Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Marjan Berishaj"'
Autor:
Antonio Strillacci, Pasquale Sansone, Vinagolu K. Rajasekhar, Mesruh Turkekul, Vitaly Boyko, Fanli Meng, Brian Houck-Loomis, David Brown, Michael F. Berger, Ronald C. Hendrickson, Qing Chang, Elisa de Stanchina, Fresia Pareja, Jorge S. Reis-Filho, Ramya Segu Rajappachetty, Isabella Del Priore, Bo Liu, Yanyan Cai, Alex Penson, Chiara Mastroleo, Marjan Berishaj, Francesca Borsetti, Enzo Spisni, David Lyden, Sarat Chandarlapaty, Jacqueline Bromberg
Publikováno v:
npj Breast Cancer, Vol 8, Iss 1, Pp 1-16 (2022)
Abstract Estrogen receptor alpha (ERα) drives mammary gland development and breast cancer (BC) growth through an evolutionarily conserved linkage of DNA binding and hormone activation functions. Therapeutic targeting of the hormone binding pocket is
Externí odkaz:
https://doaj.org/article/f78ea24d939745a8868b8fcd4d4bff37
Autor:
Viraj R. Sanghvi, Prathibha Mohan, Kamini Singh, Linlin Cao, Marjan Berishaj, Andrew L. Wolfe, Jonathan H. Schatz, Nathalie Lailler, Elisa de Stanchina, Agnes Viale, Hans-Guido Wendel
Publikováno v:
Cancers, Vol 13, Iss 4, p 639 (2021)
Inhibition of the eIF4A RNA helicase with silvestrol and related compounds is emerging as a powerful anti-cancer strategy. We find that a synthetic silvestrol analogue (CR-1-31 B) has nanomolar activity across many cancer cell lines. It is especially
Externí odkaz:
https://doaj.org/article/142ea8924c2743d0a138f72768116909
Autor:
Pasquale Sansone, Claudio Ceccarelli, Marjan Berishaj, Qing Chang, Vinagolu K. Rajasekhar, Fabiana Perna, Robert L. Bowman, Michele Vidone, Laura Daly, Jennifer Nnoli, Donatella Santini, Mario Taffurelli, Natalie N. C. Shih, Michael Feldman, Jun J. Mao, Christopher Colameco, Jinbo Chen, Angela DeMichele, Nicola Fabbri, John H. Healey, Monica Cricca, Giuseppe Gasparre, David Lyden, Massimiliano Bonafé, Jacqueline Bromberg
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-10 (2016)
ER+ breast cancer patients treated with endocrine therapies often acquire resistance and develop metastasis. In this study, the authors demonstrate that endocrine therapies can promote the self-renewal of CD133hi/ERlodrug resistant cells with metasta
Externí odkaz:
https://doaj.org/article/0f73773c836b47a9b54b97e9c2ac1634
Autor:
Qing Chang, Eirini Bournazou, Pasquale Sansone, Marjan Berishaj, Sizhi Paul Gao, Laura Daly, Jared Wels, Till Theilen, Selena Granitto, Xinmin Zhang, Jesse Cotari, Mary L. Alpaugh, Elisa de Stanchina, Katia Manova, Ming Li, Massimiliano Bonafe, Claudio Ceccarelli, Mario Taffurelli, Donatella Santini, Gregoire Altan-Bonnet, Rosandra Kaplan, Larry Norton, Norihiro Nishimoto, Dennis Huszar, David Lyden, Jacqueline Bromberg
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 15, Iss 7, Pp 848-862 (2013)
We have investigated the importance of interleukin-6 (IL-6) in promoting tumor growth and metastasis. In human primary breast cancers, increased levels of IL-6 were found at the tumor leading edge and positively correlated with advanced stage, sugges
Externí odkaz:
https://doaj.org/article/b7e0970a4f474c2bbf86725441c9b2be
Autor:
Janeen Azare, Ashley Doane, Kenneth Leslie, Qing Chang, Marjan Berishaj, Jennifer Nnoli, Kevin Mark, Hikmat Al-Ahmadie, William Gerald, Maryam Hassimi, Agnes Viale, Mary Stracke, David Lyden, Jacqueline Bromberg
