Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Marjolein J, Peters"'
Autor:
Jun Liu, Elena Carnero-Montoro, Jenny van Dongen, Samantha Lent, Ivana Nedeljkovic, Symen Ligthart, Pei-Chien Tsai, Tiphaine C. Martin, Pooja R. Mandaviya, Rick Jansen, Marjolein J. Peters, Liesbeth Duijts, Vincent W. V. Jaddoe, Henning Tiemeier, Janine F. Felix, Gonneke Willemsen, Eco J. C. de Geus, Audrey Y. Chu, Daniel Levy, Shih-Jen Hwang, Jan Bressler, Rahul Gondalia, Elias L. Salfati, Christian Herder, Bertha A. Hidalgo, Toshiko Tanaka, Ann Zenobia Moore, Rozenn N. Lemaitre, Min A Jhun, Jennifer A. Smith, Nona Sotoodehnia, Stefania Bandinelli, Luigi Ferrucci, Donna K. Arnett, Harald Grallert, Themistocles L. Assimes, Lifang Hou, Andrea Baccarelli, Eric A. Whitsel, Ko Willems van Dijk, Najaf Amin, André G. Uitterlinden, Eric J. G. Sijbrands, Oscar H. Franco, Abbas Dehghan, Tim D. Spector, Josée Dupuis, Marie-France Hivert, Jerome I. Rotter, James B. Meigs, James S. Pankow, Joyce B. J. van Meurs, Aaron Isaacs, Dorret I. Boomsma, Jordana T. Bell, Ayşe Demirkan, Cornelia M. van Duijn
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Our understanding of the functional link between differential DNA methylation and type 2 diabetes and obesity remains limited. Here the authors present a blood-based EWAS of fasting glucose and insulin among 4808 non-diabetic Europeans and identify n
Externí odkaz:
https://doaj.org/article/19891659495247948d3d723f24545ddd
Autor:
Joshua C. Bis, Holger Kirsten, Wolfgang Rathmann, Albert Hofman, Shih-Jen Hwang, Stefan Weiss, Annette Peters, Oscar H. Franco, Klodian Dhana, Brenda W J H Penninx, Katharina Schramm, Christian Herder, Joseph F. Polak, Adrie Seldenrijk, Wolfgang Koenig, Markus Loeffler, Marcus Dörr, Andy B Castaneda, Petra Wolf, Frank Beutner, Christopher J. O’Donnell, Xiaoling Zhang, Jochen Seissler, Christa Meisinger, Joachim Thiery, Holger Prokisch, Rick Jansen, Joyce B. J. van Meurs, André G. Uitterlinden, Nora Franceshini, Jennifer E. Below, Georg Homuth, Paul S. de Vries, Daniel Levy, Marjolein J. Peters, Cohorts for Heart, Gerard van Grootheest, Abbas Dehghan, Markus Scholz, Ulf Schminke, Carola Marzi, Melanie Waldenberger, Knut Krohn, Claudia Giambartolomei, Lauren E. Petty, Maryam Kavousi, Henry Völzke
Publikováno v:
Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Subclinical Working Group 2022, ' Associations of carotid intima media thickness with gene expression in whole blood and genetically predicted gene expression across 48 tissues ', Human Molecular Genetics, vol. 31, no. 7, pp. 1171-1182 . https://doi.org/10.1093/hmg/ddab236, https://doi.org/10.1093/hmg/ddab236
Human Molecular Genetics, 31(7), 1171-1182. Oxford University Press
Hum Mol Genet
Human Molecular Genetics, 31(7), 1171-1182. Oxford University Press
Hum Mol Genet
Carotid intima media thickness (cIMT) is a biomarker of subclinical atherosclerosis and a predictor of future cardiovascular events. Identifying associations between gene expression levels and cIMT may provide insight to atherosclerosis etiology. Her
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61fc58ef9e80951689e00a99b96d510b
