Zobrazeno 1 - 10 of 10 pro vyhledávání: '"Marjie Van Hoy"'
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Optimized method for murine bone marrow collection, fixation and staining for microscopic evaluation
Autor: Angela Martzall, Victor Nunez, Oded Foreman, Marjie Van Hoy, Paula Katavolos, Laurie Leong, Monika Larson
Publikováno v: Journal of Histotechnology. 39:30-34
Murine bone marrow smear examination can be requested as a supplemental parameter to assist in the identification of hematotoxic effects of a new compound or to confirm known target biology on hematopoiesis. Cellular heterogeneity and the presence of
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4c953b40b612879042133443c8f45da1
https://doi.org/10.1080/01478885.2015.1117190
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4
Comparative Physiology of Mice and Rats: Radiometric Measurement of Vascular Parameters in Rodent Tissues
Autor: Eduardo E. Mundo, Sheila Ulufatu, Marjie Van Hoy, Leslie A. Khawli, Michelle G. Schweiger, Nicholas Majidy, Hendry S. Cahaya, Daniela Bumbaca, Paul J. Fielder, C. Andrew Boswell, Saileta Prabhu
Publikováno v: Molecular Pharmaceutics. 11:1591-1598
A solid understanding of physiology is beneficial in optimizing drug delivery and in the development of clinically predictive models of drug disposition kinetics. Although an abundance of data exists in the literature, it is often confounded by the u
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d96e6824251062a6f500e2965c9e196
https://doi.org/10.1021/mp400748t
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6
A method for removing the brain and spinal cord as one unit from adult mice and rats
Autor: Heather S. Kennedy, Floresita Puth, Marjie Van Hoy, Claire E. Le Pichon
Publikováno v: Lab Animal. 40:53-57
To collect complete rodent spinal cord samples for histological analysis, researchers typically use a method that involves fixation of the carcass, followed by decapitation and removal of the vertebrae and the spinal cord. Researchers then decalcify,
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2de0c3e01fcab71f6c7d7c081ad480c3
https://doi.org/10.1038/laban0211-53
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7
Standardizing Rodent Trimming and Embedding Guidelines for Histology: Improving Efficiency in the Laboratory
Autor: Marjie Van Hoy, Monika Larson, Robin Taylor
Publikováno v: Journal of Histotechnology. 33:157-160
This poster will outline a process created in the histology laboratory to standardize trimming and embedding guidelines to maintain consistency throughout all studies. Pathologists requested that each tissue be assigned a fixed number for more-effici
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f86f8282ee26641cab73fc392cd41ee3
https://doi.org/10.1179/his.2010.33.4.157
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8
Enhanced tumor retention of a radiohalogen label for site-specific modification of antibodies
Autor: Jan Marik, Anthony Trias, C. Andrew Boswell, Nicholas Majidy, Noe A Reyes, Jagath Reddy Junutula, Marjie Van Hoy, Victor Yip, Paul J. Fielder, Eduardo E. Mundo, Sheila Ulufatu, Leslie A. Khawli, Simon Williams, Saritha N Goriparthi, Michael J Elowson, Herman Gill, Daniela Bumbaca
Publikováno v: Journal of medicinal chemistry. 56(23)
A known limitation of iodine radionuclides for labeling and biological tracking of receptor targeted proteins is the tendency of iodotyrosine to rapidly diffuse from cells following endocytosis and lysosomal degradation. In contrast, radiometal-chela
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57b901e29eb14e7f3f1856bd646da50b
https://pubmed.ncbi.nlm.nih.gov/24283797
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9
Effect of immune complex formation on the distribution of a novel antibody to the ovarian tumor antigen CA125
Autor: William Mallet, Suzanna Clark, Michelle G. Schweiger, Ben-Quan Shen, Margaret Kenrick, Cinthia V. Pastuskovas, Gregory L. Bennett, Paul J. Fielder, Marjie Van Hoy, Leslie A. Khawli, Jay Tibbitts, Siao Ping Tsai, Mohammed Majidy, Sarajane Ross
Publikováno v: Drug metabolism and disposition: the biological fate of chemicals. 38(12)
3A5 is a novel antibody that binds repeated epitopes within CA125, an ovarian tumor antigen that is shed into the circulation. Binding to shed antigen may limit the effectiveness of therapeutic antibodies because of unproductive immune complex (IC) f
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16e42877be390ebfe70ecc30556b5e66
https://pubmed.ncbi.nlm.nih.gov/20823292
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