Výsledky vyhledávání - "Marjan Emami"

A Novel Serum Marker, Total Prostate Secretory Protein of 94 Amino Acids, Improves Prostate Cancer Detection and Helps Identify High Grade Cancers at Diagnosis

Autor: Hélène Dulude, Robert K. Nam, John Trachtenberg, Marjan Emami, Ants Toi, Jonathan R. Reeves, Steven A. Narod, Chandra J. Panchal, Luc Daigneault, Linda Sugar, Michael Jewett

Publikováno v: Journal of Urology. 175:1291-1297

Purpose: New biomarkers for prostate cancer are needed. We determined whether a novel serum marker, total PSP94 can be used to accomplish these goals.Materials and Methods: We conducted a case-control study of 1,212 men with no previous history of pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e3e669eeaaa0d4a404828e502e127970
https://doi.org/10.1016/s0022-5347(05)00695-6

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The Use of Genetic Markers to Determine Risk for Prostate Cancer at Prostate Biopsy

Autor: Linda Sugar, John Trachtenberg, Joan Sweet, Robert K. Nam, Laurence Klotz, Michael Jewett, Marjan Emami, Ants Toi, William Zhang, Steven A. Narod

Publikováno v: Clinical Cancer Research. 11:8391-8397

Purpose: We examined a panel of 13 polymorphisms in 13 different genes to determine whether specific genotypes can help predict prostate cancer at the time of biopsy among men prescreened with prostate-specific antigen and digital rectal exam. Experi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86b0f74ff98ffc8c00d56680f70c5c1f
https://doi.org/10.1158/1078-0432.ccr-05-1226

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Serum Insulin-Like Growth Factor-I Levels and Prostatic Intraepithelial Neoplasia: A Clue to the Relationship Between IGF-I Physiology and Prostate Cancer Risk

Autor: Marjan Emami, Michael A.S. Jewett, Andrew Evans, Robert K. Nam, Steven A. Narod, John Trachtenberg, Ants Toi, Michael Pollak

Publikováno v: Cancer Epidemiology, Biomarkers & Prevention. 14:1270-1273

Serum insulin-like growth factor-I (IGF-I) levels at the higher end of the reference range have been associated with increased risk for the future development of prostate cancer. We determined whether high serum IGF-I levels are associated with preca

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4dd7372dceccedc0169d44681a71b7f5
https://doi.org/10.1158/1055-9965.epi-04-0430

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Single Nucleotide Polymorphism of the Human Kallikrein-2 Gene Highly Correlates With Serum Human Kallikrein-2 Levels and in Combination Enhances Prostate Cancer Detection

Autor: Andrew Evans, Robert K. Nam, Marjan Emami, Eleftherios P. Diamandis, William Zhang, Ants Toi, Michael A.S. Jewett, Steven A. Narod, John Trachtenberg, Minnie Ho, Joan Sweet

Publikováno v: Journal of Clinical Oncology. 21:2312-2319

Purpose: We examined the relationship between a mutant (T) for wild-type (C) allele substitution of the human kallikrein-2 gene (KLK2), circulating human kallikrein-2 (hK2) levels and prostate cancer risk. Patients and Methods: We studied 1,287 conse

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cc6e142b5476911ec75d6d405c9390f
https://doi.org/10.1200/jco.2003.11.007

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A genetic sequence variant (GSV) at susceptibility loci of 5p15.33 (TERT-CLPTM1L) is associated with survival outcome in locally advanced and metastatic non-small-cell lung cancer (NSCLC)

Autor: Wei Xu, Geoffrey Liu, Ronald Feld, Abul Kalam Azad, Nicole Perera, Qin Kuang, Zhuo Chen, Xin Qiu, Sinead Cuffe, Ming-Sound Tsao, Marjan Emami, Dangxiao Cheng, Prakruthi R. Palepu, Devalben Patel, Frances A. Shepherd, Kevin Boyd, Natasha B. Leighl

Publikováno v: Lung cancer (Amsterdam, Netherlands). 84(3)

Lung cancer is a leading cause of cancer-related mortality in North America. In addition to tobacco smoking, inherited genetic factors can also influence the development of lung cancer. These genetic factors may lead to biologically distinct subsets

