Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Marjan ZARIF-YEGANEH"'
CRISPR/Cas9 RET Gene Knockout in Medullary Thyroid Carcinoma Cell-lines: Optimization and Validation
Autor:
Marjan Zarif-Yeganeh, Dariush D Farhud, Azam Rahimpour, Sara Sheikholeslami, Setareh Shivaei, Mehdi Hedayati
Publikováno v:
Iranian Journal of Public Health, Vol 51, Iss 5 (2022)
Background: Medullary Thyroid Cancer (MTC) is a very aggressive type of thyroid carcinoma. Mutation in RET proto-oncogene is demonstrated in MTC development. We aimed to knock-out of RET-oncogene using CRISPR/Cas9 genome editing method in MTC cell-li
Externí odkaz:
https://doaj.org/article/dcd9d337497344bbb5934e04f4fa6ccb
Autor:
Dariush D. Farhud, Marjan Zarif-Yeganeh, Atefeh Mehrabi, Ali-Reza Afshari, Mohammad Bagher Rokni, Keyvan Majidi, Maryam Jalali, Ali Akbar Amir Zargar, Abdolfattah Sarafnejad, Hamid Reza Sadeghipour, Shaghayegh Zokaei, Farideh Khosravi, Mahmoud Jalali, Mohammad Khazeni
Publikováno v:
Iranian Journal of Public Health, Vol 51, Iss 4 (2022)
Background: Calcium is a necessary mineral for life to keep the body and bones healthy. Various factors including hormones, diet, age, and gender affect serum calcium status. The aim of this sturdy was to assess the serum calcium level (SCL) of Tehra
Externí odkaz:
https://doaj.org/article/d712c283b33e4f9bac5eff05852ee9e6
Autor:
Sara Sheikkholeslami, Fereidoun Azizi, Asghar Ghasemi, Abbas Alibakhshi, Hossein Parsa, Setareh Shivaee, Marjan Zarif-Yeganeh, Mehdi Hedayati, Ladan Teimoori-Toolabi
Publikováno v:
Iranian Journal of Public Health, Vol 51, Iss 3 (2022)
Background: Epigenetic alterations such as DNA methylation are known as the main cause of different types of cancers through inactivation of tumor suppressor genes, especially thyroid cancer. Identification of novel and effective markers are importan
Externí odkaz:
https://doaj.org/article/2007f0372d8e4b23adb779850d3e4b53
Autor:
Farnoush ALIAZAMI, Dariush D. FARHUD, Marjan ZARIF-YEGANEH, Siamak SALEHI, Azam HOSSEINIPOUR, Roxana SASANFAR, Maryam Eslami
Publikováno v:
Iranian Journal of Public Health, Vol 49, Iss 11, Pp 2128-2135 (2020)
Background: Hearing loss (HL) is one of the most common heterogeneous congenital disabilities worldwide. Gap junction protein β-3 (GJB3) gene encodes Connexin31 protein (Cx31). The hereditary type of hearing impairment in this gene are known to caus
Externí odkaz:
https://doaj.org/article/cef6a33e24324cc1a0c3b88e77a90d5b
Autor:
Hajar Aryan, Ehsan Razmara, Dariush Farhud, Marjan Zarif-Yeganeh, Shaghayegh Zokaei, Seyed Abbas Hassani, Mahmoud Reza Ashrafi, Masoud Garshasbi, Ali Reza Tavasoli
Publikováno v:
BMC Neurology, Vol 20, Iss 1, Pp 1-11 (2020)
Abstract Background Stress-induced childhood-onset neurodegeneration with variable ataxia and seizures (CONDSIAS) is an autosomal recessive disorder caused by defects in the ADP-Ribosylhydrolase Like 2 (ADPRHL2; OMIM: 618170) gene. This gene encodes
Externí odkaz:
https://doaj.org/article/c3bd71eda77b46f8a5127f8506b8bfb9
Publikováno v:
Iranian Journal of Public Health, Vol 50, Iss 9 (2021)
No Abstract
Externí odkaz:
https://doaj.org/article/f419814e36fc48ea8c7558bca45cf8d7
Autor:
Mahsa RAHMANI SAMANI, Marjan ZARIF-YEGANEH, Atefeh MEHRABI, Amir Nader EMAMI RAZAVI, Sara SHEIKHOLESLAMI, Mehdi HEDAYATI
Publikováno v:
Iranian Journal of Public Health, Vol 50, Iss 2 (2021)
Background: Medullary thyroid cancer (MTC) accounts for 5%–10% of all thyroid cancers, but causes 13% of all thyroid cancer related deaths. MicroRNAs (miRs) have key functions in the development and progression of MTC. Altered expression of some mi
Externí odkaz:
https://doaj.org/article/2f416ce41d294024a402ffa6230021d0
Publikováno v:
Iranian Journal of Public Health, Vol 49, Iss 12 (2020)
Over the last few years, the development of genome editing has revolutionized research on the human genome. Recent advances in developing programmable nucleases, such as meganucleases, ZFNs, TALENs and Clustered Regularly Interspaced Short Palindromi
Externí odkaz:
https://doaj.org/article/77359116102143b59bf52b331d677624
Publikováno v:
Iranian Journal of Public Health, Vol 49, Iss 3 (2020)
The Charcot-Marie-Tooth disease is a group of progressive disorders that affects the peripheral nerves and results in loss of sensation and atrophy of muscles in lower limbs. There are several types of Charcot-Marie-Tooth and multiple genes are assoc
Externí odkaz:
https://doaj.org/article/ed5bbe8b12204a4483f42fd54fe55a29
Autor:
Dariush D. FARHUD, Atefeh MEHRABI, Abdolfattah SARAFNEJAD, Hamid Reza SADEGHIPOUR, Abbas RAHIMIFOROUSHANI, Mohammdad Bagher ROKNI, Keyvan MAJIDI, Ahad ALIZADEH, Marjan ZARIF-YEGANEH, Maryam JALALI, Mahmoud JALALI, Ali Akbar AMIR ZARGAR, Farideh KHOSRAVI, Amir MOMENI, Mohammad KHAZENI, Asadallah HENDIANI, Mehdi AHMADI, Alireza DEHSHIRI, Payam RASOOLI
Publikováno v:
Iranian Journal of Public Health, Vol 48, Iss 4 (2019)
Background: Vitamin D is an essential substance for absorption of calcium and phosphorus from intestine so it is vital for muscles and skeletal development. Deficiency of this vitamin is pandemic. The vitamin D status depends on the different factors
Externí odkaz:
https://doaj.org/article/015d0ecad6884a51bc60ad69e508bc9c