Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Marja Saarnilehto"'
Publikováno v:
Allergy. 69:1424-1427
2,4-Dinitrochlorobenzene (DNCB) is widely used in human clinical studies and in experimental animal studies to evoke allergic contact dermatitis. 2,4-Dinitrochlorobenzene is a potent immunogen capable of inducing contact sensitization in all humans e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8c668ce6cbd068363daca8dcf009d3d
https://doi.org/10.1111/all.12488
https://doi.org/10.1111/all.12488
Autor:
Niina Jalava, Timo Korjamo, Ari Koivisto, Ken Lindstedt, Marja Saarnilehto, Hugh Chapman, Antti Pertovaara
Publikováno v:
Basicclinical pharmacologytoxicology. 114(1)
The transient receptor potential ankyrin 1 (TRPA1) ion channel on peripheral terminals of nociceptive primary afferent nerve fibres contributes to the transduction of noxious stimuli to electrical signals, while on central endings in the spinal dorsa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca0e0d15964ac973292aa377d3f0076c
https://pubmed.ncbi.nlm.nih.gov/24102997
https://pubmed.ncbi.nlm.nih.gov/24102997
Autor:
Antti Pertovaara, Ari Koivisto, Katja Kuokkanen, Hong Wei, Marja Saarnilehto, Karl E.O. Åkerman, Ken Lindstedt, Mika Hukkanen, Hanna Viisanen, Hugh Chapman
Publikováno v:
Pharmacological research. 65(1)
Peripheral diabetic neuropathy (PDN) is a devastating complication of diabetes mellitus (DM). Here we test the hypothesis that the transient receptor potential ankyrin 1 (TRPA1) ion channel on primary afferent nerve fibers is involved in the pathogen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b1210a826931a6e26220ac6f319c8cb
https://pubmed.ncbi.nlm.nih.gov/22133672
https://pubmed.ncbi.nlm.nih.gov/22133672
Autor:
Hong Wei, Ari Koivisto, Bin Hao, Hugh Chapman, Marja Saarnilehto, Antti Pertovaara, Katja Kuokkanen, Jin-Lu Huang, Yong-Xiang Wang
Publikováno v:
PainReferences. 152(3)
The transient receptor potential ankyrin 1 (TRPA1) ion channel is expressed on nociceptive primary afferent neurons. On the proximal nerve ending within the spinal dorsal horn, TRPA1 regulates transmission to spinal interneurons, and thereby pain hyp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87a326d20366bfc02c3feb8a09beaaa5
https://pubmed.ncbi.nlm.nih.gov/21211906
https://pubmed.ncbi.nlm.nih.gov/21211906
Publikováno v:
Neuropharmacology. 58(3)
Previous results indicate that intaperitoneal administration of a TRPA1 channel antagonist attenuates diabetic hypersensitivity. We studied whether the antihypersensitivity effect induced by a TRPA1 channel antagonist in diabetic animals is explained
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3738603f9c87adaefd6bb2ff95c37b9
https://pubmed.ncbi.nlm.nih.gov/20004676
https://pubmed.ncbi.nlm.nih.gov/20004676
Publikováno v:
European Journal of Pain. 13
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4d3a1f680cc5040c8d136762e902d45d
https://doi.org/10.1016/s1090-3801(09)60395-5
https://doi.org/10.1016/s1090-3801(09)60395-5
Publikováno v:
University of Helsinki
Background The TRPA1 ion channel modulates excitability of nociceptors, and it may be activated by compounds resulting from oxidative insults. Diabetes mellitus produces oxidative stress and sensory neuropathy. The authors tested the hypothesis that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a235c52ca7b149fe02739487405d0b82
https://pubmed.ncbi.nlm.nih.gov/19512877
https://pubmed.ncbi.nlm.nih.gov/19512877