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pro vyhledávání: '"Marjan Farokhyfar"'
Autor:
Jennifer M. Colquhoun, Marjan Farokhyfar, Alexander C. Anderson, Christopher R. Bethel, Robert A. Bonomo, Anthony J. Clarke, Philip N. Rather
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 3 (2023)
ABSTRACT The ADC (AmpC) β-lactamase is universally present in the Acinetobacter baumannii chromosome, suggesting it may have a yet-to-be-identified cellular function. Using peptidoglycan composition analysis, we show that overexpressing the ADC-7 β
Externí odkaz:
https://doaj.org/article/c09b7aa4fb2e419cbd3bbd5b7112233e
Autor:
Jennifer M. Colquhoun, Marjan Farokhyfar, Anna R. Hutcheson, Alexander Anderson, Christopher R. Bethel, Robert A. Bonomo, Anthony J. Clarke, Philip N. Rather
Publikováno v:
mBio, Vol 12, Iss 6 (2021)
ABSTRACT β-Lactamase expression is the major mechanism of resistance to penicillins, cephalosporins, and carbapenems in the multidrug-resistant (MDR) bacterium Acinetobacter baumannii. In fact, stable high-level expression of at least one β-lactama
Externí odkaz:
https://doaj.org/article/480fdfe5fbe64cbcafe5beec72f3166d
Autor:
David S. Weiss, Kyle A. Tipton, Eileen M. Burd, Chui Yoke Chin, Philip N. Rather, Marjan Farokhyfar
Publikováno v:
Nature microbiology
Antibiotic-resistant infections lead to 700,000 deaths per year worldwide 1 . The roles of phenotypically diverse subpopulations of clonal bacteria in the progression of diseases are unclear. We found that the increasingly pathogenic and antibiotic-r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1f0fdcc4dd5a38b6c489e8253741926
https://doi.org/10.1038/s41564-018-0151-5
https://doi.org/10.1038/s41564-018-0151-5
Publikováno v:
Antimicrobial Agents and Chemotherapy. 62
Acinetobacter baumannii strain AB5075 forms two cell types distinguished by their opaque (VIR-O) or translucent (AV-T) colonies. VIR-O cells possess a thicker capsule and are more resistant to a variety of stressors than AV-T cells. However, the dire
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32aef8eb607601e357d09a0915391c3b
https://doi.org/10.1128/aac.01188-18
https://doi.org/10.1128/aac.01188-18
Publikováno v:
MicrobiologyOpen
Colony opacity phase variation in Acinetobacter baumannii strain AB5075 is regulated by a reversible high‐frequency switch. Transposon mutagenesis was used to generate mutations that decreased the opaque to translucent switch and a gene encoding a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9897e19d31b61cc1013de31378bc5ab
https://doi.org/10.1002/mbo3.418
https://doi.org/10.1002/mbo3.418