https://pure.eur.nl/en/publications/d15b4fdb-5cf3-402f-9f22-00ca24fa6759
https://pure.eur.nl/en/publications/d15b4fdb-5cf3-402f-9f22-00ca24fa6759
Autor:
Bonnie R. Joubert, Herman T. den Dekker, Janine F. Felix, Jon Bohlin, Symen Ligthart, Emma Beckett, Henning Tiemeier, Joyce B. van Meurs, Andre G. Uitterlinden, Albert Hofman, Siri E. Håberg, Sarah E. Reese, Marjolein J. Peters, Bettina Kulle Andreassen, Eric A. P. Steegers, Roy M. Nilsen, Stein E. Vollset, Øivind Midttun, Per M. Ueland, Oscar H. Franco, Abbas Dehghan, Johan C. de Jongste, Michael C. Wu, Tianyuan Wang, Shyamal D. Peddada, Vincent W. V. Jaddoe, Wenche Nystad, Liesbeth Duijts, Stephanie J. London
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-8 (2016)
Folic acid is routinely recommended for women trying to conceive to ensure proper fetal development. Here, the authors perform a large epigenomics study to examine which fetal epigenetic changes are associated with varied maternal plasma folate level
Externí odkaz:
https://doaj.org/article/e5fa74991c5c4717866da34246f9c423
Autor:
Marjolein J. Peters, Yolande F.M. Ramos, Wouter den Hollander, Dieuwke Schiphof, Albert Hofman, André G. Uitterlinden, Edwin H.G. Oei, P. Eline Slagboom, Margreet Kloppenburg, Johan L. Bloem, Sita M.A. Bierma-Zeinstra, Ingrid Meulenbelt, Joyce B.J. van Meurs
Publikováno v:
F1000Research, Vol 5 (2016)
Objective: To identify molecular biomarkers for early knee osteoarthritis (OA), we examined whether joint effusion in the knee associated with different gene expression levels in the circulation. Materials and Methods: Joint effusion grades measured
Externí odkaz:
https://doaj.org/article/9108f9bc60174d54b1bd09c095eaedf5
Autor:
Harm-Jan Westra, Danny Arends, Tõnu Esko, Marjolein J Peters, Claudia Schurmann, Katharina Schramm, Johannes Kettunen, Hanieh Yaghootkar, Benjamin P Fairfax, Anand Kumar Andiappan, Yang Li, Jingyuan Fu, Juha Karjalainen, Mathieu Platteel, Marijn Visschedijk, Rinse K Weersma, Silva Kasela, Lili Milani, Liina Tserel, Pärt Peterson, Eva Reinmaa, Albert Hofman, André G Uitterlinden, Fernando Rivadeneira, Georg Homuth, Astrid Petersmann, Roberto Lorbeer, Holger Prokisch, Thomas Meitinger, Christian Herder, Michael Roden, Harald Grallert, Samuli Ripatti, Markus Perola, Andrew R Wood, David Melzer, Luigi Ferrucci, Andrew B Singleton, Dena G Hernandez, Julian C Knight, Rossella Melchiotti, Bernett Lee, Michael Poidinger, Francesca Zolezzi, Anis Larbi, De Yun Wang, Leonard H van den Berg, Jan H Veldink, Olaf Rotzschke, Seiko Makino, Veikko Salomaa, Konstantin Strauch, Uwe Völker, Joyce B J van Meurs, Andres Metspalu, Cisca Wijmenga, Ritsert C Jansen, Lude Franke
Publikováno v:
PLoS Genetics, Vol 11, Iss 5, p e1005223 (2015)
The functional consequences of trait associated SNPs are often investigated using expression quantitative trait locus (eQTL) mapping. While trait-associated variants may operate in a cell-type specific manner, eQTL datasets for such cell-types may no
Externí odkaz:
https://doaj.org/article/326fb91a6b344710813ff767ee21efa8
Autor:
