Zobrazeno 1 - 10
of 89
pro vyhledávání: '"Marjaana, Tiainen"'
Autor:
Markus Harboe Olsen, Aksel Karl Georg Jensen, Josef Dankiewicz, Markus B. Skrifvars, Matti Reinikainen, Marjaana Tiainen, Manoj Saxena, Anders Aneman, Christian Gluud, Susann Ullén, Niklas Nielsen, Janus Christian Jakobsen
Publikováno v:
Trials, Vol 23, Iss 1, Pp 1-7 (2022)
Abstract Background Randomised clinical trials with a factorial design may assess the effects of multiple interventions in the same population. Factorial trials are carried out under the assumption that the trial interventions have no interactions on
Externí odkaz:
https://doaj.org/article/efefea2a1b70488c8ad19f6d4f18eeee
Autor:
Henriikka Ollila, Riikka Pihlaja, Sanna Koskinen, Annamari Tuulio-Henriksson, Viljami Salmela, Marjaana Tiainen, Laura Hokkanen, Johanna Hästbacka
Publikováno v:
Critical Care, Vol 26, Iss 1, Pp 1-11 (2022)
Abstract Background Cognitive impairment has emerged as a common post-acute sequela of coronavirus disease 2019 (COVID-19). We hypothesised that cognitive impairment exists in patients after COVID-19 and that it is most severe in patients admitted to
Externí odkaz:
https://doaj.org/article/f984b926ea0f41c693ffbf82718d2a64
Autor:
Riikka E. Pihlaja, Lina-Lotta S. Kauhanen, Henriikka S. Ollila, Annamari S. Tuulio-Henriksson, Sanna K. Koskinen, Marjaana Tiainen, Viljami R. Salmela, Johanna Hästbacka, Laura S. Hokkanen
Publikováno v:
Brain, Behavior, & Immunity - Health, Vol 27, Iss , Pp 100587- (2023)
Background: Subjective and objective cognitive dysfunction are reported after COVID-19 but with limited data on their congruence and associations with the severity of the acute disease. The aim of this cohort study is to describe the prevalence of su
Externí odkaz:
https://doaj.org/article/678464ae66f34515b59747788d467e87
Autor:
Samu N. Kurki, Jonas Kantonen, Karri Kaivola, Laura Hokkanen, Mikko I. Mäyränpää, Henri Puttonen, FinnGen, Juha Martola, Minna Pöyhönen, Mia Kero, Jarno Tuimala, Olli Carpén, Anu Kantele, Olli Vapalahti, Marjaana Tiainen, Pentti J. Tienari, Kai Kaila, Johanna Hästbacka, Liisa Myllykangas
Publikováno v:
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-13 (2021)
Abstract Apolipoprotein E ε4 allele (APOE4) has been shown to associate with increased susceptibility to SARS-CoV-2 infection and COVID-19 mortality in some previous genetic studies, but information on the role of APOE4 on the underlying pathology a
Externí odkaz:
https://doaj.org/article/2044334279664a359db8d3a20c8d5fbc
Autor:
Kati Valkonen, Nicolas Martinez-Majander, Gerli Sibolt, Marjaana Tiainen, Silja Räty, Tatu Kokkonen, Kimmo Lappalainen, Sami Curtze
Publikováno v:
eNeurologicalSci, Vol 27, Iss , Pp 100394- (2022)
Background and purpose: Endovascular treatment for acute ischemic stroke has become a recommended treatment option for selected patients after several randomized controlled trials have shown the effectiveness of endovascular treatment. Due to the nat
Externí odkaz:
https://doaj.org/article/4caeff8c04b04d11bafb8afe7a374d5e
Autor:
Pirkka T. Pekkarinen, Markus B. Skrifvars, Ville Lievonen, Pekka Jakkula, Laura Albrecht, Pekka Loisa, Marjaana Tiainen, Ville Pettilä, Matti Reinikainen, Johanna Hästbacka
