Zobrazeno 1 - 10
of 92
pro vyhledávání: '"Marjan Gharagozloo"'
Autor:
Hannah Kapell, Luca Fazio, Julia Dyckow, Sophia Schwarz, Andrés Cruz-Herranz, Christina Mayer, Joaquin Campos, Elisa D’Este, Wiebke Möbius, Christian Cordano, Anne-Katrin Pröbstel, Marjan Gharagozloo, Amel Zulji, Venu Narayanan Naik, Anna Delank, Manuela Cerina, Thomas Müntefering, Celia Lerma-Martin, Jana K. Sonner, Jung Hyung Sin, Paul Disse, Nicole Rychlik, Khalida Sabeur, Manideep Chavali, Rajneesh Srivastava, Matthias Heidenreich, Kathryn C. Fitzgerald, Guiscard Seebohm, Christine Stadelmann, Bernhard Hemmer, Michael Platten, Thomas J. Jentsch, Maren Engelhardt, Thomas Budde, Klaus-Armin Nave, Peter A. Calabresi, Manuel A. Friese, Ari J. Green, Claudio Acuna, David H. Rowitch, Sven G. Meuth, Lucas Schirmer
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 7 (2023)
Multiple sclerosis (MS) is a progressive inflammatory demyelinating disease of the CNS. Increasing evidence suggests that vulnerable neurons in MS exhibit fatal metabolic exhaustion over time, a phenomenon hypothesized to be caused by chronic hyperex
Externí odkaz:
https://doaj.org/article/3d8107c041ee41648aa17c5d82d19237
Publikováno v:
Caspian Journal of Internal Medicine, Vol 13, Iss Covid 19 Supplement 2, Pp 155-160 (2022)
Women live longer than men. Cardiovascular disorders, cancers, serious infectious conditions are less common among women than men. Recent data also indicate that women, particularly before menopause, are less susceptible to severe COVID-19, a viral i
Externí odkaz:
https://doaj.org/article/1722326cd1c645798841c3f332907d8b
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
Multiple sclerosis (MS) is a chronic inflammatory, demyelinating, and neurodegenerative disease of the central nervous system (CNS). In people with MS, impaired remyelination and axonal loss lead to debilitating long-term neurologic deficits. Current
Externí odkaz:
https://doaj.org/article/3110081747904d4287de0ec81fb0d769
Autor:
Matthew D. Smith, Xitiz Chamling, Alexander J. Gill, Hector Martinez, Weifeng Li, Kathryn C. Fitzgerald, Elias S. Sotirchos, Dorota Moroziewicz, Lauren Bauer, Daniel Paull, Marjan Gharagozloo, Pavan Bhargava, Donald J. Zack, Valentina Fossati, Peter A. Calabresi
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
Astrocytes are instrumental in maintaining central nervous system (CNS) homeostasis and responding to injury. A major limitation of studying neurodegenerative diseases like multiple sclerosis (MS) is lack of human pathological specimens obtained duri
Externí odkaz:
https://doaj.org/article/5803ad7471a74cfb84d0c6510afbb242
Publikováno v:
Clinical Case Reports, Vol 10, Iss 1, Pp n/a-n/a (2022)
Abstract Abnormal iron accumulation in vital organs is one of the major complications of β‐thalassemia intermedia (β‐TI). Silymarin, a flavonolignan isolated from Silybum marianum, significantly decreases the serum ferritin levels of β‐TI pa
Externí odkaz:
https://doaj.org/article/50e794201544470aa20ea5dc3f8704ac
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
Mouse behavior is a primary outcome in evaluations of therapeutic efficacy. Exhaustive, continuous, multiparametric behavioral phenotyping is a valuable tool for understanding the pathophysiological status of mouse brain diseases. Automated home cage
Externí odkaz:
https://doaj.org/article/e608316189d840fb982b044e8331f4a1
Autor:
Katsiaryna V Gris, Kenzo Yamamoto, Marjan Gharagozloo, Shaimaa Mahmoud, Camille Simard, Pavel Gris, Denis Gris
Publikováno v:
AIMS Medical Science, Vol 5, Iss 3, Pp 238-251 (2018)
Technological advances in computer vision led to the development of various algorithms that are designed to analyze human and animal behavior. We have used an algorithm based on hidden Markov model to monitor the behavior of two different knock-out m
Externí odkaz:
https://doaj.org/article/78d76ba2be5040a082e29bfedb5615d1
Autor:
Marjan Gharagozloo, Shaimaa Mahmoud, Camille Simard, Kenzo Yamamoto, Diwakar Bobbala, Subburaj Ilangumaran, Matthew D Smith, Albert Lamontagne, Samir Jarjoura, Jean-Bernard Denault, Véronique Blais, Louis Gendron, Carles Vilariño-Güell, A Dessa Sadovnick, Jenny P Ting, Peter A Calabresi, Abdelaziz Amrani, Denis Gris
Publikováno v:
PLoS Biology, Vol 17, Iss 9, p e3000451 (2019)
Nucleotide-binding, leucine-rich repeat containing X1 (NLRX1) is a mitochondria-located innate immune sensor that inhibits major pro-inflammatory pathways such as type I interferon and nuclear factor-κB signaling. We generated a novel, spontaneous,
Externí odkaz:
https://doaj.org/article/58ac34a8bf8e4f90ae99175810c13f3c
Publikováno v:
Advanced Pharmaceutical Bulletin, Vol 5, Iss 5, Pp 653-660 (2015)
Purpose: Thymol and carvacrol, two main components of thyme, have shown anti-inflammatory effects. The aim of this study was to assess the effects of these components on Jurkat leukemia cells as an in vitro T cell model and their molecular mechanisms
Externí odkaz:
https://doaj.org/article/22107026328a45c68e2af92647927700
Autor:
Kenzo Yamamoto, Katsiaryna V. Gris, Jesús E. Sotelo Fonseca, Marjan Gharagozloo, Shaimaa Mahmoud, Camille Simard, Daphné Houle-Martel, Theodore Cloutier, Pavel Gris, Denis Gris
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 12 (2018)
Using automated supervised behavioral assessment software, we recorded and analyzed 24 h non-interrupted recordings of mice for a duration of 11 days. With the assistance of free R programming, we used correlation matrix-based hierarchical clustering
Externí odkaz:
https://doaj.org/article/85c5464d26da4e308c65261a2b95d34d