Tianxiao Huan, Tõnu Esko, Marjolein J Peters, Luke C Pilling, Katharina Schramm, Claudia Schurmann, Brian H Chen, Chunyu Liu, Roby Joehanes, Andrew D Johnson, Chen Yao, Sai-Xia Ying, Paul Courchesne, Lili Milani, Nalini Raghavachari, Richard Wang, Poching Liu, Eva Reinmaa, Abbas Dehghan, Albert Hofman, André G Uitterlinden, Dena G Hernandez, Stefania Bandinelli, Andrew Singleton, David Melzer, Andres Metspalu, Maren Carstensen, Harald Grallert, Christian Herder, Thomas Meitinger, Annette Peters, Michael Roden, Melanie Waldenberger, Marcus Dörr, Stephan B Felix, Tanja Zeller, International Consortium for Blood Pressure GWAS (ICBP), Ramachandran Vasan, Christopher J O'Donnell, Peter J Munson, Xia Yang, Holger Prokisch, Uwe Völker, Joyce B J van Meurs, Luigi Ferrucci, Daniel Levy
Publikováno v:
PLoS Genetics, Vol 11, Iss 3, p e1005035 (2015)
Genome-wide association studies (GWAS) have uncovered numerous genetic variants (SNPs) that are associated with blood pressure (BP). Genetic variants may lead to BP changes by acting on intermediate molecular phenotypes such as coded protein sequence
Externí odkaz:
https://doaj.org/article/f8560d082fc3446faee8ddcbcfa995fc
Autor:
Jennifer A. Smith, Andrea A. Baccarelli, Jordana T. Bell, James B. Meigs, James S. Pankow, Jun Liu, Ayse Demirkan, Marjolein J. Peters, Jerome I. Rotter, Elias Salfati, Bertha Hidalgo, Audrey Y. Chu, André G. Uitterlinden, Luigi Ferrucci, Pooja R. Mandaviya, Nona Sotoodehnia, Eric A. Whitsel, Liesbeth Duijts, Marie-France Hivert, Elena Carnero-Montoro, Eric J.G. Sijbrands, Ann Zenobia Moore, Janine F. Felix, Jenny van Dongen, Najaf Amin, Tim D. Spector, Oscar H. Franco, Harald Grallert, Tiphaine Martin, Ivana Nedeljkovic, Josée Dupuis, Aaron Isaacs, Themistocles L. Assimes, Pei-Chien Tsai, Cornelia M. van Duijn, Lifang Hou, Daniel Levy, Ko Willems van Dijk, Rahul Gondalia, Samantha Lent, Abbas Dehghan, Rozenn N. Lemaitre, Jan Bressler, Christian Herder, Min A. Jhun, Symen Ligthart, Dorret I. Boomsma, Gonneke Willemsen, Toshiko Tanaka, Rick Jansen, Joyce B. J. van Meurs, Shih-Jen Hwang, Vincent W. V. Jaddoe, Donna K. Arnett, Eco J. C. de Geus, Henning Tiemeier, Stefania Bandinelli
Publikováno v:
Liu, Jun; Carnero-Montoro, Elena; van Dongen, Jenny; Lent, Samantha; Nedeljkovic, Ivana; Ligthart, Symen; Tsai, Pei-Chien; Martin, Tiphaine C; Mandaviya, Pooja R; Jansen, Rick; Peters, Marjolein J; Duijts, Liesbeth; Jaddoe, Vincent W V; Tiemeier, Henning; Felix, Janine F; Willemsen, Gonneke; de Geus, Eco J C; Chu, Audrey Y; Levy, Daniel; Hwang, Shih-Jen; ... (2019). An integrative cross-omics analysis of DNA methylation sites of glucose and insulin homeostasis. Nature communications, 10(1), p. 2581. Nature Publishing Group 10.1038/s41467-019-10487-4
Nature Communications, 10(1):2581. Nature Publishing Group