Publikováno v:
PLoS ONE, Vol 6, Iss 11, p e27851 (2011)
We determined that signal transducer and activator of transcription 3 (Stat3) is tyrosine phosphorylated in 37% of primary breast tumors and 63% of paired metastatic axillary lymph nodes. Examination of the distribution of tyrosine phosphorylated (pS
Externí odkaz:
https://doaj.org/article/9ba590145ac748df97b18c28a44fa8d7
Autor:
Jacqueline Bromberg, Massimiliano Bonafé, David Lyden, Monica Cricca, Enzo Spisni, John H. Healey, Nicola Fabbri, Fabiana Perna, Alberto Benito-Martin, Laura Daly, Sabrina De Carolis, Chiara Mastroleo, Robert L. Bowman, Lauren Shapiro, Claudia Savini, Antonio Strillacci, Qing Chang, Claudio Ceccarelli, Vinagolu K. Rajasekhar, Marjan Berishaj, Pasquale Sansone
The hypothesis that microvesicle-mediated miRNA transfer converts noncancer stem cells into cancer stem cells (CSC) leading to therapy resistance remains poorly investigated. Here we provide direct evidence supporting this hypothesis, by demonstratin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::200b5527559dc904b9c479fc91381839
https://doi.org/10.1158/0008-5472.c.6509582.v1
https://doi.org/10.1158/0008-5472.c.6509582.v1
Autor:
Jacqueline Bromberg, Massimiliano Bonafé, David Lyden, Monica Cricca, Enzo Spisni, John H. Healey, Nicola Fabbri, Fabiana Perna, Alberto Benito-Martin, Laura Daly, Sabrina De Carolis, Chiara Mastroleo, Robert L. Bowman, Lauren Shapiro, Claudia Savini, Antonio Strillacci, Qing Chang, Claudio Ceccarelli, Vinagolu K. Rajasekhar, Marjan Berishaj, Pasquale Sansone
Supplementary Figures and Tables
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58d8401631445921a4cdebd7ee015ef3
https://doi.org/10.1158/0008-5472.22416542
https://doi.org/10.1158/0008-5472.22416542
Autor:
Jacqueline Bromberg, William Bornmann, Janeen Azare, Ping Zhou, Raymond Comenzo, Marjan Berishaj, Tobias Dechow, Laura Pedranzini
Supplementary Figure Legends 1-2 from Pyridone 6, A Pan-Janus–Activated Kinase Inhibitor, Induces Growth Inhibition of Multiple Myeloma Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad008961ea3cbf096e8844a6707c3028
https://doi.org/10.1158/0008-5472.22366374.v1
https://doi.org/10.1158/0008-5472.22366374.v1
Autor:
Jacqueline Bromberg, William Bornmann, Janeen Azare, Ping Zhou, Raymond Comenzo, Marjan Berishaj, Tobias Dechow, Laura Pedranzini
Supplementary Figure 2 from Pyridone 6, A Pan-Janus–Activated Kinase Inhibitor, Induces Growth Inhibition of Multiple Myeloma Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1c89ca72859582223e70f67e1032de1
https://doi.org/10.1158/0008-5472.22366377.v1
https://doi.org/10.1158/0008-5472.22366377.v1
Autor:
Jacqueline Bromberg, William Bornmann, Janeen Azare, Ping Zhou, Raymond Comenzo, Marjan Berishaj, Tobias Dechow, Laura Pedranzini
Interleukin-6 (IL-6) and the subsequent Janus-activated kinase (JAK)-dependent signaling pathways play a critical role in the pathogenesis of multiple myeloma. Here, we compared the sensitivity and specificity of a novel pan-JAK inhibitor, tetracycli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7844379ae98643036c5ee981612ad426
https://doi.org/10.1158/0008-5472.c.6495114
https://doi.org/10.1158/0008-5472.c.6495114