Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Marjo-Riitta Toppinen"'
Autor:
Timo Korjamo, Jukka Mönkkönen, Paavo Honkakoski, Mika Reinisalo, Joni J. Palmgrén, Marjo-Riitta Toppinen, Sanna Niva
Publikováno v:
European Journal of Pharmaceutical Sciences. 26:266-279
Caco-2 cell line is extensively used as an in vitro model in studying small intestinal absorption but it lacks proper expression of efflux pumps and cytochrome P450 enzymes that are involved in absorption and first pass metabolism of drugs. We create
Autor:
Seppo Rönkkö, Arto Urtti, Ilpo Jääskeläinen, Aiva Plotniece, Marjo-Riitta Toppinen, Zanna Hyvönen
Publikováno v:
Journal of controlled release : official journal of the Controlled Release Society. 99(1)
Complexes of amphiphilic cationic 1,4-dihydropyridines with DNA (lipoplexes) can be used for nonviral gene delivery. In order to achieve serum-resistant transfection system, DOPE and PEG-lipid conjugates were used to modify 1,4-dihydropyridine amphip
Publikováno v:
Cancer gene therapy. 8(2)
To evaluate human prostate carcinoma cells as targets for herpes simplex virus thymidine kinase (HSV-TK)–mediated gene therapy, we tested the utility of different viral vectors on three human cell lines DU-145, LNCaP, and PC-3. Our viral vectors we