Proteinous Components of Neutrophil Extracellular Traps Are Arrested by the Cell Wall Proteins of Candida albicans during Fungal Infection, and Can Be Used in the Host Invasion

Autor: Angela H. Nobbs, Magdalena Smolarz, Mariusz Gogol, Justyna Karkowska-Kuleta, Marcin Zawrotniak, Andrzej Kozik, Karolina Seweryn-Ozog, Oliwia Bochenska, Maria Rapala-Kozik, Ewelina Wronowska, Dorota Satala

Publikováno v: Cells, Vol 10, Iss 2736, p 2736 (2021)
Cells
Volume 10
Issue 10
Karkowska-Kuleta, J, Smolarz, M, Seweryn-Ozog, K, Satala, D, Zawrotniak, M, Wronowska, E, Bochenska, O, Kozik, A, Nobbs, A H, Gogol, M & Rapala-Kozik, M 2021, ' Proteinous Components of Neutrophil Extracellular Traps Are Arrested by the Cell Wall Proteins of Candida albicans during Fungal Infection, and Can Be Used in the Host Invasion ', Cells, vol. 10, no. 10, 2736 . https://doi.org/10.3390/cells10102736

One of defense mechanisms of the human immune system to counteract infection by the opportunistic fungal pathogen Candida albicans is the recruitment of neutrophils to the site of invasion, and the subsequent production of neutrophil extracellular tr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4389ca6b62363d681ce16879c38700f
https://www.mdpi.com/2073-4409/10/10/2736

Extracellular proteinases of Candida species pathogenic yeasts

Autor: Mariusz Gogol, Justyna Karkowska-Kuleta, Oliwia Bochenska, Maria Rapala-Kozik, Marcin Zawrotniak, Dorota Zajac, Andrzej Kozik

The increased incidence of severe disseminated infections caused by the opportunistic yeast-like fungi Candida spp. highlights the urgent need for research into the major virulence factors of these pathogens-extracellular aspartic proteinases of the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f774381b62a271d4151ec4cf411207e
https://ruj.uj.edu.pl/xmlui/handle/item/53526

Citrullination – small change with a great consequence

Autor: Mariusz Gogol

Publikováno v: Folia Biologica et Oecologica. 9:17-25

Citrullination is one of the possible post-translational modifications of proteins. It is based on a conversion of L-arginine residue (L-Arg) to L-citrulline residue (L-Cit). The reaction is catalyzed by peptidylarginine deiminases (PAD). The change

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4e91aa82b571eb6a51e93c7da304b387
https://doi.org/10.2478/fobio-2013-0003

Inactivation of α1-proteinase inhibitor by Candida albicans aspartic proteases favors the epithelial and endothelial cell colonization in the presence of neutrophil extracellular traps

Autor: Maria Rapala-Kozik, Wataru Aoki, Natalia Wolak, Oliwia Bochenska, Mitsuyoshi Ueda, Mariusz Gogol, Dominika Ostrowska, Kinga Klaga, Andrzej Kozik

Publikováno v: Acta Biochimica Polonica. 63

Candida albicans, a causative agent of opportunistic fungal infections in immunocompromised patients, uses ten secreted aspartic proteases (SAPs) to deregulate the homeostasis of the host organism on many levels. One of these deregulation mechanisms

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ebbf9b1ff8b77bfc9676cf83f7bbc74
https://doi.org/10.18388/abp.2015_1163

Kinin release from human kininogen by 10 aspartic proteases produced by pathogenic yeast Candida albicans

Autor: Oliwia Bochenska, Maria Rapala-Kozik, Wataru Aoki, Natalia Wolak, Alexander Faussner, Mariusz Gogol, Justyna Karkowska-Kuleta, Wojciech Kamysz, Andrzej Kozik, Mitsuyoshi Ueda

Publikováno v: BMC Microbiology

Background: Candida albicans yeast produces 10 distinct secreted aspartic proteases (Saps), which are some of the most important virulence factors of this pathogenic fungus. One of the suggested roles of Saps is their deregulating effect on various p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcbee9a369f5829d31bca707f8a0b7b6
http://ruj.uj.edu.pl/xmlui/handle/item/7666