Zobrazeno 1 - 10
of 99
pro vyhledávání: '"Marjolein Sluijter"'
Autor:
Jim Middelburg, Marjolein Sluijter, Gaby Schaap, Büşra Göynük, Katy Lloyd, Vitalijs Ovcinnikovs, Gijs G. Zom, Renoud J. Marijnissen, Christianne Groeneveldt, Lisa Griffioen, Gerwin G. W. Sandker, Sandra Heskamp, Sjoerd H. van der Burg, Tsolere Arakelian, Ferry Ossendorp, Ramon Arens, Janine Schuurman, Kristel Kemper, Thorbald van Hall
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract CD3 bispecific antibody (CD3 bsAb) therapy is clinically approved for refractory hematological malignancies, but responses in solid tumors have been limited so far. One of the main hurdles in solid tumors is the lack of sufficient T-cell inf
Externí odkaz:
https://doaj.org/article/36795cab2cda485e96053669065dc63a
Autor:
Jim Middelburg, Soroush Ghaffari, Tom A.W. Schoufour, Marjolein Sluijter, Gaby Schaap, Büsra Göynük, Benedetta M. Sala, Lejla Al-Tamimi, Ferenc Scheeren, Kees L.M.C. Franken, Jimmy J.L.L. Akkermans, Birol Cabukusta, Simone A. Joosten, Ian Derksen, Jacques Neefjes, Sjoerd H. van der Burg, Adnane Achour, Ruud H.M. Wijdeven, Jon Weidanz, Thorbald van Hall
Publikováno v:
Cell Reports, Vol 42, Iss 12, Pp 113516- (2023)
Summary: The immune checkpoint NKG2A/CD94 is a promising target for cancer immunotherapy, and its ligand major histocompatibility complex E (MHC-E) is frequently upregulated in cancer. NKG2A/CD94-mediated inhibition of lymphocytes depends on the pres
Externí odkaz:
https://doaj.org/article/380d9d0a2508416bb76695633b6aeefe
Autor:
Yixin Luo, Maarten H. Vermeer, Frank R. de Gruijl, Willem H. Zoutman, Marjolein Sluijter, Thorbald van Hall, Cornelis P. Tensen
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
IntroductionMycosis fungoides (MF), the most common type of Cutaneous T cell Lymphoma (CTCL), is characterized by an inflamed skin intermixed with proliferating malignant mature skin-homing CD4+ T cells. Detailed genomic analyses of MF skin biopsies
Externí odkaz:
https://doaj.org/article/a9c3b8f9ce1e4ade8c292c714046e8f5
Autor:
Rob C Hoeben, Sjoerd H van der Burg, Marjolein Sluijter, Thorbald van Hall, Joke M M Den Haan, Camilla Labrie, Christianne Groeneveldt, Priscilla Kinderman, Diana J M van den Wollenberg, Nadine van Montfoort, Lisa Griffioen, Jordi J C van Stigt Thans
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 7 (2022)
Background Many solid tumors do not respond to immunotherapy due to their immunologically cold tumor microenvironment (TME). We and others found that oncolytic viruses (OVs), including reovirus type 3 Dearing, can enhance the efficacy of immunotherap
Externí odkaz:
https://doaj.org/article/3366d822d5c7405c92a4c4b02eb41013
Autor:
Koen A. Marijt, Marjolein Sluijter, Laura Blijleven, Sofie H. Tolmeijer, Ferenc A. Scheeren, Sjoerd H. van der Burg, Thorbald van Hall
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-12 (2019)
Abstract Background T-cell mediated immunotherapy brought clinical success for many cancer patients. Nonetheless, downregulation of MHC class I antigen presentation, frequently occurring in solid cancers, limits the efficacy of these therapies. Unrav
Externí odkaz:
https://doaj.org/article/85c217c823ff441f83eae360b029fc7a
Autor:
Xiaoli Wang, Sytse J Piersma, Christopher A Nelson, Ya-Nan Dai, Ted Christensen, Eric Lazear, Liping Yang, Marjolein Sluijter, Thorbald van Hall, Ted H Hansen, Wayne M Yokoyama, Daved H Fremont
Publikováno v:
eLife, Vol 7 (2018)
A recurrent theme in viral immune evasion is the sabotage of MHC-I antigen presentation, which brings virus the concomitant issue of ‘missing-self’ recognition by NK cells that use inhibitory receptors to detect surface MHC-I proteins. Here, we r
Externí odkaz:
https://doaj.org/article/c9672d426e5e45eca7a97f1415a0cf7e
Autor:
Nadine van Montfoort, Thorbald van Hall, Lukas J.A.C. Hawinkels, Peter ten Dijke, Sjoerd H. van der Burg, Rob C. Hoeben, Diana J.M. van den Wollenberg, Camilla Labrie, Lisa Griffioen, Marjolein Sluijter, Priscilla Kinderman, Jurriaan Q. van Ginkel, Christianne Groeneveldt
Figure S2. Late TGF-β blockade does not affect tumor outgrowth.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1e34507c8eea49de6eff7fa381278f9
https://doi.org/10.1158/2767-9764.22546523
https://doi.org/10.1158/2767-9764.22546523
Autor:
Nadine van Montfoort, Thorbald van Hall, Lukas J.A.C. Hawinkels, Peter ten Dijke, Sjoerd H. van der Burg, Rob C. Hoeben, Diana J.M. van den Wollenberg, Camilla Labrie, Lisa Griffioen, Marjolein Sluijter, Priscilla Kinderman, Jurriaan Q. van Ginkel, Christianne Groeneveldt
Table S1. List of antibodies used for flow cytometric analysis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fd44db7828e94edf1dd2b9393eae0bc
https://doi.org/10.1158/2767-9764.22546505.v1
https://doi.org/10.1158/2767-9764.22546505.v1
Autor:
Nadine van Montfoort, Thorbald van Hall, Lukas J.A.C. Hawinkels, Peter ten Dijke, Sjoerd H. van der Burg, Rob C. Hoeben, Diana J.M. van den Wollenberg, Camilla Labrie, Lisa Griffioen, Marjolein Sluijter, Priscilla Kinderman, Jurriaan Q. van Ginkel, Christianne Groeneveldt
The absence of T cells in the tumor microenvironment of solid tumors is a major barrier to cancer immunotherapy efficacy. Oncolytic viruses, including reovirus type 3 Dearing (Reo), can recruit CD8+ T cells to the tumor and thereby enhance the effica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26a2a061c8382221c6d3d9021f749572
https://doi.org/10.1158/2767-9764.c.6551195
https://doi.org/10.1158/2767-9764.c.6551195
Autor:
Nadine van Montfoort, Thorbald van Hall, Lukas J.A.C. Hawinkels, Peter ten Dijke, Sjoerd H. van der Burg, Rob C. Hoeben, Diana J.M. van den Wollenberg, Camilla Labrie, Lisa Griffioen, Marjolein Sluijter, Priscilla Kinderman, Jurriaan Q. van Ginkel, Christianne Groeneveldt
Supplementary Methods 1. Methods for immunohistochemistry, Western Blotting, TGF-β1 ELISA and in vitro assays.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0185c40b8312f4cf58c87ae8ffbc2b81
https://doi.org/10.1158/2767-9764.22546508.v1
https://doi.org/10.1158/2767-9764.22546508.v1