Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Marjo, Nylund"'
Autor:
Sini Laaksonen, Maija Saraste, Marjo Nylund, Rainer Hinz, Anniina Snellman, Juha Rinne, Markus Matilainen, Laura Airas
Publikováno v:
Frontiers in Neurology, Vol 15 (2024)
BackgroundMales with multiple sclerosis (MS) have a higher risk for disability progression than females, but the reasons for this are unclear.ObjectiveWe hypothesized that potential differences in TSPO-expressing microglia between female and male MS
Externí odkaz:
https://doaj.org/article/bb2c25aefce34018ae3df5e06f9c47e6
Autor:
Jussi, Lehto, Marcus, Sucksdorff, Marjo, Nylund, Roope, Raitanen, Markus, Matilainen, Laura, Airas
Publikováno v:
Journal of Neurology. 270:2329-2332
To evaluate the effects of rituximab treatment on innate immune cell activation in primary progressive multiple sclerosis (PPMS).A 48-year-old woman with PPMS was started on rituximab shortly after diagnosis. [The PPMS patient had higher PK11195 DVRs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5157a352b5cf82032a185d04bbbe2b0f
https://doi.org/10.1007/s00415-022-11539-4
https://doi.org/10.1007/s00415-022-11539-4
Autor:
Jussi Lehto, Marjo Nylund, Markus Matilainen, Marcus Sucksdorff, Anna Vuorimaa, Johan Rajander, Saara Wahlroos, Parisa Hariri, Laura Airas
Publikováno v:
European Journal of Neurology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7bbbadc1c4d29e45a42d3373644c50cd
https://doi.org/10.1111/ene.15834
https://doi.org/10.1111/ene.15834
Publikováno v:
Wednesday, April 26.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::14bce4d5682d1b40ea14206417d75b30
https://doi.org/10.1212/wnl.0000000000202981
https://doi.org/10.1212/wnl.0000000000202981
Publikováno v:
Frontiers in Neurology, Vol 9 (2018)
Understanding the mechanisms underlying progression in multiple sclerosis (MS) is one of the key elements contributing to the identification of appropriate therapeutic targets for this under-managed condition. In addition to plaque-related focal infl
Externí odkaz:
https://doaj.org/article/d15a9b29f5e14b86ac63613b86c201b4
Autor:
Eero Polvinen, Eero Rissanen, Laura Airas, Marcus Sucksdorff, Jouni Tuisku, Markus Matilainen, Marjo Nylund, Anna Vuorimaa, Johanna Rokka
Publikováno v:
Brain
Sucksdorff et al. report that increased microglial and macrophage activation, as revealed by brain TSPO-PET, predicts multiple sclerosis progression independent of relapses during 4-year follow-up. Innate immune cell activation may thus contribute to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29a53bd328f46e9f79c7017788bf36ae
https://doi.org/10.1093/brain/awaa275
https://doi.org/10.1093/brain/awaa275
Autor:
Olavi Misin, Markus Matilainen, Marjo Nylund, Eveliina Honkonen, Eero Rissanen, Marcus Sucksdorff, Laura Airas
Publikováno v:
Neurology(R) neuroimmunologyneuroinflammation. 9(4)
Background and ObjectivesOur aim was to investigate whether 18-kDa translocator protein (TSPO) radioligand binding in gray matter (GM) predicts later disability progression in multiple sclerosis (MS).MethodsIn this prospective imaging study, innate i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdbdc16c618afbbfe6a54e88a85926ce
https://pubmed.ncbi.nlm.nih.gov/35581004
https://pubmed.ncbi.nlm.nih.gov/35581004
Publikováno v:
Brain Communications
Chronic active lesions are promotors of neurodegeneration and disease progression in multiple sclerosis. They harbour a dense rim of activated innate immune cells at the lesion edge, which promotes lesion growth and thereby induces damage. Convention
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::466ab17298c912d495a5a41f75c4ec32
https://pubmed.ncbi.nlm.nih.gov/34993478
https://pubmed.ncbi.nlm.nih.gov/34993478
Publikováno v:
Multiple sclerosis and related disorders. 46
Objective : Acute transverse myelitis is a relatively rare, frequently debilitating but potentially treatable emergency. The objective of this study was to evaluate the incidence and etiology of acute transverse myelitis in two major hospital distric
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad89ae2adf26b3724891b20763430667
https://pubmed.ncbi.nlm.nih.gov/33059215
https://pubmed.ncbi.nlm.nih.gov/33059215
Autor:
Markus Matilainen, Marjo Nylund, Iina Mannonen, Marcus Sucksdorff, Eero Rissanen, Laura Airas
BackgroundThere are already numerous B-cell depleting monoclonal anti-CD20 antibodies which have been used to reduce the inflammatory burden associated with multiple sclerosis (MS). We describe here our experience of treating MS-patients with B-cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c1114fc856210d3eee945a2d78f29ff
