Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Marjan Ruevekamp"'
Autor:
Fiona A. Stewart, Martijn Triesscheijn, Ninja Antonini, Marjan Ruevekamp, Paul Baas, Herman Neering M.D.
Publikováno v:
Photochemistry and Photobiology. 82:1686-1690
Meso-tetra-hydroxyphenyl-chlorin (mTHPC)-mediated photodynamic therapy (PDT) has shown to be effective in the treatment of patients with multiple basal cell carcinoma (BCC). In the present study we further optimized the drug-light interval and examin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e960ff3a0984634c212325020fdfca0c
https://doi.org/10.1111/j.1751-1097.2006.tb09831.x
https://doi.org/10.1111/j.1751-1097.2006.tb09831.x
Publikováno v:
Photochemistry and photobiology, 80(2), 236-241. Wiley-Blackwell
The phototoxic effect of meso-tetra-hydroxyphenyl-chlorin (mTHPC)-mediated photodynamic therapy (PDT) on human microvascular endothelial cells (hMVEC) was compared with that on human fibroblasts (BCT-27) and two human tumor cell lines (HMESO-1 and HN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12973954549303f93a418606eca73fa8
http://www.scopus.com/inward/record.url?scp=9144239901&partnerID=8YFLogxK
http://www.scopus.com/inward/record.url?scp=9144239901&partnerID=8YFLogxK
Publikováno v:
British Journal of Cancer
Clinical photodynamic therapy (PDT) schedules are based on the assumption that optimum drug-light intervals are times at which there is a maximum differential between photosensitiser retention in the tumour and surrounding normal tissue. However, vas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee2a08a764afbcc285635c83caadc160
https://doi.org/10.1038/sj.bjc.6600682
https://doi.org/10.1038/sj.bjc.6600682
Autor:
Ruth B. Veenhuizen, Adrian Timmers, Hugo Oppelaar, Fiona A. Stewart, I. Bing Tan, Marjan Ruevekamp
Publikováno v:
Head & Neck. 21:434-441
Background Photodynamic therapy (PDT) is being evaluated for treatment of localized head and neck cancer. “Light dose” is usually prescribed as incident fluence, which takes no account of reflected and scattered light. This study investigates var
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c36bd298b1d34de88bceb27aaf0f9e6a
https://doi.org/10.1002/(sici)1097-0347(199908)21:5<434::aid-hed9>3.0.co
https://doi.org/10.1002/(sici)1097-0347(199908)21:5<434::aid-hed9>3.0.co
Autor:
Ruth B. Veenhuizen, Theo J.M. Helmerhorst, Marjan Ruevekamp, Fiona A. Stewart, Peter Kenemans, Hugo Oppelaar
Publikováno v:
International Journal of Cancer. 73:230-235
Distribution of the photosensitizer Foscant (meta-tetrahydroxyphenylchlorin, mTHPC), after i.v. or i.p. injection, was investigated in Wag/Rij rats bearing i.p. tumours. These results were compared with the efficacy of mTHPC-mediated photodynamic the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::efc7b84093a9653e862f04457f348daa
https://doi.org/10.1002/(sici)1097-0215(19971009)73:2<230::aid-ijc12>3.0.co
https://doi.org/10.1002/(sici)1097-0215(19971009)73:2<230::aid-ijc12>3.0.co
Autor:
Jan H.M. Schellens, Ruth B. Veenhuizen, Fiona A. Stewart, Otilia Dalesio, Marjan Ruevekamp, Hugo Oppelaar
Publikováno v:
International Journal of Cancer. 73:236-239
Preferential retention of photosensitizers in tumours has always been one of the major goals in the search for new photosensitizers and has determined the design of clinical trials with respect to the interval between drug administration and illumina
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f136f1d534c4b2bc20a45c6e6fc2850a
https://doi.org/10.1002/(sici)1097-0215(19971009)73:2<236::aid-ijc13>3.0.co
https://doi.org/10.1002/(sici)1097-0215(19971009)73:2<236::aid-ijc13>3.0.co
Autor:
Gerrit Los, Hub P.J.M. Noteborn, Els Verdegaal, Daan ten Bokkel Huinink, J. Gordon McVie, Alexander de Graeff, Eelco W. Meesters, Marjan Ruevekamp
Publikováno v:
Biochemical Pharmacology. 42:357-363
We have studied the cellular pharmacokinetics of carboplatin (CBDCA), as part of the evaluation of the antitumor activity of CBDCA in cancers limited to the peritoneal cavity in comparison with cisplatin (cDDP). The uptake of CBDCA into L1210 (lympho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73f0d846d319dbfa317f429aeca44a10
https://doi.org/10.1016/0006-2952(91)90723-i
https://doi.org/10.1016/0006-2952(91)90723-i
Publikováno v:
Clinical otolaryngology, 32(3), 185-189. Wiley-Blackwell
Objectives: Multiple primary tumours are a common problem in the head and neck cancer patients. Curative surgery or radiotherapy of these tumours can be very mutilating or even impossible. This study aims at evaluating meta-tetrahydroxy-phenyl chlori
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1741daffe5fc59572c917510a7b22cd8
https://pubmed.ncbi.nlm.nih.gov/18429885
https://pubmed.ncbi.nlm.nih.gov/18429885
The pharmacokinetic behavior of the photosensitizer meso-tetra-hydroxyphenyl-chlorin in mice and men
Autor:
Martijn Triesscheijn, Theo J.C. Van Berkel, Marjan Ruevekamp, Ruud Out, Jan H.M. Schellens, Paul Baas, Fiona A. Stewart
Publikováno v:
Cancer chemotherapy and pharmacology. 60(1)
Meso-tetra-hydroxyphenyl-chlorin (mTHPC) is a hydrophobic photosensitizer that binds to plasma lipoproteins after intravenous injection. In vitro experiments with human plasma have shown that mTHPC initially binds to an unknown protein and subsequent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dd12e255b4a5f27e9302dce05607605
https://pubmed.ncbi.nlm.nih.gov/17009028
https://pubmed.ncbi.nlm.nih.gov/17009028
Autor:
Dirk J. Faber, Maurice C. G. Aalders, Marjan Ruevekamp, Martijn de Bruin, Martijn Triesscheijn, Fiona A. Stewart, Paul Baas
Publikováno v:
Journal of biomedical optics, 11(4). SPIE
We investigated the feasibility of using optical coherence tomography (OCT) for noninvasive real-time visualization of the vascular effects of photodynamic therapy (PDT) in normal and tumor tissue in mice. Perfusion control measurements were initiall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f09d29edf102c8595d5e05b6c09411c
https://doi.org/10.1117/1.2337302
https://doi.org/10.1117/1.2337302