Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Marjie Hard"'
Autor:
Jingsong Cao, Minjung Choi, Eleonora Guadagnin, Maud Soty, Marine Silva, Vincent Verzieux, Edward Weisser, Arianna Markel, Jenny Zhuo, Shi Liang, Ling Yin, Andrea Frassetto, Anne-Renee Graham, Kristine Burke, Tatiana Ketova, Cosmin Mihai, Zach Zalinger, Becca Levy, Gilles Besin, Meredith Wolfrom, Barbara Tran, Christopher Tunkey, Erik Owen, Joe Sarkis, Athanasios Dousis, Vladimir Presnyak, Christopher Pepin, Wei Zheng, Lei Ci, Marjie Hard, Edward Miracco, Lisa Rice, Vi Nguyen, Mike Zimmer, Uma Rajarajacholan, Patrick F. Finn, Gilles Mithieux, Fabienne Rajas, Paolo G. V. Martini, Paloma H. Giangrande
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Glycogen Storage Disease 1a (Gsd1a) is an inherited disorder caused by glucose 6-phosphatase (G6Pase-α) deficiency and characterized by hypoglycaemia and high risk of liver cancer. Here the authors develop a mRNA-based G6Pase-α delivery therapy tha
Externí odkaz:
https://doaj.org/article/977236f43e9f4fb4a8b6a0322537f1cb
Publikováno v:
Drugs in R&D, Vol 19, Iss 3, Pp 277-287 (2019)
Abstract Background and Objectives Samidorphan (SAM) is a novel μ-opioid receptor antagonist. We report clinical pharmacokinetic (PK) properties of SAM following different routes of administration, and the effects of food and age on the PK of SAM fo
Externí odkaz:
https://doaj.org/article/5dbc12a4dc9c44f38dc7b1e9e279a1ee
Autor:
Rajeshwari Mahalingam, Michael Oldham, Corey Puryear, Prashant Bansal, Balaji Sriram, Dharit Patel, Henry Jacotin, Marjie Hard, Million Arefayene, Bernard Ravina, Marcio Souza, Steven Petrou
Publikováno v:
Monday, April 24.
Autor:
Brian Pfister, Rajeshwari Mahalingam, Michael Oldham, Dharit Patel, Henry Jacotin, Marjie Hard, Corey Puryear, Bernard Ravina, Marcio Souza, Steven Petrou
Publikováno v:
Tuesday, April 25.
Autor:
Lei Ci, Marjie Hard, Hannah Zhang, Srujan Gandham, Serenus Hua, John Wickwire, Tod Wehrman, Richard Slauter, Andrew Auerbach, Matthew Kenney, Greg Mercer, Tracy Hendrick, Örn Almarsson, Eugene Cheung, Douglas Burdette
Publikováno v:
Drug Metabolism and Disposition. :DMD-AR
Autor:
Allison August, Husain Z. Attarwala, Sunny Himansu, Shiva Kalidindi, Sophia Lu, Rolando Pajon, Shu Han, Jean-Michel Lecerf, Joanne E. Tomassini, Marjie Hard, Leon M. Ptaszek, James E. Crowe, Tal Zaks
Publikováno v:
Nature Medicine. 28:1095-1096
Autor:
Christopher Tunkey, Minjung Choi, Wei Zheng, Gilles Besin, Lisa M. Rice, Andrea Frassetto, Athanasios Dousis, Edward J. Miracco, Uma Rajarajacholan, Erik Owen, Patrick Finn, Fabienne Rajas, Eleonora Guadagnin, Kristin E. Burke, Mike Zimmer, Vincent Verzieux, Christopher Pepin, Cosmin Mihai, meredith##Wolfrom, Maud Soty, Becca Levy, Joe Sarkis, Zach Zalinger, Barbara Tran, Marine Silva, Arianna Markel, Ling Yin, Paloma H. Giangrande, Vi Nguyen, Jingsong Cao, Marjie Hard, Paolo Martini, Gilles Mithieux, Jenny Zhuo, Shi Liang, Edward Weisser, Vladimir Presnyak, Anne-Renee##Graham, Tatiana Ketova, Lei Ci
Publikováno v:
Nature Communications
Nature Communications, Nature Publishing Group, 2021, 12 (1), pp.3090. ⟨10.1038/s41467-021-23318-2⟩
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Nature Communications, Nature Publishing Group, 2021, 12 (1), pp.3090. ⟨10.1038/s41467-021-23318-2⟩
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Glycogen Storage Disease 1a (GSD1a) is a rare, inherited metabolic disorder caused by deficiency of glucose 6-phosphatase (G6Pase-α). G6Pase-α is critical for maintaining interprandial euglycemia. GSD1a patients exhibit life-threatening hypoglycemi
Autor:
Daniel Jericó, Zinnia P. Parra-Guillen, Lei Jiang, Lin T. Guey, Antonio Fontanellas, Marjie Hard, Diego Vera-Yunca, Iñaki F. Trocóniz, Paolo Martini
Publikováno v:
Br J Pharmacol
Background and purpose Acute intermittent porphyria (AIP) results from haplo-insufficiency of the porphobilinogen deaminase (PBGD) gene encoding the third enzyme in the haem biosynthesis pathway. As liver is the main organ of pathology for AIP, emerg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28b4375f60ab51bec1687ca873bf6e94
https://europepmc.org/articles/PMC7312321/
https://europepmc.org/articles/PMC7312321/
Publikováno v:
Psychopharmacology bulletin. 47(3)
Aripiprazole lauroxil (AL) is an FDA-approved treatment for schizophrenia. AL is a non-ester prodrug of aripiprazole that results in extended systemic release of aripiprazole after intramuscular (IM) administration. This Phase-1 study evaluated the p
Autor:
Gideon Koren, Zina Levichek, Eran Kozer, Myla E. Moretti, Marjie Hard, Dorothy A. Lyszkiewicz, Yaron Yagev
Publikováno v:
Pediatric nephrology (Berlin, Germany). 18(7)
Currently, a suspension of crushed tablets of amlodidpine is widely used in children with hypertension without knowledge of its bioavailability. A comparative bioavailability study of a tablet and suspension formulation of amlodipine was completed in