Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Marjon Buscop-van Kempen"'
Autor:
Cathy van Horik, Marius J.P. Zuidweg, Anne Boerema-de Munck, Marjon Buscop-van Kempen, Erwin Brosens, Alexander L. Vahrmeijer, Jan H. von der Thüsen, René M.H. Wijnen, Robbert J. Rottier, Willemieke S.F.J. Tummers, J. Marco Schnater
Publikováno v:
European Respiratory Review, Vol 32, Iss 170 (2023)
Currently there is a global lack of consensus about the best treatment for asymptomatic congenital pulmonary airway malformation (CPAM) patients. The somatic KRAS mutations commonly found in adult lung cancer combined with mucinous proliferations are
Externí odkaz:
https://doaj.org/article/e1949ce25ea74ee49bd6a9922350095f
Autor:
Kim A. A. Schilders, Gabriëla G. Edel, Evelien Eenjes, Bianca Oresta, Judith Birkhoff, Anne Boerema-de Munck, Marjon Buscop-van Kempen, Panagiotis Liakopoulos, Petros Kolovos, Jeroen A. A. Demmers, Raymond Poot, Rene M. H. Wijnen, Dick Tibboel, Robbert J. Rottier
Publikováno v:
Frontiers in Pediatrics, Vol 10 (2022)
Congenital diaphragmatic hernia is a structural birth defect of the diaphragm, with lung hypoplasia and persistent pulmonary hypertension. Aside from vascular defects, the lungs show a disturbed balance of differentiated airway epithelial cells. The
Externí odkaz:
https://doaj.org/article/2f12adbac68b45d1bf82ee1fe83b5a3e
Autor:
Evelien Eenjes, Marjon Buscop-van Kempen, Anne Boerema-de Munck, Gabriela G Edel, Floor Benthem, Lisette de Kreij-de Bruin, Marco Schnater, Dick Tibboel, Jennifer Collins, Robbert J Rottier
Publikováno v:
eLife, Vol 10 (2021)
SOX2 expression levels are crucial for the balance between maintenance and differentiation of airway progenitor cells during development and regeneration. Here, we describe patterning of the mouse proximal airway epithelium by SOX21, which coincides
Externí odkaz:
https://doaj.org/article/fc32768b035848cc8eaaeb856def508e
Autor:
Erwin Brosens, Janine F Felix, Anne Boerema-de Munck, Elisabeth M de Jong, Elisabeth M Lodder, Sigrid Swagemakers, Marjon Buscop-van Kempen, Ronald R de Krijger, Rene M H Wijnen, Wilfred F J van IJcken, Peter van der Spek, Annelies de Klein, Dick Tibboel, Robbert J Rottier
Publikováno v:
PLoS ONE, Vol 15, Iss 11, p e0242167 (2020)
Esophageal atresia (EA) and tracheoesophageal fistula (TEF) are relatively frequently occurring foregut malformations. EA/TEF is thought to have a strong genetic component. Not much is known regarding the biological processes disturbed or which cell
Externí odkaz:
https://doaj.org/article/86775dfab8754da684eea651fe11660b
Autor:
Yadi Huang, Anne Boerema-de Munck, Marjon Buscop-van Kempen, Ilona Sluiter, Ronald de Krijger, Dick Tibboel, Robbert J. Rottier
Publikováno v:
Pulmonary Circulation, Vol 8 (2018)
We show that hypoxia inducible factor 2α (HIF2α) is highly expressed in patients with pulmonary hypertension (PH). HIF2α is expressed in every patient with congenital diaphragmatic hernia, while only half of the controls express HIF2α. Our data s
Externí odkaz:
https://doaj.org/article/5a84172441a3426ba0403e67e26bfa64
Autor:
Joshua Kapere Ochieng, Kim Schilders, Heleen Kool, Marjon Buscop-van Kempen, Anne Boerema-De Munck, Frank Grosveld, Rene Wijnen, Dick Tibboel, Robbert J Rottier
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e107248 (2014)
The adult lung contains several distinct stem cells, although their properties and full potential are still being sorted out. We previously showed that ectopic Sox2 expression in the developing lung manipulated the fate of differentiating cells. Here
Externí odkaz:
https://doaj.org/article/ccfaa64f0a8742a4aabc96192e47f490
Autor:
Yadi Huang, Joshua Kapere Ochieng, Marjon Buscop-van Kempen, Anne Boerema-de Munck, Sigrid Swagemakers, Wilfred van Ijcken, Frank Grosveld, Dick Tibboel, Robbert J Rottier
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e57695 (2013)
Lung development occurs under relative hypoxia and the most important oxygen-sensitive response pathway is driven by Hypoxia Inducible Factors (HIF). HIFs are heterodimeric transcription factors of an oxygen-sensitive subunit, HIFα, and a constituti
Externí odkaz:
https://doaj.org/article/397e9de8d6e94fe9b34cf36eb17a1f6f
Autor:
Evelien Eenjes, Floor Benthem, Anne Boerema-de Munck, Marjon Buscop-van Kempen, Dick Tibboel, Robbert J. Rottier
Publikováno v:
Cellular and Molecular Life Sciences, 80(3):79. Birkhäuser
Pulmonary neuroendocrine (NE) cells represent a small population in the airway epithelium, but despite this, hyperplasia of NE cells is associated with several lung diseases, such as congenital diaphragmatic hernia and bronchopulmonary dysplasia. The
Autor:
Ana L Pereira, Luísa T. Ferreira, Tiago Ferreira da Silva, Martine Jaegle, Marjon Buscop-van Kempen, Anne Boerema-de Munck, Wilfred van IJcken, Pedro Brites, Robbert J. Rottier, Niels Galjart, Helder Maiato
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ec6e8c61123d76d3084ec7b28802787f
https://doi.org/10.15252/rc.2022136631
https://doi.org/10.15252/rc.2022136631
Autor:
Ana L. Pereira, Tiago F. da Silva, Luísa T. Ferreira, Martine Jaegle, Marjon Buscop-van Kempen, Robbert Rottier, Wilfred F. J. van Ijcken, Pedro Brites, Niels Galjart, Helder Maiato
The first breath of air at birth marks the beginning of extrauterine life, and breathing problems due to incomplete lung development or acute respiratory distress are common in premature babies and respiratory diseases. However, the underlying molecu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c7fdb883922d35ed54906274c8d89e99
https://doi.org/10.1101/2022.04.27.489792
https://doi.org/10.1101/2022.04.27.489792