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7d4600adcf290fd847f6c13eeb556a9
https://pubmed.ncbi.nlm.nih.gov/24679952

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Impact and feasibility of a comprehensive geriatric assessment in the oncology setting: a pilot study

Autor: Jennifer J. Knox, Marjan Emami, Geoffrey Liu, Shabbir M.H. Alibhai, Linda E. Coate, Nicole Perera, Natasha B. Leighl, Prakruthi R. Palepu, Anne M. Horgan

Publikováno v: American journal of clinical oncology. 35(4)

A comprehensive geriatric assessment (CGA) is an objective means of assessing the global health of older patients. While evidence suggesting its promise in improving outcome prediction in the oncology setting is growing, its benefit in guiding treatm

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df00a8c030a32bc82c1cde3fbd70fb15
https://pubmed.ncbi.nlm.nih.gov/21422992

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Nomogram prediction for prostate cancer and aggressive prostate cancer at time of biopsy: utilizing all risk factors and tumor markers for prostate cancer

Autor: Robert K, Nam, Ants, Toi, Laurence H, Klotz, John, Trachtenberg, Michael A S, Jewett, Andrew, Loblaw, Greg R, Pond, Marjan, Emami, Linda, Sugar, Joan, Sweet, Steven A, Narod

Publikováno v: The Canadian journal of urology. 13

There is a large amount of confusion in interpreting prostate specific antigen (PSA) values for prostate cancer. More precise risk assessments for prostate cancer detection are needed for men faced with an abnormal PSA.We studied a sample of 2,637 me

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::8ac33e912be355d438b2c0c0a25e2070
https://pubmed.ncbi.nlm.nih.gov/16672122

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Making sense of prostate specific antigen: improving its predictive value in patients undergoing prostate biopsy

Autor: Greg Pond, John Trachtenberg, Robert K. Nam, Marjan Emami, Joan Sweet, Michael A.S. Jewett, Steven A. Narod, Ants Toi, Linda Sugar, Laurence Klotz

Publikováno v: The Journal of urology. 175(2)

The clinical usefulness of PSA for prostate cancer screening is unclear, although the test remains in common use. New methods to interpret PSA are needed.We examined a cohort of 2,637 men who underwent prostate biopsies for abnormal DRE or PSA betwee

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7c71c3fd947844eb33f9bcbb623a025
https://pubmed.ncbi.nlm.nih.gov/16406978

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Comprehensive assessment of candidate genes and serological markers for the detection of prostate cancer

Autor: Robert K, Nam, William W, Zhang, John, Trachtenberg, Michael A S, Jewett, Marjan, Emami, Danny, Vesprini, William, Chu, Minnie, Ho, Joan, Sweet, Andrew, Evans, Ants, Toi, Michael, Pollak, Steven A, Narod

Publikováno v: Cancer epidemiology, biomarkersprevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 12(12)

We examined whether selected polymorphisms in 11 candidate genes and serum levels of insulin-like growth factor I (IGF-I) help predict the presence of prostate cancer among patients prescreened with prostate-specific antigen (PSA) and digital rectal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::15248a59d78624d3f98af8915e66170f
https://pubmed.ncbi.nlm.nih.gov/14693733

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Effect of BRM promoter variants on survival outcomes of stage III-IV non-small cell lung cancer (NSCLC) patients

Autor: Marjan Emami, David Reisman, Kevin Boyd, Geoffrey Liu, Sandy D. Der, Zhuo Chen, Sinead Cuffe, Frances A. Shepherd, Abul Kalam Azad, Wei Xu, Yonathan Brhane, Dangxiao Cheng, Lu Cheng, Xin Qiu, Natasha B. Leighl, Ming-Sound Tsao

Publikováno v: Journal of Clinical Oncology. 31:11057-11057

11057 Background: BRM, a key catalytic subunit of the SWI/SNF chromatin remodeling complex, is a putative tumor susceptibility gene in NSCLC. Loss of BRM expression occurs in 15% of NSCLC, and has been linked to adverse outcome. Recently, our group h

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f97e674365a4a5aa3fb76418640181fb
https://doi.org/10.1200/jco.2013.31.15_suppl.11057

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