Zobrazeno 1 - 10
of 186
pro vyhledávání: '"Marival Bermejo"'
Autor:
Gema J. Cabañero-Resta, Bárbara Sánchez-Dengra, Alejandro Ruiz-Picazo, Marival Bermejo, Virginia Merino, Isabel Gonzalez-Alvarez, Marta Gonzalez-Alvarez
Publikováno v:
Pharmaceutics, Vol 16, Iss 5, p 576 (2024)
Itraconazole is a drug used in veterinary medicine for the treatment of different varieties of dermatophytosis at doses between 3–5 mg/kg/day in cats. Nevertheless, in Spain, it is only available in the market as a 52 mL suspension at 10 mg/mL. The
Externí odkaz:
https://doaj.org/article/00451bfc92f04f01a61da5add29a91de
Autor:
Isabel Gonzalez-Alvarez, Alejandro Ruiz-Picazo, Ruben Selles-Talavera, Andres Figueroa-Campos, Virginia Merino, Marival Bermejo, Marta Gonzalez-Alvarez
Publikováno v:
Pharmaceutics, Vol 16, Iss 3, p 390 (2024)
The purpose of this study was to predict the in vivo bioequivalence (BE) outcome of valsartan (VALS, BCS class IV) from three oral-fixed combination products with hydrochlorothiazide (HCTZ, BCS class III) (Co-Diovan® Forte as reference and two gener
Externí odkaz:
https://doaj.org/article/da117dad3d8f4fb28eb64ecc2b9cbb53
Autor:
Ivan Qart-Fernández, Marival Bermejo, Marta González-Álvarez, Ana Melero-Zaera, Fernando Mud-Castelló, Vicente Javier Baixauli-Fernández
Publikováno v:
Farmacéuticos Comunitarios, Vol 14, Iss 3, Pp 5-14 (2022)
Introducción: según estudios recientes, los Servicios Profesionales Farmacéuticos Asistenciales (SPFA) demostraron sus beneficios en la calidad de vida de pacientes y sistemas de salud. Los SPFA son actividades sanitarias prestadas desde la farmac
Externí odkaz:
https://doaj.org/article/49c18641f8354acea997b580a646ecc0
Autor:
Bárbara Sánchez-Dengra, Elena García-Montoya, Isabel González-Álvarez, Marival Bermejo, Marta González-Álvarez
Publikováno v:
Pharmaceutics, Vol 15, Iss 5, p 1431 (2023)
Currently, the mechanisms involved in drug access to the central nervous system (CNS) are not completely elucidated, and research efforts to understand the behaviour of the therapeutic agents to access the blood–brain barrier continue with the utmo
Externí odkaz:
https://doaj.org/article/5b607623f67f45ab958ebb3b8225876b
Autor:
Isabel González-Álvarez, Bárbara Sánchez-Dengra, Raquel Rodriguez-Galvez, Alejandro Ruiz-Picazo, Marta González-Álvarez, Alfredo García-Arieta, Marival Bermejo
Publikováno v:
Pharmaceutics, Vol 14, Iss 12, p 2565 (2022)
Some years ago, excipients were considered inert substances irrelevant in the absorption process. However, years of study have demonstrated that this belief is not always true. In this study, the reasons for a bioequivalence failure between two formu
Externí odkaz:
https://doaj.org/article/c59935dd1d544a3f870878e72c51ca57
Autor:
Valeria Gigante, Giovanni M. Pauletti, Sabine Kopp, Minghze Xu, Isabel Gonzalez-Alvarez, Virginia Merino, Michelle P. McIntosh, Anita Wessels, Beom-Jin Lee, Kênnia Rocha Rezende, Gerhard K.E. Scriba, Gaurav P. S. Jadaun, Marival Bermejo
Publikováno v:
ADMET and DMPK (2020)
The WHO Biopharmaceutical Classification System (BCS) is a practical tool to identify active pharmaceutical ingredients (APIs) that scientifically qualify for a waiver of in vivo bioequivalence studies. The focus of this study was to engage a global
Externí odkaz:
https://doaj.org/article/5208c09f597b4583abb12e3bc52f96ba
Autor:
Evren Gundogdu, Emine-Selin Demir, Meliha Ekinci, Emre Ozgenc, Derya Ilem-Ozdemir, Zeynep Senyigit, Isabel Gonzalez-Alvarez, Marival Bermejo
Publikováno v:
Nanomaterials, Vol 12, Iss 2, p 250 (2022)
Imatinib (IMT) is a tyrosine kinase enzyme inhibitor and extensively used for the treatment of gastrointestinal stromal tumors (GISTs). A nanostructured lipid carrier system (NLCS) containing IMT was developed by using emulsification–sonication met
Externí odkaz:
https://doaj.org/article/eb81636e80164718be67c99506151091
Autor:
Claudia Miranda, Alejandro Ruiz-Picazo, Paula Pomares, Isabel Gonzalez-Alvarez, Marival Bermejo, Marta Gonzalez-Alvarez, Alex Avdeef, Miguel-Ángel Cabrera-Pérez
Publikováno v:
Pharmaceutics, Vol 14, Iss 1, p 182 (2022)
The main aim of this work is the biopharmaceutical characterization of a new hybrid benzodiazepine-dihydropyridine derivative, JM-20, derived with potent anti-ischemic and neuroprotective effects. In this study, the pKa and the pH-solubility profile
Externí odkaz:
https://doaj.org/article/3a7494604785461ea4a616a3c294d50f
Publikováno v:
Animals, Vol 11, Iss 12, p 3521 (2021)
The development of new drugs or formulations for central nervous system (CNS) diseases is a complex pharmacologic and pharmacokinetic process; it is important to evaluate their access to the CNS through the blood–brain barrier (BBB) and their distr
Externí odkaz:
https://doaj.org/article/a67175dc2a0c414c8dd710a01e9d3fb1
Publikováno v:
Pharmaceutics, Vol 13, Iss 9, p 1402 (2021)
One of the main obstacles in neurological disease treatment is the presence of the blood–brain barrier. New predictive high-throughput screening tools are essential to avoid costly failures in the advanced phases of development and to contribute to
Externí odkaz:
https://doaj.org/article/3c0c7f0def024234b2c8249ef6b0e0cd