Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Marjan Jeselnik"'
Autor:
Sidath C. Kumarapperuma, Colleen B. Jonsson, Jeffrey B. Arterburn, Marjan Jeselnik, William B. Parker, Yanjie Sun, Kiwon Chung
Publikováno v:
Bioorganic & Medicinal Chemistry Letters
Graphical abstract Variation of the 3-substituents in a series of bioisosteric and homologated 1-β-d-ribofuranosyl-1,2,4-triazoles has marked effects on activity with the human adenosine kinase, and analysis of computational descriptors and binding
Autor:
Colleen B. Jonsson, Frederick Tapaha, Marjan Jeselnik, Jeffrey B. Arterburn, J. Jacob Strouse, William B. Parker
Publikováno v:
Tetrahedron Letters. 46:5699-5702
The synthesis of a series of N1-aryl inosine and guanosine derivatives is described. The procedure for chemoselective N1-arylation involves the mild oxidative copper(II) mediated coupling with boronic acids. This approach provides access to substitut
Autor:
Kathryn A. Hanley, Jeffrey B. Arterburn, Sarah R. Gonzales, Michael McDowell, Marjan Jeselnik, Sidath C. Kumarapperuma
Publikováno v:
Antiviral Research. 87:78-80
Antiviral therapies are urgently needed to control emerging flaviviruses such as dengue, West Nile, and yellow fever. Ribavirin (RBV) has shown activity against flaviviruses in cultured cells, but efficacy in animal models has generally been poor. In
Publikováno v:
Carbohydrate Research. 328:591-597
A general stereoselective method for the synthesis of 4-deoxynovobiocin-related glycosides is described. 3-Benzoylamino-2 H -1-benzopyran-7-yl 2,3,4,6-tetra- O -acetyl- d -glycopyranosides of glucose, galactose and mannose were synthesised from appro
Publikováno v:
ChemInform. 33
The reaction of neat 5- or 8-oxobenzopyran-2(1H)-ones, 1–3, with a variety of aromatic and heteroaromatic hydrazines, 4, is remarkably accelerated upon irradiation in a household microwave oven in the absence of any catalyst, solid support or solve
Autor:
William B. Parker, Frederick Tapaha, J. Jacob Strouse, Marjan Jeselnik, Colleen B. Jonsson, Jeffrey B. Arterburn
Publikováno v:
ChemInform. 36
The synthesis of a series of N1-aryl inosine and guanosine derivatives is described. The procedure for chemoselective N1-arylation involves the mild oxidative copper(II) mediated coupling with boronic acids. This approach provides access to substitut
Publikováno v:
Croatica Chemica Acta
Volume 77
Issue 1-2
Volume 77
Issue 1-2
This communication describes a convenient, direct ring closure of a novel 4-cyano-5-cyanomethyl-1-(β-D-ribofuranosyl)-1,2,3-triazole under basic conditions into 4-amino-6-alkoxy-1-(β-D-ribofuranosyl)-1,2,3-triazolo[4,5-c]pyridine, which can be easi
Publikováno v:
Nucleosides, nucleotidesnucleic acids. 23(1-2)
The crystal‐structure determination of the molecular structure of the hydrophobic compound, 4‐cyano‐5‐cyanomethyl‐1‐(2,3,5‐tri‐O‐acetyl‐β‐d‐ribofuranosyl)‐1,2,3‐triazole, C16H17N5O7, provides us with two different conform
Publikováno v:
ChemInform. 34
[reaction: see text] A new synthesis of L-noviose (11), a sugar moiety of novobiocin, is presented. D-Gulonolactone was initially converted in a few steps to the key ester derivative 7 [1-O-benzyl methyl 2,3-O-(1-methylethylidene)-alpha-L-lyxofuranos
Publikováno v:
Chemical communications (Cambridge, England). (18)
The reaction of neat 5- or 8-oxobenzopyran-2(1H)-ones, 1–3, with a variety of aromatic and heteroaromatic hydrazines, 4, is remarkably accelerated upon irradiation in a household microwave oven in the absence of any catalyst, solid support or solve