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract Fibroblast growth factor (FGF) 21 is a marker associated with mitochondrial and cellular stress. Cardiac arrest causes mitochondrial stress, and we tested if FGF 21 would reflect the severity of hypoxia-reperfusion injury after cardiac arres
Externí odkaz:
https://doaj.org/article/832b3361350a4e4986a3f24aca74bb2f
Autor:
Antti Saraste, MD, PhD, Haitham Ballo, MD, Olli Arola, MD, PhD, Ruut Laitio, MD, PhD, Juhani Airaksinen, MD, PhD, Marja Hynninen, MD, PhD, Minna Bäcklund, MD, PhD, Emmi Ylikoski, MD, PhD, Johanna Wennervirta, MD, PhD, Mikko Pietilä, MD, PhD, Risto O. Roine, MD, PhD, Veli-Pekka Harjola, MD, PhD, Jussi Niiranen, MD, PhD, Kirsi Korpi, MD, PhD, Marjut Varpula, MD, PhD, Harry Scheinin, MD, PhD, Mervyn Maze, MB ChB, Tero Vahlberg, MSc, Timo Laitio, MD, PhD, for the Xe-HYPOTHECA Study Group, Sami Virtanen, Riitta Parkkola, Jani Saunavaara, Juha Martola, Heli Silvennoinen, Marjaana Tiainen, Juha Grönlund, Outi Inkinen, Päivi Silvasti, Eija Nukarinen, Klaus T. Olkkola
Publikováno v:
Critical Care Explorations, Vol 3, Iss 8, p e0502 (2021)
OBJECTIVES:. This explorative substudy aimed at determining the effect of inhaled xenon on left ventricular function by echocardiography in comatose survivors of out-of-hospital cardiac arrest. DESIGN:. A randomized two-group single-blinded phase 2 c
Externí odkaz:
https://doaj.org/article/b8323a7599b845a3bff9321226cde503
Autor:
Pekka Jakkula, Johanna Hästbacka, Matti Reinikainen, Ville Pettilä, Pekka Loisa, Marjaana Tiainen, Erika Wilkman, Stepani Bendel, Thomas Birkelund, Anni Pulkkinen, Minna Bäcklund, Sirkku Heino, Sari Karlsson, Hiski Kopponen, Markus B. Skrifvars
Publikováno v:
Critical Care, Vol 23, Iss 1, Pp 1-8 (2019)
Abstract Background Cerebral hypoperfusion may aggravate neurological damage after cardiac arrest. Near-infrared spectroscopy (NIRS) provides information on cerebral oxygenation but its relevance during post-resuscitation care is undefined. We invest
Externí odkaz:
https://doaj.org/article/7ecb5faec7704e17bc53a94c848ddbae
Autor:
Olli P Suomalainen, Nicolas Martinez-Majander, Gerli Sibolt, Katariina Bäcklund, Juha Järveläinen, Antti Korvenoja, Marjaana Tiainen, Nina Forss, Sami Curtze
Publikováno v:
European Stroke Journal. 8:259-267
Introduction: Computed tomography perfusion (CTP) imaging has become an important tool in evaluating acute recanalization treatment candidates. Large clinical trials have successfully used RAPID automated imaging analysis software for quantifying isc
Autor:
Pekka Jakkula, Matti Reinikainen, Johanna Hästbacka, Ville Pettilä, Pekka Loisa, Sari Karlsson, Raili Laru-Sompa, Stepani Bendel, Tuomas Oksanen, Thomas Birkelund, Marjaana Tiainen, Jussi Toppila, Antti Hakkarainen, Markus B. Skrifvars, COMACARE study group
Publikováno v:
Trials, Vol 18, Iss 1, Pp 1-9 (2017)
Abstract Background Arterial carbon dioxide tension (PaCO2), oxygen tension (PaO2), and mean arterial pressure (MAP) are modifiable factors that affect cerebral blood flow (CBF), cerebral oxygen delivery, and potentially the course of brain injury af
Externí odkaz:
https://doaj.org/article/16cad2dedf3c42f983fad7f3b2fbc7da