Liu, J, Carnero-Montoro, E, van Dongen, J, Lent, S, Nedeljkovic, I, Ligthart, S, Tsai, P-C, Martin, T C, Mandaviya, P R, Jansen, R, Peters, M J, Duijts, L, Jaddoe, V W V, Tiemeier, H, Felix, J F, Willemsen, G, de Geus, E J C, Chu, A Y, Levy, D, Hwang, S-J, Bressler, J, Gondalia, R, Salfati, E L, Herder, C, Hidalgo, B A, Tanaka, T, Moore, A Z, Lemaitre, R N, Jhun, M A, Smith, J A, Sotoodehnia, N, Bandinelli, S, Ferrucci, L, Arnett, D K, Grallert, H, Assimes, T L, Hou, L, Baccarelli, A, Whitsel, E A, van Dijk, K W, Amin, N, Uitterlinden, A G, Sijbrands, E J G, Franco, O H, Dehghan, A, Spector, T D, Dupuis, J, Hivert, M-F, Rotter, J I, Meigs, J B, Pankow, J S, van Meurs, J B J, Isaacs, A, Boomsma, D I, Bell, J T, Demirkan, A & van Duijn, C M 2019, ' An integrative cross-omics analysis of DNA methylation sites of glucose and insulin homeostasis ', Nature Communications, vol. 10, no. 1, 2581, pp. 2581 . https://doi.org/10.1038/s41467-019-10487-4
Nature Communications, 10. NATURE PUBLISHING GROUP
Nature Communications, 10:2581. Nature Publishing Group
Liu, J, Carnero-Montoro, E, van Dongen, J, Lent, S, Nedeljkovic, I, Ligthart, S, Tsai, P C, Martin, T C, Mandaviya, P R, Jansen, R, Peters, M J, Duijts, L, Jaddoe, V W V, Tiemeier, H, Felix, J F, Willemsen, G, de Geus, E J C, Chu, A Y, Levy, D, Hwang, S J, Bressler, J, Gondalia, R, Salfati, E L, Herder, C, Hidalgo, B A, Tanaka, T, Moore, A Z, Lemaitre, R N, Jhun, M A, Smith, J A, Sotoodehnia, N, Bandinelli, S, Ferrucci, L, Arnett, D K, Grallert, H, Assimes, T L, Hou, L, Baccarelli, A, Whitsel, E A, van Dijk, K W, Amin, N, Uitterlinden, A G, Sijbrands, E J G, Franco, O H, Dehghan, A, Spector, T D, Dupuis, J, Hivert, M F, Rotter, J I, Meigs, J B, Pankow, J S, van Meurs, J B J, Isaacs, A, Boomsma, D I, Bell, J T, Demirkan, A & van Duijn, C M 2019, ' An integrative cross-omics analysis of DNA methylation sites of glucose and insulin homeostasis ', Nature Communications, vol. 10, 2581, pp. 1-11 . https://doi.org/10.1038/s41467-019-10487-4
Nature Communications, 10:2581, 1-11. Nature Publishing Group
Nat. Commun. 10:2581 (2019)
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Nature Communications
Nature Communications, 10(1):2581. Nature Publishing Group
Liu, J, Carnero-Montoro, E, van Dongen, J, Lent, S, Nedeljkovic, I, Ligthart, S, Tsai, P-C, Martin, T C, Mandaviya, P R, Jansen, R, Peters, M J, Duijts, L, Jaddoe, V W V, Tiemeier, H, Felix, J F, Willemsen, G, de Geus, E J C, Chu, A Y, Levy, D, Hwang, S-J, Bressler, J, Gondalia, R, Salfati, E L, Herder, C, Hidalgo, B A, Tanaka, T, Moore, A Z, Lemaitre, R N, Jhun, M A, Smith, J A, Sotoodehnia, N, Bandinelli, S, Ferrucci, L, Arnett, D K, Grallert, H, Assimes, T L, Hou, L, Baccarelli, A, Whitsel, E A, van Dijk, K W, Amin, N, Uitterlinden, A G, Sijbrands, E J G, Franco, O H, Dehghan, A, Spector, T D, Dupuis, J, Hivert, M-F, Rotter, J I, Meigs, J B, Pankow, J S, van Meurs, J B J, Isaacs, A, Boomsma, D I, Bell, J T, Demirkan, A & van Duijn, C M 2019, ' An integrative cross-omics analysis of DNA methylation sites of glucose and insulin homeostasis ', Nature Communications, vol. 10, no. 1, 2581, pp. 2581 . https://doi.org/10.1038/s41467-019-10487-4
Nature Communications, 10. NATURE PUBLISHING GROUP
Nature Communications, 10:2581. Nature Publishing Group
