Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Marjolein J. F. W. Janssen"'
Autor:
W Martijn ter Haar, Magda A Meester-Smoor, Karel H M van Wely, Claudia C M M Schot, Marjolein J F W Janssen, Bart Geverts, Jacqueline Bonten, Gerard C Grosveld, Adriaan B Houtsmuller, Ellen C Zwarthoff
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e46085 (2012)
The leukemia-associated fusion protein MN1-TEL combines the transcription-activating domains of MN1 with the DNA-binding domain of the transcriptional repressor TEL. Quantitative photobleaching experiments revealed that ∼20% of GFP-tagged MN1 and T
Externí odkaz:
https://doaj.org/article/d0f348eb9bb8484dbff8f98ebdb66193
Autor:
Magda A Meester-Smoor, Marjolein J F W Janssen, W Martijn ter Haar, Karel H M van Wely, Albert-Jan L H J Aarnoudse, Gertine van Oord, Gabrielle B A van Tilburg, Ellen C Zwarthoff
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e23620 (2011)
Retinoic acid receptor (RAR) signaling is important for regulating transcriptional activity of genes involved in growth, differentiation, metabolism and reproduction. Defects in RAR signaling have been implicated in cancer. TEL, a member of the ETS f
Externí odkaz:
https://doaj.org/article/901d374f685542e7955269b26b29e914
Autor:
Tim C. de Ruijter, Maureen J.B. Aarts, Tom van Wezel, Leander Van Neste, Joep P.J. de Hoon, Manon van Engeland, Jeroen Slaats, Vivianne C. G. Tjan-Heijnen, Marjolein J. F. W. Janssen, Juergen Veeck, Bart de Vries
Publikováno v:
Laboratory Investigation, 95(7), 833-842. Nature Publishing Group
Laboratory Investigation, 95(7), 833-842
Laboratory Investigation, 95(7), 833-842
Current genome-wide methods to detect DNA-methylation in healthy and diseased tissue require high-quality DNA from fresh-frozen (FF) samples. However, well-annotated clinical samples are mostly available as formalin-fixed, paraffin-embedded (FFPE) ti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68d6f3e47c4ed5160edba6413310ff75
https://doi.org/10.1038/labinvest.2015.53
https://doi.org/10.1038/labinvest.2015.53
Autor:
Wilfred F. J. van IJcken, Marjolein J. F. W. Janssen, Magda A. Meester-Smoor, Hannie Douben, Ellen C. Zwarthoff, Gerard Grosveld, Annelies de Klein
Publikováno v:
Carcinogenesis, 29(10), 2025-2034. Oxford University Press
The oncoprotein meningioma 1 (MN1) is overexpressed in several subtypes of acute myeloid leukemia (AML) and overexpression was associated with a poor response to chemotherapy. MN1 is a cofactor of retinoic acid receptor/retinoic x receptor (RAR/RXR)-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20576c90de7e09885f097a71f2a9cedc
https://doi.org/10.1093/carcin/bgn168
https://doi.org/10.1093/carcin/bgn168
Autor:
Magda A. Meester-Smoor, Ellen C. Zwarthoff, K. H. M. van Wely, A.-J. Aarnoudse, Marjolein J. F. W. Janssen, Gerard Grosveld
Publikováno v:
Oncogene. 26:5733-5740
The translocation t(12;22)(p13;q11) creates an MN1-TEL fusion gene leading to acute myeloid leukemia. MN1 is a transcription coactivator of the retinoic acid and vitamin D receptors, and TEL (ETV6) is a member of the E26-transformation-specific famil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f359561ff7b9f764f7fe60ae1fdf958
https://doi.org/10.1038/sj.onc.1210382
https://doi.org/10.1038/sj.onc.1210382
Publikováno v:
Analytical Biochemistry. 300:27-33
The buffer requirements to maintain mitochondrial intactness and membrane potential in in vitro studies were investigated, using gradient purified yeast mitochondria. It was found that the presence of phosphate is crucial for generation of a stable m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::428d1d211d44ed5472c224d675788416
https://doi.org/10.1006/abio.2001.5438
https://doi.org/10.1006/abio.2001.5438
Publikováno v:
Yeast. 16:641-650
This study compares the effect of the growth phase on the phospholipid composition and the activity of several phospholipid biosynthetic enzymes in a wild-type yeast grown in fermentable (glucose) and non-fermentable (lactate) semi-synthetic and comp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::269ad326bc4dac06db34c9b544e7734c
https://doi.org/10.1002/(sici)1097-0061(200005)16:7<641::aid-yea578>3.0.co
https://doi.org/10.1002/(sici)1097-0061(200005)16:7<641::aid-yea578>3.0.co
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids. 1484:215-224
Rat mesangial cells synthesize and secrete a secretory phospholipase A(2) upon stimulation of the cells with cytokines, like IL-1beta and TNF and with cAMP elevating agents like forskolin. This enzyme was previously characterized to belong to group I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e5b01680d7bb16591a8141053f5535d
https://doi.org/10.1016/s1388-1981(00)00021-4
https://doi.org/10.1016/s1388-1981(00)00021-4
Autor:
Jacqueline Bonten, Marjolein J. F. W. Janssen, Bart Geverts, Adriaan B. Houtsmuller, Ellen C. Zwarthoff, Gerard Grosveld, Karel H. M. van Wely, Claudia C. M. M. Schot, W. Martijn ter Haar, Magda A. Meester-Smoor
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e46085 (2012)
PLoS ONE
PLoS One (print), 7(9). Public Library of Science
PLoS ONE
PLoS One (print), 7(9). Public Library of Science
The leukemia-associated fusion protein MN1-TEL combines the transcription-activating domains of MN1 with the DNA-binding domain of the transcriptional repressor TEL. Quantitative photobleaching experiments revealed that similar to 20% of GFP-tagged M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ee784e16eda6a5f87c30f240e4dfbf5
http://europepmc.org/articles/PMC3458806?pdf=render
http://europepmc.org/articles/PMC3458806?pdf=render
Autor:
Ben de Kruijff, Frank van Voorst, Peter Mose Larsen, Anton I.P.M. de Kroon, Marjolein J. F. W. Janssen, Ginette E. J. Ploeger, Martin R. Larsen
Publikováno v:
Biochemistry. 41(18)
In search of mitochondrial proteins interacting with phosphatidylcholine (PC), a photolabeling approach was applied, in which photoactivatable probes were incorporated into isolated yeast mitochondria. Only a limited number of proteins were labeled u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75d3e549f2d91bd18240bd46af7f4f6b
https://pubmed.ncbi.nlm.nih.gov/11980474
https://pubmed.ncbi.nlm.nih.gov/11980474