Splicing factors control triple-negative breast cancer cell mitosis through SUN2 interaction and sororin intron retention

Autor: Esmee Koedoot, Eline van Steijn, Marjolein Vermeer, Román González-Prieto, Alfred C. O. Vertegaal, John W. M. Martens, Sylvia E. Le Dévédec, Bob van de Water

Publikováno v: Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-17 (2021)

Abstract Background Triple negative breast cancer (TNBC) is an aggressive subtype of breast cancer with limited therapeutic opportunities. Recently, splicing factors have gained attention as potential targets for cancer treatment. Here we systematica

Externí odkaz: https://doaj.org/article/965c99b87fb3412fb4c7057176e1ddb5

Splicing factors control triple-negative breast cancer cell mitosis through SUN2 interaction and sororin intron retention

Autor: Eline van Steijn, Esmee Koedoot, Marjolein Vermeer, Alfred C.O. Vertegaal, Román González-Prieto, John W.M. Martens, Bob van de Water, Sylvia E. Le Dévédec

Publikováno v: Journal of Experimental & Clinical Cancer Research, 40. Springer Science and Business Media LLC
Journal of Experimental and Clinical Cancer Research, 40(1). BMC
Journal of Experimental & Clinical Cancer Research, 40(1):82. BioMed Central Ltd.
Journal of Experimental & Clinical Cancer Research : CR
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-17 (2021)

Background Triple negative breast cancer (TNBC) is an aggressive subtype of breast cancer with limited therapeutic opportunities. Recently, splicing factors have gained attention as potential targets for cancer treatment. Here we systematically evalu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::738ae893f8d5ab122e39b6a7d3e78fa3
http://hdl.handle.net/1887/3204454

3D human microvessel-on-a-chip model for studying monocyte-to-endothelium adhesion under flow - application in systems toxicology

Autor: Henriëtte L. Lanz, Angelique van den Heuvel, Remi Dulize, Thomas Olivier, Carine Poussin, Marjolein Vermeer, Bart Kramer, Manuel C. Peitsch, Karine Baumer, Emmanuel Guedj, Alexandra Laurent, Nikolai V. Ivanov, Jos Joore, Dariusz Peric, Julia Hoeng

Publikováno v: ALTEX. 37(1)

Lifestyle and genetic factors can lead to the development of atherosclerosis and, ultimately, cardiovascular adverse events. Rodent models are commonly used to investigate mechanism(s) of atherogenesis. However, the 3Rs principles, aiming to limit an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef0b48a4df635767e340a8d81d98c58b
https://pubmed.ncbi.nlm.nih.gov/31445503