Liu, J, Carnero-Montoro, E, van Dongen, J, Lent, S, Nedeljkovic, I, Ligthart, S, Tsai, P C, Martin, T C, Mandaviya, P R, Jansen, R, Peters, M J, Duijts, L, Jaddoe, V W V, Tiemeier, H, Felix, J F, Willemsen, G, de Geus, E J C, Chu, A Y, Levy, D, Hwang, S J, Bressler, J, Gondalia, R, Salfati, E L, Herder, C, Hidalgo, B A, Tanaka, T, Moore, A Z, Lemaitre, R N, Jhun, M A, Smith, J A, Sotoodehnia, N, Bandinelli, S, Ferrucci, L, Arnett, D K, Grallert, H, Assimes, T L, Hou, L, Baccarelli, A, Whitsel, E A, van Dijk, K W, Amin, N, Uitterlinden, A G, Sijbrands, E J G, Franco, O H, Dehghan, A, Spector, T D, Dupuis, J, Hivert, M F, Rotter, J I, Meigs, J B, Pankow, J S, van Meurs, J B J, Isaacs, A, Boomsma, D I, Bell, J T, Demirkan, A & van Duijn, C M 2019, ' An integrative cross-omics analysis of DNA methylation sites of glucose and insulin homeostasis ', Nature Communications, vol. 10, 2581, pp. 1-11 . https://doi.org/10.1038/s41467-019-10487-4
Nature Communications, 10:2581, 1-11. Nature Publishing Group
Nat. Commun. 10:2581 (2019)
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Nature Communications
Despite existing reports on differential DNA methylation in type 2 diabetes (T2D) and obesity, our understanding of its functional relevance remains limited. Here we show the effect of differential methylation in the early phases of T2D pathology by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1c4c694350da37c4a64da57355aac00
Autor:
Anna Bergström, Carrie V. Breton, Marie-France Hivert, Oscar H. Franco, Roy Miodini Nilsen, Leanne K. Küpers, Kelly M. Bakulski, Mariona Pinart, Eva Corpeleijn, Erik Melén, Paul Yousefi, Symen Ligthart, Cilla Söderhäll, Monica Cheng Munthe-Kaas, Hasan Arshad, Donglei Hu, Pieter van der Vlies, Göran Pershagen, Bilal M. Quraishi, Jörg Tost, Ashok Kumar, Inger Kull, Nathanaël Lemonnier, Ahmad Vaez, Albert Hofman, Wilfried Karmaus, Sara E. Benjamin Neelon, Joyce B. J. van Meurs, Susan Ewart, Celeste Eng, Cathrine Hoyo, M. Daniele Fallin, Juha Kere, Andrea A. Baccarelli, Olena Gruzieva, Henning Tiemeier, Allan C. Just, Isabella Annesi-Maesano, Rebecca C Richmond, Andrew P. Feinberg, Gemma C Sharp, Christina A. Markunas, Carlos Ruiz, Charles Auffray, Harold Snieder, Simon Kebede Merid, Nour Baïz, Josep M. Antó, Brenda Eskenazi, Susan K. Murphy, Hongmei Zhang, Fahimeh Falahi, Christine Ladd-Acosta, Martine Vrijheid, Jin Yao, Sarah E. Reese, Marie José Saurel-Coubizolles, Karen Huen, Zdenko Herceg, Tianyuan Wang, Lisa F. Barcellos, Siri E. Håberg, Cheng-Jian Xu, Marjan Kerkhof, Nina Holland, Stephanie J. London, John W. Holloway, Barbara Heude, Hector Hernandez-Vargas, Mariona Bustamante, Marie-Aline Charles, Augusto A. Litonjua, Tom R. Gaunt, Dawn L. DeMeo, Abbas Dehghan, Zongli Xu, Bernard F. Fuemmeler, Caroline L Relton, Jordi Sunyer, Juan R. González, Jie Ren, Marjolein J. Peters, Ulrike Gehring, Sam S. Oh, Jack A. Taylor, Soesma A Jankipersadsing, Wenche Nystad, Matthew W. Gillman, Asa Bradman, Wendy L. McArdle, Vincent W. V. Jaddoe, George Davey Smith, Dirkje S. Postma, Magnus Wickman, Johanna Lepeule, Bonnie R. Joubert, Bert Brunekreef, Stefano Guerra, Liesbeth Duijts, Gerard H. Koppelman, Janine F. Felix, Esteban G. Burchard, Allen J. Wilcox, Michael C. Wu, Lucas A. Salas, Akram Ghantous
