Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Marjon Navis"'
Autor:
Marjon Navis, Karen Tran, Shridhar Bale, Ganesh E Phad, Javier Guenaga, Richard Wilson, Martina Soldemo, Krisha McKee, Christopher Sundling, John Mascola, Yuxing Li, Richard T Wyatt, Gunilla B Karlsson Hedestam
Publikováno v:
PLoS Pathogens, Vol 10, Iss 8, p e1004337 (2014)
Broadly neutralizing antibodies (bNAbs) isolated from chronically HIV-1 infected individuals reveal important information regarding how antibodies target conserved determinants of the envelope glycoprotein (Env) spike such as the primary receptor CD4
Externí odkaz:
https://doaj.org/article/289e6f4825134e2bbb14054f8c6cd1b0
Autor:
Esther F Gijsbers, K Anton Feenstra, Ad C van Nuenen, Marjon Navis, Jaap Heringa, Hanneke Schuitemaker, Neeltje A Kootstra
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e81235 (2013)
Expression of HLA-B*57 and the closely related HLA-B*58:01 are associated with prolonged survival after HIV-1 infection. However, large differences in disease course are observed among HLA-B*57/58:01 patients. Escape mutations in CTL epitopes restric
Externí odkaz:
https://doaj.org/article/24e83fc70f6347449d9f29e4b1e3d046
Autor:
Marjon Navis, Diana Edo Matas, Andrea Rachinger, Fransje A Koning, Peter van Swieten, Neeltje A Kootstra, Hanneke Schuitemaker
Publikováno v:
PLoS ONE, Vol 3, Iss 6, p e2422 (2008)
BACKGROUND: To address evolution of HIV-1 after transmission, we studied sequence dynamics in and outside predicted epitopes of cytotoxic T lymphocytes (CTL) in subtype B HIV-1 variants that were isolated from 5 therapy-naive horizontal HLA-disparate
Externí odkaz:
https://doaj.org/article/26f4b54125da42c4b1dffb2f159e79a0
Autor:
Sang Hoon Ahn, Peter Revill, Narelle A Skinner, T. Ngyuen, Kumar Visvanathan, Marit Kramski, Stephen J. Kent, Stephen Locarnini, Marjon Navis, Danni Colledge, Julianne Bayliss, R. De Rose, Wendy R. Winnall, Alexander J. Thompson, G. Bernardi, Jacinta A Holmes, Sinthujan Jegaskanda, V. Sozzi
Publikováno v:
Journal of Virology. 88:10412-10420
The mechanisms by which hepatitis B virus (HBV) establishes and maintains chronic hepatitis B infection (CHB) are poorly defined. Innate immune responses play an important role in reducing HBV replication and pathogenesis. HBV has developed numerous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53aa9306c8b4438b3b18a042e6761d8c
https://doi.org/10.1128/jvi.00111-14
https://doi.org/10.1128/jvi.00111-14
Autor:
Gamze Isitman, Marjon Navis, Ivan Stratov, Vijaya Madhavi, Robert De Rose, Stephen J. Kent, Amy W. Chung, Leia Wren
Publikováno v:
Human Vaccines & Immunotherapeutics. 9:1011-1018
HIV-specific ADCC antibodies could play a role in providing protective immunity. We have developed a whole blood ADCC assay that measures NK cell activation in response to HIV peptide epitopes. These HIV peptide-specific ADCC responses are associated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79faa67e82f38073b45315ced04e1813
https://doi.org/10.4161/hv.23446
https://doi.org/10.4161/hv.23446
Autor:
Christopher Sundling, Marjon Navis, Ganesh E. Phad, Gunilla B. Karlsson Hedestam, Iyadh Douagi
Publikováno v:
Journal of Immunological Methods. 386:85-93
Studies in nonhuman primates offer information of high relevance to clinical medicine due to their close genetic relationship with humans. Here, we established an optimized protocol for the isolation of antibody V(D)J sequences from rhesus macaque B
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79ad4633299d41f845673b45d55cdb94
https://doi.org/10.1016/j.jim.2012.09.003
https://doi.org/10.1016/j.jim.2012.09.003
Autor:
Gregor F Lichtfuss, Marit Kramski, Gamze Isitman, Grant Rawlin, Damian F. J. Purcell, Anthony Jaworowski, Stephen J. Kent, Marjon Navis, Leia Wren
Publikováno v:
European Journal of Immunology. 42:2771-2781
Antibodies with antibody-dependent cellular cytotoxicity (ADCC) activity play an important role in protection against HIV-1 infection, but generating sufficient amounts of antibodies to study their protective efficacy is difficult. HIV-specific IgG c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4c890f1f42c8974129307d89f592dedb
https://doi.org/10.1002/eji.201242469
https://doi.org/10.1002/eji.201242469
Autor:
Nicole F. Bernard, Ivan Stratov, Matthew S. Parsons, Leia Wren, Stephen J. Kent, Gamze Isitman, Marjon Navis
Publikováno v:
Journal of Virology. 86:4488-4495
Combinations of KIR3DL1 and HLA-Bw4 alleles protect against HIV infection and/or disease progression. These combinations enhance NK cell responsiveness through the ontological process of education. However, educated KIR3DL1 + NK cells do not have enh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bec2d165a48c11c95d44369b56ebba20
https://doi.org/10.1128/jvi.06112-11
https://doi.org/10.1128/jvi.06112-11
Autor:
Amy W. Chung, Gamze Isitman, Marjon Navis, Marit Kramski, Rob J. Center, Stephen J. Kent, Ivan Stratov
Publikováno v:
Proceedings of the National Academy of Sciences. 108:7505-7510
Effective immunity to HIV is poorly understood. In particular, a role for antibody-dependent cellular cytotoxicity (ADCC) in controlling HIV is controversial. We hypothesized that significant pressure from HIV-specific ADCC would result in immune-esc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41037669c90c6229fb9cd7105b27fccb
https://doi.org/10.1073/pnas.1016048108
https://doi.org/10.1073/pnas.1016048108
Autor:
Marit J. van Gils, Emma J. Bowles, Brigitte Boeser-Nunnink, Diana Edo-Matas, Hanneke Schuitemaker, Marjon Navis, Guillaume Stewart-Jones, Angélique B. van 't Wout, Neeltje A. Kootstra, Andrea Rachinger
Publikováno v:
Virology, 405(2), 492-504. Academic Press Inc.
Virology
Virology; Vol 405
Virology
Virology; Vol 405
The HIV-1 quasispecies in peripheral blood mononuclear cells (PBMC) is considered to be a mix of actively replicating, latent, and archived viruses and may be genetically distinct from HIV-1 variants in plasma that are considered to be recently produ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c4af8b6e84ce68701868d6114485d93