Výsledky vyhledávání - "Mariwil G. Wong"

Troglitazone, the Peroxisome Proliferator-Activated Receptor-γ Agonist, Induces Antiproliferation and Redifferentiation in Human Thyroid Cancer Cell Lines

Autor: Rasa Zarnegar, Mariwil G. Wong, Quan-Yang Duh, Hajime Kanauchi, David G. Ginzinger, William C. Hyun, Orlo H. Clark, Jin-Woo Park, Margaret Lobo, Philip Cotter

Publikováno v: Thyroid. 15:222-231

Troglitazone is a potent agonist for the peroxisome proliferator-activated receptor-gamma (PPARgamma) that is a ligand-activated transcription factor regulating cell differentiation and growth. PPARgamma may play a role in thyroid carcinogenesis sinc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1687f1ef218bf96f5a4ac96fd9cffd7e
https://doi.org/10.1089/thy.2005.15.222

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Prognostic Scoring Systems in Patients with Follicular Thyroid Cancer: A Comparison of Different Staging Systems in Predicting the Patient Outcome

Autor: Quan-Yang Duh, Philip H.G. Ituarte, Patrick A. Treseler, Orlo H. Clark, Allan Siperstein, Alessandra D'Avanzo, J. Wu, Electron Kebebew, Mariwil G. Wong

Publikováno v: Thyroid. 14:453-458

The use of prognostic scoring systems is important for predicting the survival of individuals with thyroid carcinoma. Relatively few studies have addressed this issue for patients with follicular thyroid cancer. The goal of this retrospective study w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cdd987bb2ba5228bfbce03d0bba524f
https://doi.org/10.1089/105072504323150778

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Diagnostic and Prognostic Value of Fas and Telomeric-Repeat Binding Factor-1 Genes in Adrenal Tumors

Autor: Hajime Kanauchi, Mamie Yu, Mariwil G. Wong, Quan-Yang Duh, David G. Ginzinger, Orlo H. Clark, Nobuyuki Wada

Publikováno v: The Journal of Clinical Endocrinology & Metabolism. 88:3690-3693

It is often difficult to distinguish histologically between an adrenal cortical cancer and a benign adenoma, or to predict the prognosis of patients with adrenal cortical cancers. In this investigation, we examined whether apoptosis-regulating genes,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a979061a2b6a08285f9b23331a2cff0
https://doi.org/10.1210/jc.2002-020965

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Chromosomal Aberrations by Comparative Genomic Hybridization in Hürthle Cell Thyroid Carcinomas Are Associated with Tumor Recurrence

Autor: Quan-Yang Duh, Mariwil G. Wong, Orlo H. Clark, Nobuyuki Wada, Laurent Brunaud, Daishu Miura

Publikováno v: The Journal of Clinical Endocrinology & Metabolism. 87:4595-4601

Hürthle cell thyroid neoplasms are classified as variants of follicular neoplasms, but they have distinct clinicopathological features. Chromosomal aberrations by comparative genomic hybridization (CGH) are common in Hürthle cell neoplasms. However

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d08ea786868563e5b068db6039b2498
https://doi.org/10.1210/jc.2002-020339

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Genetic Screening for MEN1 Mutations in Families Presenting with Familial Primary Hyperparathyroidism

Autor: Catharina Larsson, Orlo H. Clark, Mariwil G. Wong, Andrea Villablanca, Bin Tean Teh, Philip H.G. Ituarte, Nancy D. Perrier

Publikováno v: World Journal of Surgery. 26:907-913

A large number of families with familial isolated hyperparathyroidism (FIHP) have been reported. We wanted to determine if some of these families represent early manifestations of full-blown syndromes such as multiple endocrine neoplasia type 1 (MEN-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bc3ad2fe34c9393323e2d472fb55660
https://doi.org/10.1007/s00268-002-6617-9

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Neutralizing vascular endothelial growth factor activity inhibits thyroid cancer growth in vivo

Autor: K.Jin Kim, David M. Young, Orlo H. Clark, Euy Y. Soh, Mariwil G. Wong, Monica S. Eigelberger, Quan-Yang Duh

Publikováno v: Surgery. 128:1059-1066

Background. Without angiogenesis, tumor growth is limited to a few millimeters, the limit of diffusion. Vascular endothelial growth factor (VEGF) is an endothelial-specific mitogen and a major regulator of angiogenesis. Methods. To investigate the re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5862cdf8275576d670d1567fb8196deb
https://doi.org/10.1067/msy.2000.110430

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Phenylacetate Inhibits Growth and Vascular Endothelial Growth Factor Secretion in Human Thyroid Carcinoma Cells and Modulates Their Differentiated Function1

Autor: Quan-Yang Duh, Allan Siperstein, Electron Kebebew, Orlo H. Clark, Mariwil G. Wong

Publikováno v: The Journal of Clinical Endocrinology & Metabolism. 84:2840-2847

There is increasing evidence that phenylacetate inhibits growth and modulates differentiation in a variety of tumors with effects on gene expression, and protein prenylation and glycosylation at concentrations that have been safely used in humans. We

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4580f969a8bc34e9a2f234c71a951017
https://doi.org/10.1210/jcem.84.8.5913

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Desensitization in Normal and Neoplastic Human Thyroid Cell Lines

Autor: Mariwil G. Wong, Quan-Yang Duh, Orlo H. Clark, Euy Y. Soh, Saif S. Al-Sobhi, Allan Siperstein

Publikováno v: World Journal of Surgery. 22:552-557

Because some papillary thyroid cancers continue to grow when thyroid-stimulating hormone (TSH) levels are suppressed, we questioned whether desensitization (i.e., a decreased cAMP response to repeat stimulation with TSH) occurs in normal and neoplast

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edb83b02402a793a6ce7f91a9791686d
https://doi.org/10.1007/s002689900433

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Vascular Endothelial Growth Factor Expression Is Higher in Differentiated Thyroid Cancer than in Normal or Benign Thyroid1

Autor: Mariwil G. Wong, Richard F. Grossman, Y K Garcia, Howard D. Epstein, Orlo H. Clark, Euy Young Soh, S A Sobhi, Allan Siperstein, Quan-Yang Duh, D M Young, Y D Min

Publikováno v: The Journal of Clinical Endocrinology & Metabolism. 82:3741-3747

Vascular endothelial growth factor (VEGF) is an angiogenic factor, and its expression has been rarely demonstrated in thyroid tumors. We, therefore, investigated the expression of VEGF messenger RNA (mRNA) and production of VEGF protein in cell lines

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::884594e08e2870c34fa5c756d4219db3
https://doi.org/10.1210/jcem.82.11.4340

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Antiproliferative effect of suramin on primary cultures of human pheochromocytomas and rat PC12 pheochromocytoma cells

Autor: Quan-Yang Duh, Orlo H. Clark, Mariwil G. Wong, Andreas Zielke, Allan Siperstein, Matthias Rothmund

Publikováno v: Journal of Surgical Oncology. 66:11-18

Background Suramin inhibits growth of neural crest-derived cells and is used to treat adrenocortical cancer and neuroblastoma in clinical trials. The antiproliferative effect of suramin was evaluated in primary cultures of human pheochromocytoma and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bb540269a939efeaf70034d1ce8be61d
https://doi.org/10.1002/(sici)1096-9098(199709)66:1<11::aid-jso4>3.0.co

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