Publikováno v:
American Journal of Human Genetics, 98(4), 680-696. Cell Press
American Journal of Human Genetics, 98(4), 680. Cell Press
American Journal of Human Genetics, 98(4), 680-696. CELL PRESS
The American Journal of Human Genetics
Recercat. Dipósit de la Recerca de Catalunya
instname
American Journal of Human Genetics, 98(4), 680. Cell Press
American Journal of Human Genetics, 98(4), 680-696. CELL PRESS
The American Journal of Human Genetics
Recercat. Dipósit de la Recerca de Catalunya
instname
Epigenetic modifications, including DNA methylation, represent a potential mechanism for environmental impacts on human disease. Maternal smoking in pregnancy remains an important public health problem that impacts child health in a myriad of ways an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a15183f3d57162432590ba820f8ffac6
https://doi.org/10.1016/j.ajhg.2016.02.019
https://doi.org/10.1016/j.ajhg.2016.02.019
Autor:
Joyce B. J. van Meurs, Eric D. Kolaczyk, Roby Joehanes, Caroline S. Fox, Albert Hofman, Andrew B. Singleton, Jose C. Florez, Andrew D. Johnson, Denis Rybin, Magic Investigators, Jaeyoung Hong, Lorna W. Harries, Lisa Pham, James B. Meigs, André G. Uitterlinden, Daniel Levy, Josée Dupuis, Stefania Bandinelli, Marie-France Hivert, Luigi Ferrucci, Dena G. Hernandez, Luke C. Pilling, Marjolein J. Peters, Brian H. Chen, Peter J. Munson, Abbas Dehghan, John D. Hogan, Saixia Ying, David Melzer
Publikováno v:
Diabetes
Diabetes, 65(12), 3794-3804. American Diabetes Association Inc.
Diabetes, 65(12), 3794-3804. American Diabetes Association Inc.
Genome-wide association studies (GWAS) have successfully identified genetic loci associated with glycemic traits. However, characterizing the functional significance of these loci has proven challenging. We sought to gain insights into the regulation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f9fb5fd5b775c231e08cf5697a47a62
https://doi.org/10.2337/db16-0470
https://doi.org/10.2337/db16-0470
Autor:
Cindy G. Boer, Paul S. de Vries, Caren E. Smith, Vinod Kumar, M. Arfan Ikram, Oscar H. Franco, Joyce B. J. van Meurs, Mohsen Ghanbari, Jeroen van Rooij, Cisca Wijmenga, Yu-Chi Lee, Marjolein J. Peters, Stefan J. Erkeland, André G. Uitterlinden, Jose M. Ordovas, Abbas Dehghan
Publikováno v:
Journal of Human Genetics, 63, 431-446
Journal of Human Genetics, 63, 4, pp. 431-446
Journal of Human Genetics, 63(4), 431-446. Nature Publishing Group
Journal of human genetics, 63(4), 431-446. Nature Publishing Group
Journal of Human Genetics, 63, 4, pp. 431-446
Journal of Human Genetics, 63(4), 431-446. Nature Publishing Group
Journal of human genetics, 63(4), 431-446. Nature Publishing Group
Item does not contain fulltext Genome-wide association studies (GWAS) have identified many susceptibility loci for cardiometabolic disorders. Most of the associated variants reside in non-coding regions of the genome including long non-coding RNAs (l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3acdcbf25225dd50217923e14c5e7c63
https://europepmc.org/articles/PMC6894420/
https://europepmc.org/articles/PMC6894420/