Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Marjan Zaman"'
Autor:
Minkyu Jung, Yanping Yang, Jaclyn E. McCloskey, Marjan Zaman, Yogindra Vedvyas, Xianglan Zhang, Dessislava Stefanova, Katherine D. Gray, Irene M. Min, Raza Zarnegar, Yoon Young Choi, Jae-Ho Cheong, Sung Hoon Noh, Sun Young Rha, Hyun Cheol Chung, Moonsoo M. Jin
Publikováno v:
Molecular Therapy: Oncolytics, Vol 18, Iss , Pp 587-601 (2020)
Cancer therapy utilizing adoptive transfer of chimeric antigen receptor (CAR) T cells has demonstrated remarkable clinical outcomes in hematologic malignancies. However, CAR T cell application to solid tumors has had limited success, partly due to th
Externí odkaz:
https://doaj.org/article/2d219804286b4b9eabd7428add107045
Autor:
Irene M. Min, Moonsoo M. Jin, Thomas J. Fahey, Rasa Zarnegar, Andrew B. Tassler, Theresa Scognamiglio, Paul J. Christos, Dessislava Stefanova, Heng Liang, Timothy M. Ullmann, Marjan Zaman, Enda Shevlin, Yanping Yang, Steve El Eshaky, Olivia R. Kalloo, Yogindra Vedvyas, Jaclyn E. McCloskey, Katherine D. Gray
A model for ICAM1-CAR T and anti-PD1 antibody activities in advanced thyroid cancers.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fefdcd8131bc1ba4b4da4a1393ef4da
https://doi.org/10.1158/1078-0432.22476350
https://doi.org/10.1158/1078-0432.22476350
Data from PD1 Blockade Enhances ICAM1-Directed CAR T Therapeutic Efficacy in Advanced Thyroid Cancer
Autor:
Irene M. Min, Moonsoo M. Jin, Thomas J. Fahey, Rasa Zarnegar, Andrew B. Tassler, Theresa Scognamiglio, Paul J. Christos, Dessislava Stefanova, Heng Liang, Timothy M. Ullmann, Marjan Zaman, Enda Shevlin, Yanping Yang, Steve El Eshaky, Olivia R. Kalloo, Yogindra Vedvyas, Jaclyn E. McCloskey, Katherine D. Gray
Purpose:Advanced thyroid cancers, including poorly differentiated and anaplastic thyroid cancer (ATC), are lethal malignancies with limited treatment options. The majority of patients with ATC have responded poorly to programmed death 1 (PD1) blockad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1b892ec492b9e25c8510c7cc3249031
https://doi.org/10.1158/1078-0432.c.6529379
https://doi.org/10.1158/1078-0432.c.6529379
Autor:
Moonsoo M. Jin, Thomas J. Fahey, Rasa Zarnegar, Andrew B. Tassler, Katherine D. Gray, Suraj Panjwani, Spencer Park, Susan Park, Weibin Wang, Maureen D. Moore, Theresa Scognamiglio, Brian Wyrwas, Marjan Zaman, Yogindra Vedvyas, Enda Shevlin, Irene M. Min
Figure S1. PTCs with BRAFV600E mutations are associated with ICAM-1 Overexpression; Figure S2. Tumor tissue morphology in ATC patients.; Figure S3. ICAM-1-overexpressing ATC cell lines are more proliferative.; Figure S4. ICAM-1 CAR T cell phenotype c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61a9e310a181d4f64b0ec5200bddbe20
https://doi.org/10.1158/1078-0432.22463076.v1
https://doi.org/10.1158/1078-0432.22463076.v1
Autor:
Irene M. Min, Moonsoo M. Jin, Thomas J. Fahey, Rasa Zarnegar, Andrew B. Tassler, Theresa Scognamiglio, Paul J. Christos, Dessislava Stefanova, Heng Liang, Timothy M. Ullmann, Marjan Zaman, Enda Shevlin, Yanping Yang, Steve El Eshaky, Olivia R. Kalloo, Yogindra Vedvyas, Jaclyn E. McCloskey, Katherine D. Gray
Expression of ICAM1 and PD-L1 in anaplastic thyroid tumor cell lines.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e6c3bf8bbbb48fc754c52a07636ea89
https://doi.org/10.1158/1078-0432.22476359
https://doi.org/10.1158/1078-0432.22476359
Autor:
