Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Marjaana Luukkaa"'
Autor:
Katriina Peltola, Maija Hollmen, Sanna-Mari Maula, Eeva Rainio, Raija Ristamäki, Marjaana Luukkaa, Jouko Sandholm, Maria Sundvall, Klaus Elenius, Päivi J. Koskinen, Reidar Grenman, Sirpa Jalkanen
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 11, Iss 7, Pp 629-636 (2009)
Pim-1 is an oncogenic serine/threonine kinase with poorly defined function in epithelial cancers. In this study, we determined 1) associations of Pim-1 expression with clinicopathological parameters including responsiveness to irradiation in squamoce
Externí odkaz:
https://doaj.org/article/f39f0703391348d1b7ab961cee659c25
Autor:
Harri Keski-Säntti, Marjaana Luukkaa, Timo Carpén, Anna Jouppila-Mättö, Kaisa Lehtiö, Hanna Mäenpää, Kristiina Vuolukka, Tero Vahlberg, Antti Mäkitie
Purpose Hypopharyngeal carcinoma (HPC) is typically diagnosed at late stages, the patients tend to have serious co-morbidities, distant relapses are frequent, and the related mortality remains high. The treatment paradigm of HPC has remarkably change
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9ae7acc6af4e68dfe19c0d7ec905935
http://hdl.handle.net/10138/354217
http://hdl.handle.net/10138/354217
Autor:
Petteri Hervonen, Antti Jekunen, Timo Marttila, Teppo Huttunen, Vesa Kataja, Marjaana Luukkaa, Pirkko-Liisa Kellokumpu-Lehtinen, Tapio Utriainen, Katariina Klintrup, Kalevi Pulkkanen, Anna-Liisa Kautio, Markku J Leskinen
Publikováno v:
Anticancer research. 40(12)
Background/Aim: Our phase III trial showed that biweekly docetaxel (D) is better tolerated than triweekly D in metastatic castration-resistant prostate cancer (mCRPC). The safety of biweekly cabazitaxel (CBZ) post-docetaxel was studied in mCRPC. Pati
Autor:
Marjaana Luukkaa, Terhi Jokilehto, Pauliina Kronqvist, Tero Vahlberg, Reidar Grenman, Panu Jaakkola, Heikki Minn
Publikováno v:
International Journal of Radiation Biology. 85:900-908
Prolyl hydroxylase domain proteins constitute a family of oxygen sensors that regulate the expression of hypoxia-inducible factor-1 alpha (HIF-1alpha), which mediates transcription of many genes under low oxygen concentration. PHD2 (Prolyl hydroxylas
Autor:
Kristiina Heikinheimo, Risto-Pekka Happonen, Jaana Rautava, Jouni Alin, Marjaana Luukkaa, Reidar Grénman
Publikováno v:
Oral Oncology. 43:911-919
Summary A hypothesis that OSCCs originating from different types of oral epithelia may have different patient and tumor characteristics was evaluated in this retrospective analysis of 188 patients with primary OSCC treated at Turku University Central
Autor:
Pekka T. Heikkinen, Panu Jaakkola, Terhi Jokilehto, Reidar Grénman, Pauliina Kronqvist, Heikki Minn, Marjaana Luukkaa, Krista Rantanen
Publikováno v:
Clinical Cancer Research. 12:1080-1087
PURPOSE: Hypoxia in tumors is associated with poor prognosis and resistance to treatment. The outcome of hypoxia is largely regulated by the hypoxia-inducible factors (HIF-1alpha and HIF-2alpha). HIFs in turn are negatively regulated by a family of p
Autor:
Markku J Leskinen, Marjaana Luukkaa, Petteri Hervonen, Katariina Klintrup, Ilari Lehtinen, Tapio Utriainen, Kalevi Pulkkanen, Anna-Liisa Kautio, Mikko Taalikka, Antti Jekunen, Timo Marttila, Pirkko-Liisa Kellokumpu-Lehtinen, Vesa Kataja
Publikováno v:
Journal of Clinical Oncology. 34:e16523-e16523
e16523Background: In our Prosty I trial biweekly docetaxel (D) was better tolerated and yielded longer overall survival than standard triweekly D (Kellokumpu-Lehtinen et al. Lancet Oncol 2013;14:11...
Autor:
Mikko Taalikka, Pirkko-Liisa Kellokumpu-Lehtinen, Tapio Utriainen, Anna-Liisa Kautio, Marjaana Luukkaa, Petteri Hervonen, Vesa Kataja, Timo Marttila
Publikováno v:
Journal of Clinical Oncology. 33:276-276
276 Background: Docetaxel (D) administered at 2-week intervals was better tolerated than the standard 3-week D in mCRPC. In addition, the overall survival was better with the 2-weekly D dosing in our Prosty I trial (Kellokumpu-Lehtinen et al. Lancet
Autor:
Reidar Grénman, Marjaana Luukkaa, Jyrki Vuola, Mikael Kajanti, Harri Keski-Säntti, Timo Joensuu, Jyrki Törnwall, Petri Koivunen, Jussi Laranne, Matti Pukkila, Antti Mäkitie
Publikováno v:
European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery. 264(3)
Management of oral tongue squamous cell cancer (OTSCC) remains a challenge. This nationwide study reports the used treatment approach and the outcome of OTSCC in Finland. Retrospective study of OTSCC patients in 1995-1999 with a 5-year follow-up. The
Autor:
Reidar Grénman, Marjaana Luukkaa, Tero Vahlberg, Pia Vihinen, Pauliina Kronqvist, Seppo Pyrhönen, Veli-Matti Kähäri
Publikováno v:
Headneck. 28(3)
Background. Squamous cell carcinoma of the head and neck (HNSCC) is a common cancer type. The ability for curative treatment with surgery and radiotherapy (RT) is usually highly dependent on tumor stage at the time of diagnosis. Methods. The purpose