Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Marja-Leena Majuri"'
Publikováno v:
Frontiers in Medicine, Vol 6 (2019)
Introduction: Di-isocyanates TDI (toluene di-isocyanate), MDI (diphenylmethane di-isocyanate), and HDI (hexamethylene di-isocyanate) are the most common chemicals causing occupational asthma. Di-isocyanate inhalation has been reported to induce oxida
Externí odkaz:
https://doaj.org/article/ec2fb8dc00a548109fcc28035404037d
Autor:
Harri Alenius, Jyri Järvinen, Karl-Heinz Herzig, Markus Paananen, Mauro Alini, Marianne Haapea, Jaakko Niinimäki, Jaro Karppinen, Stefan Dudli, Eero Kyllönen, Jeffrey C. Lotz, Jukka Ketola, Dino Samartzis, Marja-Leena Majuri, Sibylle Grad, Juha Risteli, Katri Koivisto
Publikováno v:
European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society. 30(4)
Lumbar Modic change (MC) can serve as a diagnostic marker as well as an independent source of chronic low back pain (CLBP). This study aimed to test for the existence of serum biomarkers in CLBP patients with MC. Age- and sex-matched CLBP patients wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1410c12b7079f79d5a77e4978de6faf
https://pubmed.ncbi.nlm.nih.gov/33423134
https://pubmed.ncbi.nlm.nih.gov/33423134
Autor:
Marianne Haapea, Jaakko Niinimäki, Eero Kyllönen, Stefan Dudli, Juha Risteli, Dino Samartzis, Jeffrey C. Lotz, Mauro Alini, Osmo Tervonen, Marja-Leena Majuri, Sibylle Grad, Katri Koivisto, Jyri Järvinen, Harri Alenius, Jaro Karppinen
Publikováno v:
Diagnostics
Volume 9
Issue 4
Volume 9
Issue 4
The aim of the current study was to compare changes in serum biomarkers, including inflammatory mediators, signaling molecules, growth factors and markers of bone turnover after a single intravenous infusion of 5 mg zoledronic acid (ZA, a long-acting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4bd58712b696d1d7bdd5649317003a2
https://pubmed.ncbi.nlm.nih.gov/31817123
https://pubmed.ncbi.nlm.nih.gov/31817123
Autor:
Marianne Haapea, Marja-Leena Majuri, Jaakko Niinimäki, Harri Alenius, Jeffrey C. Lotz, Tatu Koskelainen, Matias Torkki, Jaro Karppinen, Henrik Wolff
Publikováno v:
European Spine Journal. 25:207-216
Modic changes (MC) are associated with low back pain (LBP). Inflammation is considered as a key factor that triggers symptoms in especially type I MC, but so far of the potential inflammatory candidates only TNFα has been linked to MC. The objective
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76de645b8bba86b268686ac45cfa093e
https://doi.org/10.1007/s00586-015-3897-y
https://doi.org/10.1007/s00586-015-3897-y
Autor:
Elina Toskala, Jukka Sipilä, Maritta Kilpeläinen, Irmeli Lindström, Harri Alenius, Marja-Leena Majuri, Camilla Mitts, Hille Suojalehto, Henrik Wolff, Anne Puustinen, Tuomas Plosila
Publikováno v:
International Forum of Allergy & Rhinology. 3:612-620
Background: Rhinitis and asthma commonly coexist and are oen regarded as "unified airways disease." Evidence exists that microRNAs are important in controlling inflam- matory processes, but lile is known about their role in air- way inflammation. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::94ef4e29cea305ece633d6071c849408
https://doi.org/10.1002/alr.21179
https://doi.org/10.1002/alr.21179
Autor:
Harri Alenius, Marja-Leena Majuri, Annika Laitinen, Anneli Lauhio, Kirsi Vuorinen, Anna Meuronen, Päivi Piirilä, Vuokko L. Kinnula, Timo Sorsa, Taina Tervahartiala, Marjukka Myllärniemi
Publikováno v:
Allergy. 65:61-68
Background: Diisocyanate-induced asthma (DIA) is known to be associated with poor prognosis. We wished to clarify if matrix metalloproteinases (MMP)-7, -8 or -9 or tissue inhibitor of matrix metalloproteinases (TIMP-1) are associated with the functio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ba4a77e3f087185f67377286ea1e6aca
https://doi.org/10.1111/j.1398-9995.2009.02146.x
https://doi.org/10.1111/j.1398-9995.2009.02146.x
Autor:
Maria A. Andersson, Sampsa Matikainen, Ossian Saris, Marja-Leena Majuri, Tari Haahtela, Harri Alenius, Marina Leino, Jari Niemelä, Henrik Wolff, Kristiina Sirola, Mirja Salkinoja-Salonen, Leena von Hertzen, Mika J. Mäkelä, Jaakko Pakarinen
Publikováno v:
International Archives of Allergy and Immunology. 149:81-90
Background: Modern lifestyle and urbanization have been associated with a raised risk for atopic diseases whereas early and long-term exposure to a farm environment confers protection against atopic sensitization. Immunomodulatory potential and micro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f6bca73a6e91d3f3c04df3632520ddb
https://doi.org/10.1159/000176310
https://doi.org/10.1159/000176310
Autor:
Harri Alenius, Ritva Luukkonen, Marja-Leena Majuri, Timo Mäntylä, Anna Meuronen, Päivi Piirilä, Henrik Wolff, Annika Laitinen, Henrik Nordman
Publikováno v:
Allergy. 63:583-591
Background: The clinical outcome of diisocyanate-induced asthma has been found to be poor despite cessation of exposure. Our aim was to study the outcome of diisocyanate-induced asthma after initiation of inhaled steroid treatment at a mean period of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2844c0dabadd74dd2c3813cbdb4fdc0b
https://doi.org/10.1111/j.1398-9995.2007.01606.x
https://doi.org/10.1111/j.1398-9995.2007.01606.x
Autor:
Sari Rautio, Harri Alenius, Sari Tillander, Maili Lehto, Marja-Leena Majuri, Rita Haapakoski, Kai Savolainen, Marina Leino, Irma Welling, Kirsti Husgafvel-Pursiainen, Juha Määttä, Henrik Wolff
Publikováno v:
Toxicological Sciences. 93:96-104
Repeated airway exposure to wood dust has long been known to cause adverse respiratory effects such as asthma and chronic bronchitis and impairment of lung function. However, the mechanisms underlying the inflammatory responses of the airways after w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::478d0c3d1c521b58fb60ea8db6559053
https://doi.org/10.1093/toxsci/kfl026
https://doi.org/10.1093/toxsci/kfl026
Autor:
Henrik Wolff, Lauri A. Laitinen, Marja-Leena Majuri, Yasushi Obase, Guoying Wang, Juha Kere, Ville Pulkkinen, Johanna Vendelin, P. Holopainen, Tari Haahtela, Marko Rehn, Harri Alenius, Paula Rytilä, Tarja Laitinen
Publikováno v:
Human Molecular Genetics. 15:1667-1679
G protein-coupled receptor 154 (GPR154) is a recently discovered asthma susceptibility gene upregulated in the airways of asthma patients. We previously observed increased pulmonary mRNA expression of the murine ortholog Gpr154 in a mouse model of ov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9be8cad0552f83c4da33e0310f1d398e
https://doi.org/10.1093/hmg/ddl090
https://doi.org/10.1093/hmg/ddl090