Irene M. Min, Moonsoo M. Jin, Thomas J. Fahey, Rasa Zarnegar, Andrew B. Tassler, Theresa Scognamiglio, Paul J. Christos, Dessislava Stefanova, Heng Liang, Timothy M. Ullmann, Marjan Zaman, Enda Shevlin, Yanping Yang, Steve El Eshaky, Olivia R. Kalloo, Yogindra Vedvyas, Jaclyn E. McCloskey, Katherine D. Gray
PD1 inhibition enhances survival benefit of CAR T treatment in KHM-5M xenografts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02c21a12ef8b3be9c3c8a123575945db
https://doi.org/10.1158/1078-0432.22476353
https://doi.org/10.1158/1078-0432.22476353
Autor:
Moonsoo M. Jin, Thomas J. Fahey, Rasa Zarnegar, Andrew B. Tassler, Katherine D. Gray, Suraj Panjwani, Spencer Park, Susan Park, Weibin Wang, Maureen D. Moore, Theresa Scognamiglio, Brian Wyrwas, Marjan Zaman, Yogindra Vedvyas, Enda Shevlin, Irene M. Min
Purpose: Poorly differentiated thyroid cancer and anaplastic thyroid cancer (ATC) are rare yet lethal malignancies with limited treatment options. Many malignant tumors, including papillary thyroid cancer (PTC) and ATC, are associated with increased
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3484f7a5c6bae0c0fda6c9d16275449e
https://doi.org/10.1158/1078-0432.c.6525303
https://doi.org/10.1158/1078-0432.c.6525303
Autor:
Jaclyn E. McCloskey, Katherine D. Gray, Moonsoo M. Jin, Marjan Zaman, Steve El Eshaky, Rasa Zarnegar, Andrew B. Tassler, Olivia R. Kalloo, Paul J. Christos, Heng Liang, Yogindra Vedvyas, Theresa Scognamiglio, Irene M. Min, Yanping Yang, Thomas J. Fahey, Dessislava Stefanova, Timothy M. Ullmann, Enda Shevlin
Publikováno v:
Clin Cancer Res
Purpose: Advanced thyroid cancers, including poorly differentiated and anaplastic thyroid cancer (ATC), are lethal malignancies with limited treatment options. The majority of patients with ATC have responded poorly to programmed death 1 (PD1) blocka
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25adccca6be2382f8ae37b8f8a8f95d3
https://doi.org/10.1158/1078-0432.ccr-20-1523
https://doi.org/10.1158/1078-0432.ccr-20-1523
Autor:
Marjan Zaman, Sun Young Rha, Xianglan Zhang, Jaclyn E. McCloskey, Irene M. Min, Jae Ho Cheong, Hyun Cheol Chung, Katherine D. Gray, Minkyu Jung, Dessislava Stefanova, Sung Hoon Noh, Yanping Yang, Moonsoo M. Jin, Raza Zarnegar, Yoon Young Choi, Yogindra Vedvyas
Publikováno v:
Molecular Therapy: Oncolytics, Vol 18, Iss, Pp 587-601 (2020)
Molecular Therapy Oncolytics
Molecular Therapy Oncolytics
Cancer therapy utilizing adoptive transfer of chimeric antigen receptor (CAR) T cells has demonstrated remarkable clinical outcomes in hematologic malignancies. However, CAR T cell application to solid tumors has had limited success, partly due to th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53698cb727812e1c8e5925047271e202
http://www.sciencedirect.com/science/article/pii/S2372770520301261
http://www.sciencedirect.com/science/article/pii/S2372770520301261
Autor:
Kelly M. Gillen, Padraic O' Malley, Ju-Young Kim, Yogindra Vedvyas, Zhe Liu, Richard K. Lee, Kofi Deh, Dina Bedretdinova, Yi Wang, Pascal Spincemaille, Moonsoo M. Jin, Marjan Zaman, Thanh D. Nguyen
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific Reports
Scientific Reports
The use of magnetic fluid hyperthermia (MFH) for cancer therapy has shown promise but lacks suitable methods for quantifying exogenous irons such as superparamagnetic iron oxide (SPIO) nanoparticles as a source of heat generation under an alternating
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbd77207b546db1ecdebc29f85a6a5fb
http://link.springer.com/article/10.1038/s41598-020-58219-9
http://link.springer.com/article/10.1038/s41598-020-58219-9