Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Marjana Grandič"'
Autor:
Marjana Grandič, Robert Frangež
Publikováno v:
Marine Drugs, Vol 12, Iss 5, Pp 2408-2421 (2014)
Polymeric 3-alkylpyridinium salts (poly-APS) are among the most studied natural bioactive compounds extracted from the marine sponge, Reniera sarai. They exhibit a wide range of biological activities, and the most prominent among them are the anti-ac
Externí odkaz:
https://doaj.org/article/c1f745aa61444b81a3b05ca54863b6d3
Autor:
Sabina Berne, Maja Čemažar, Robert Frangež, Polona Juntes, Simona Kranjc, Marjana Grandič, Monika Savarin, Tom Turk
Publikováno v:
Marine Drugs, Vol 16, Iss 10, p 367 (2018)
The alkylpyridinium polymer APS8, a potent antagonist of α7 nicotinic acetylcholine receptors (nAChRs), selectively induces apoptosis in non-small cell lung cancer cells but not in normal lung fibroblasts. To explore the potential therapeutic value
Externí odkaz:
https://doaj.org/article/749e07beda914e5fb2f9f3a274d06f6f
Publikováno v:
Plant Disease. 102:1334-1340
In the present study, the genetic relationships and ergot-alkaloid production of the fungus Claviceps purpurea on grasses were investigated, to determine any associations between grass host specificity, ergot-alkaloid production, and geographic origi
Publikováno v:
Toxicological Sciences. 150:283-291
The effects of Beauvericin (BEA) produced by the fungusBeauveria bassianaandFusariumsp. on neuromuscular transmission and contractility were determined in an isolated neuromuscular mouse hemidiaphragm preparation. BEA (5 µM) significantly inhibits i
Autor:
Tom Turk, Sabina Berne, Simona Kranjc, Marjana Grandič, Maja Čemažar, Polona Juntes, Monika Savarin, Robert Frangež
Publikováno v:
Marine Drugs
Volume 16
Issue 10
Marine Drugs, Vol 16, Iss 10, p 367 (2018)
Marine drugs, vol. 16, no. 10, 367, 2018.
Volume 16
Issue 10
Marine Drugs, Vol 16, Iss 10, p 367 (2018)
Marine drugs, vol. 16, no. 10, 367, 2018.
The alkylpyridinium polymer APS8, a potent antagonist of &alpha
7 nicotinic acetylcholine receptors (nAChRs), selectively induces apoptosis in non-small cell lung cancer cells but not in normal lung fibroblasts. To explore the potential therapeu
7 nicotinic acetylcholine receptors (nAChRs), selectively induces apoptosis in non-small cell lung cancer cells but not in normal lung fibroblasts. To explore the potential therapeu
Publikováno v:
Toxicology Letters
Toxicology Letters, Elsevier, 2017, 281, pp.95-101. ⟨10.1016/j.toxlet.2017.09.007⟩
Toxicology Letters, 2017, 281, pp.95-101. ⟨10.1016/j.toxlet.2017.09.007⟩
Toxicology Letters, Elsevier, 2017, 281, pp.95-101. ⟨10.1016/j.toxlet.2017.09.007⟩
Toxicology Letters, 2017, 281, pp.95-101. ⟨10.1016/j.toxlet.2017.09.007⟩
International audience; The effects of natural polymeric alkylpyridinium salt (nPoly-3-APS), a potent acetylcholinesterase inhibitor isolated from the marine sponge Reniera sarai, were studied on isolated mouse phrenic nerve-hemidiaphragm muscle prep
Autor:
Robert Frangež, Marjana Grandič
Publikováno v:
Marine Drugs
Marine Drugs, Vol 12, Iss 5, Pp 2408-2421 (2014)
Marine Drugs, Vol 12, Iss 5, Pp 2408-2421 (2014)
Polymeric 3-alkylpyridinium salts (poly-APS) are among the most studied natural bioactive compounds extracted from the marine sponge, Reniera sarai. They exhibit a wide range of biological activities, and the most prominent among them are the anti-ac
Autor:
Blanka Premrov Bajuk, Robert Frangež, Kristina Sepčić, Marjana Grandič, Marinka Drobnič Košorok
Publikováno v:
Toxicology in Vitro. 27:627-631
APS12-2 and APS3 are synthetic analogues of polymeric alkylpyridinium salts (poly-APS) isolated from the marine sponge Reniera sarai. The aim of the present study was to determine the possible direct contractile effects of these two synthetic molecul
Autor:
Marjana Grandič, Kristina Sepčić, Tom Turk, Evelyne Benoit, Jordi Molgó, Robert Frangež, Rómulo Aráoz
Publikováno v:
Toxicology
Toxicology, Elsevier, 2013, 303C, pp.25-33. ⟨10.1016/j.tox.2012.10.013⟩
Toxicology, Elsevier, 2013, 303C, pp.25-33. ⟨10.1016/j.tox.2012.10.013⟩
International audience; The in vivo and in vitro toxic effects of the synthetic polymeric 3-alkylpyridinium salt (APS3), from the Mediterranean marine sponge Reniera sarai, were evaluated on mammals, with emphasis to determine its mode of action. The
Publikováno v:
Bioorganic & Medicinal Chemistry. 20:1659-1664
Naturally occurring 3-alkylpyridinium polymers from the marine sponge Reniera sarai are membrane-active compounds exerting a selective cytotoxicity towards non small cell lung cancer cells, and stable transfection of nucleated mammalian cells. In vie