audrey Ferrand
Publikováno v:
The EMBO Journal. 25:3943-3954
Phosphatidylinositol 3-kinase (PI3K) regulates many cellular functions including growth and survival, and its excessive activation is a hallmark of cancer. Somatostatin, acting through its G protein-coupled receptor (GPCR) sst2, has potent proapoptot