Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Mariya A. Smetanina"'
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 29, Iss 8, p 297 (2024)
Making a correct genetically based diagnosis in patients with diseases associated with mitochondrial dysfunction can be challenging both genetically and clinically, as can further management of such patients on the basis of molecular-genetic data ass
Externí odkaz:
https://doaj.org/article/80388350e91348d18353890b31a6a81b
Autor:
Mariya A. Smetanina, Valeria A. Korolenya, Alexander E. Kel, Ksenia S. Sevostyanova, Konstantin A. Gavrilov, Andrey I. Shevela, Maxim L. Filipenko
Publikováno v:
Epigenomes; Volume 7; Issue 1; Pages: 8
Epigenomic changes in the venous cells exerted by oscillatory shear stress towards the endothelium may result in consolidation of gene expression alterations upon vein wall remodeling during varicose transformation. We aimed to reveal such epigenome-
Autor:
Maksim L. Filipenko, Igor A. Zolotukhin, A. I. Kirienko, Mariya A. Smetanina, Olga Ya. Porembskaya, Aleksandr V. Sazhin
Publikováno v:
Annals of the Russian academy of medical sciences. 75:36-45
Varicose veins of the lower limbs are one of the most common and wide-spread pathology all around the world. What triggers the specific changes in a vein wall still remains unclear as well as what happens in the layers of the vein wall after the dise
Autor:
Mariya A. Smetanina, Igor P. Oscorbin, Alexandra S. Shadrina, Kseniya S. Sevost'ianova, Valeria A. Korolenya, Konstantin A. Gavrilov, Andrey I. Shevela, Arina N. Shirshova, Natalya A. Oskina, Igor A. Zolotukhin, Maxim L. Filipenko
Publikováno v:
Vascular pharmacology. 145
We examined quantitative (in terms of mtDNA/nuclear DNA) and structural (in terms of common deletions in the MT-ND4 gene region) characteristics of mitochondrial DNA (mtDNA) in varicose veins (VVs) and venous wall layers by comparing mitochondrial ge
Autor:
Mariya A. Smetanina, Igor P. Oscorbin, Alexandra S. Shadrina, Kseniya S. Sevost'ianova, Valeria A. Korolenya, Konstantin A. Gavrilov, Andrey I. Shevela, Arina N. Shirshova, Natalya A. Oskina, Igor A. Zolotukhin, Maxim L. Filipenko
Publikováno v:
Vascular Pharmacology. 148:107138
Publikováno v:
Vessel Plus.
Autor:
Kirienko Ai, Maxim L. Filipenko, Igor A. Zolotukhin, Alexandra S. Shadrina, Mariya A. Smetanina, Elena N. Voronina, Yakov A. Tsepilov, E. A. Ilyukhin, E. I. Seliverstov
Publikováno v:
Clinical Genetics. 94:191-199
Heredity plays an important role in the etiology of varicose veins (VVs). However, the genetic basis underlying this condition remains poorly understood. Our aim was to replicate top association signals from genome-wide association studies (GWASs) fo
Autor:
Mariya A. Smetanina, Kseniya S. Sevost'ianova, Elena N. Voronina, E. A. Zakharova, Evgenii I. Seliverstov, Yakov A. Tsepilov, Igor A. Zolotukhin, Alexandra S. Shadrina, E. A. Ilyukhin, Kirienko Ai, Maxim L. Filipenko, Shevela Ai
Publikováno v:
Immunologic Research. 66:141-150
Inflammation was shown to be activated in varicose veins, although its role in the development of vein wall transformation remains inconclusive. We aimed to investigate the influence of 13 inflammation-related single nucleotide polymorphisms (SNPs) T
Autor:
Maxim L. Filipenko, E. A. Zakharova, Igor A. Zolotukhin, E. A. Ilyukhin, K. S. Sevost’yanova, E. I. Seliverstov, Elena N. Voronina, Alexandra S. Shadrina, Mariya A. Smetanina, Shevela Ai, Kirienko Ai
Publikováno v:
Bulletin of Experimental Biology and Medicine. 163:650-654
We studied the effects of single nucleotide polymorphisms in the promoter regions of matrix metalloproteinase genes rs1799750 (-1607dupG) MMP1, rs243865 (C-1306T) MMP2, rs3025058 (-1171dupA) MMP3, and rs11568818 (A-181G) MMP7 on the risk of varicose
Autor:
Mariya A. Smetanina, Ekaterina Y. Plotnikova, Kseniya S. Sevost'ianova, Konstantin A. Gavrilov, Maxim L. Filipenko, Shevela Ai
Publikováno v:
European Journal of Vascular and Endovascular Surgery. 60:e75-e76