Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Marjolein J. Vliem"'
Autor:
Soichiro Yamada, Marjolein J. Vliem, Jooske L Monster, Joleen S Cheah, Martijn Gloerich, Johan de Rooij, Helen K. Matthews, Buzz Baum, Zaw Win, Lisa Donker
Publikováno v:
The Journal of cell biology, vol 220, iss 5
The Journal of Cell Biology
Journal of Cell Biology
The Journal of Cell Biology
Journal of Cell Biology
Monster, Donker, et al. demonstrate how epithelial cells can round up as they enter mitosis while still maintaining the integrity of the epithelial barrier. This requires an asymmetric composition of mitotic cell–cell junctions, which is establishe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7dda52f977a4fce151f9a2c06e69b00a
https://escholarship.org/uc/item/4xk6b3sh
https://escholarship.org/uc/item/4xk6b3sh
Publikováno v:
Small GTPases
article-version (VoR) Version of Record
article-version (VoR) Version of Record
Epac1 and Rap1 mediate cAMP-induced tightening of endothelial junctions. We have previously found that one of the mechanisms is the inhibition of Rho-mediated tension in radial stress fibers by recruiting the RhoGAP ArhGAP29 in a complex containing t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83fd53c6a097e51ac00eb566704c19b0
Autor:
Sarah H Ross, Emma Spanjaard, Anneke Post, Marjolein J Vliem, Hendy Kristyanto, Johannes L Bos, Johan de Rooij
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e50072 (2012)
We developed new image analysis tools to analyse quantitatively the extracellular-matrix-dependent cell spreading process imaged by live-cell epifluorescence microscopy. Using these tools, we investigated cell spreading induced by activation of the s
Externí odkaz:
https://doaj.org/article/3ef73f727ea84a80bc37a1e8f771963e
Publikováno v:
Molecular and Cellular Biology, 35(14), 2495. American Society for Microbiology
The small GTPase Rap1 controls the actin cytoskeleton by regulating Rho GTPase signaling. We recently established that the Rap1 effectors Radil and Rasip1, together with the Rho GTPase activating protein ArhGAP29, mediate Rap1-induced inhibition of R
Autor:
Boudewijn M.T. Burgering, Inkie J.A. Evers-van Gogh, Miranda van Triest, Paulien E. Polderman, Marieke Visscher, Tobias B. Dansen, Maaike C. W. van den Berg, Alida M. M. Smits, Holger Rehmann, Marjolein J. Vliem
Publikováno v:
Journal of Biological Chemistry, 291(3), 1200. American Society for Biochemistry and Molecular Biology Inc.
FOXO (forkhead box O) transcription factors are tumor suppressors and increase the life spans of model organisms. Cellular stress, in particular oxidative stress caused by an increase in levels of reactive oxygen species (ROS), activates FOXOs throug
Autor:
Laurent Delys, Gil Tomás, Christophe Trésallet, Brigitte Franc, Geneviève Dom, Frédérick Libert, Carine Maenhaut, Aline Hebrant, Sandrine Beeckman, Marjolein J. Vliem, Jacques Emile Dumont, Guy Andry, Wilma C G van Staveren
Publikováno v:
Experimental Cell Research. 318:444-452
cAMP pathway activation by thyrotropin (TSH) induces differentiation and gene expression in thyrocytes. We investigated which partners of the cAMP cascade regulate gene expression modulations: protein kinase A and/or the exchange proteins directly ac
Autor:
Matthijs R.H. Kooistra, Holger Rehmann, Fried J. T. Zwartkruis, Leo S. Price, Jun Zhao, Johannes L. Bos, Kees Jalink, Martijn Gloerich, Marjolein J. Vliem, Bas Ponsioen, Zhongchun Zhang, Laila Ritsma
Publikováno v:
Molecular and Cellular Biology. 30:5421-5431
Epac1 is a guanine nucleotide exchange factor for the small G protein Rap and is involved in membrane-localized processes such as integrin-mediated cell adhesion and cell-cell junction formation. Cyclic AMP (cAMP) directly activates Epac1 by release
Autor:
Judith Klumperman, Nadia Dubé, Johannes L. Bos, Marjolein J. Vliem, Willem-Jan Pannekoek, Viola Oorschot, Holger Rehmann, Matthijs R.H. Kooistra
Publikováno v:
Cellular Signalling. 20:1608-1615
The small G-protein Rap1 is a critical regulator of cell–cell contacts and is activated by the remodeling of adherens junctions. Here we identify the Rap1 guanine nucleotide exchange factor PDZ-GEF2 as an upstream activator of Rap1 required for the
Autor:
Lars A.T. Meijer, Marjolein J. Vliem, Esther Prummel, Holger Rehmann, Johannes L. Bos, Martijn Gloerich, Marije G.A. Rensen
Publikováno v:
The Journal of Cell Biology
Direct interaction between the catalytic domain of Epac1 and the nuclear pore component RanBP2 blocks Epac1 catalytic activity and downstream cAMP signaling.
Cyclic adenosine monophosphate (cAMP) is a second messenger that relays a wide range of
Cyclic adenosine monophosphate (cAMP) is a second messenger that relays a wide range of
Autor:
Willem-Jan Pannekoek, Frank Schwede, Bas Ponsioen, Hans-Gottfried Genieser, Marjolein J. Vliem, Kees Jalink, Matthijs R.H. Kooistra, Holger Rehmann, Johannes L. Bos, Jurgen Riedl
Publikováno v:
ChemBioChem. 9:2017-2017